Generic Vardenafil Tablets (Vilitra 20 mg Tablets) - Product Information
Vardenafil is a Phosphodiesterase type-5 inhibitor, available in the form of tablets for oral administration. Vardenafil Hydrochloride is amedication that treats erectile dysfunction in men, who are unable to experience or maintain a proper erection during sexual activity.
The major cause of erectile dysfunction in men is due to the constriction of blood vessels in the penis which results in lower blood flow. Vardenafil tablets helps in maintaining an erection by increasing blood flow to your penis, which helps you maintain an erection.
After taking Vilitra tablets, its effect starts in about 16 minutes and lasts for a period of 4 hours. This feature of immediate and lasting effect gives Vardenafil tablets a competitive edge over other erectile dysfunction drugs such as Sildenafil Citrate (Sildenafil). Vardenafil HCl tablets are available in two different strengths, 10 mg and 20 mg.
In our online pharmacy, Vardenafil 10 mg and 20 mg tablets are available under the brand name of Vilitra tablets, manufactured by Centurion Remedies Limited, India.
We also have in stock Kamagra Oral Jelly (Sildenafil Jelly) which is also used to treat the same indications.
Name of the Drug
Vilitra tablets. Generic Vardenafil tablets are also available under other brand names such as Valif tablets, Filitra and Vivanza.
Manufacturer of Vilitra Tablets
Centurion Remedies Limited, India.
Website: www.centurionremedies.com
Active Pharmaceutical Ingredient
The active ingredient present in Vilitra tablet is Vardenafil Hydrochloride . Each Vilitra tablet contains Vardenafil Hydrochloride equivalent to 10 mg or 20 mg of Vardenafil.
What is Vardenafil? What are Vilitra Tablets Used For?
Vardenafil tablets belong to a class of medication known as Phosphodiesterase inhibitors. Vilitra tablets are used for the oral treatment of erectile dysfunction in men. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works.
Vilitra tablets are not suitable for women or for individuals under the age of 18. Vardenafil Hydrochloride tablets do not offer protection against pregnancy or the transmission of sexually transmitted diseases such as HIV virus.
Vardenafil Dosage
You should take Vardenafil tablets exactly as prescribed by your doctor. Your doctor may suggest a dosage depending on your requirement, body weight, other medical conditions, and current medications.
Vardenafil tablets should be taken on a need-basis. You can take Vardenafil tablets 25 - 60 minutes prior to sexual activity. You can choose to take Vardenafil HCl tablets with or without food. Note that the effect of Vardenafil tablets will take longer to occur if you have eaten a large or high-fat meal before the medication.
Some type of sexual stimulation is required for the occurrence of an erection after taking Vardenafil Hydrochloride tablets. Vardenafil HCl tablets should be consumed only once in a day. Do not take more than one dose of Vardenafil Hydrochloride tablets within a period of 24 hours.
Vilitra is taken as needed: For most patients, the starting dose is 10 mg, up to once daily. Increase to 20 mg or decrease to 5 mg based on efficacy/tolerability. A starting dose of 5 mg Vilitra should be considered in patients 65 years of age or more.
Please consult your doctor for exact dosing instructions. Vilitra tablets (Generic Vardenafil tablets) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.
Missed Dose
Vardenafil tablets are taken on a need basis.
A case of missed dose does not occur in such a scenario.
Vilitra Mechanism of Action – How Does Vardenafil Hydrochloride Work?
Vardenafil belongs to class of drugs called phosphodiesterase type 5 inhibitor. Vardenafil Hydrochloride tablets prevents the activity of an enzyme called phosphodiesterase type 5.
An erection during sexual stimulation develops from a cascade of events. This process requires the signals from the nervous system which would result in the release of chemical messengers in the penis. One such chemical messenger involved in this process is called cyclic GMP. Cyclic GMP relaxes the blood vessels, resulting in an increase in the size of the blood vessels in the penis. This increase in blood vessel size permits more blood to flow into the penis, which ultimately results in the penis becoming firm and erect.
Usually, cyclic GMP is suppressed by another enzyme in the body called phosphodiesterase type 5. Vardenafil Hydrochloride tablet prevents the activity of phosphodiesterase type 5, thus inhibiting the suppression of cyclic GMP. If the cyclic GMPs are available to increase the size of blood vessels, the blood vessels are kept widened for a longer period of time, continuing the enhanced blood flow to the penis and maintaining a longer erection.
As Vardenafil tablets indirectly boosts the activity of cyclic GMPS which are responsible for generating an erection, Vardenafil Hydrochloride tablets will only have an effect once these messengers are in circulation i.e. sexual stimulation is required for cyclic GMPs to produce and sustain an erection. Vardenafil dose should be taken roughly 25 minutes to one hour before the sexual activity. The effect of Vardenafil HCl 20 mg tablets can last for around four to five hours.
Storage Instructions for Vardenafil Tablets (Vilitra 10 mg and 20 mg)
Store Vilitra 10 mg and 20 mg tablets at controlled room temperature (20°C to 25°C),protected from heat, moisture, and sunlight. Excursions are permitted from 15°C to 30°C.
Retain the original packing of the medication and do not consume Vardenafil Hydrochloride tablets past its expiration date printed on the blister pack. Keep the pack of Vardenafil tablets away from the reach of children and pets.
Do not dispose Vardenafil Hydrochloride tablets along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.
Contraindications
Vilitra tablets are contraindicated in patients with a hypersensitivity to Vardenafil Hydrochloride or any inactive ingredient present in Vilitra tablets. Administration of Vilitra tablets with nitrates (either regularly and/or intermittently) and nitric oxide donors is contraindicated.Consistent with the effects of PDE5 inhibition on the nitric oxide/cyclic guanosine monophosphate pathway, PDE5 inhibitors, including Vardenafil, may potentiate the hypotensive effects of nitrates.
Overdose
The maximum dose of Vardenafil for which human data are available is a single 120 mg dose administered to healthy male volunteers. The majority of these subjects experienced reversible back pain/myalgia and/or “abnormal vision.” Single doses up to 80 mg Vardenafil and multiple doses up to 40 mg Vardenafil administered once daily over 4 weeks were tolerated without producing serious adverse side effects.
When 40 mg of Vardenafil was administered twice daily, cases of severe back pain were observed. No muscle or neurological toxicity was identified.
In cases of overdose, standard supportive measures should be taken as required. Renal dialysis is not expected to accelerate clearance as vardenafil is highly bound to plasma proteins and not significantly eliminated in the urine.
Warnings and Precautions to be taken when using Vilitra Tablets
Medical History
Before starting a course of Vilitra tablets (Generic Vardenafil), discuss your personal and family medical history with your doctor. Inform your doctor if you have had a heart attack, stroke, or life-threatening irregular heartbeat within the past 6 months; certain eye problems (retina diseases such as retinitis pigmentosa), uncontrolled chest pain, seizures, uncontrolled high blood pressure, low blood pressure, angina, irregular heartbeat (congenital QT prolongation), heart or blood vessel disease, bleeding disorder (hemophilia), severe heart failure, stomach ulcer, penis disease/injury/deformity (angulation, cavernosal fibrosis, or Peyronie's disease), sickle cell anemia, diabetes, high cholesterol, myeloma or leukemia, severe liver problems, or end-stage kidney disease that requires dialysis. Vardenafil Hydrochloride tablets are contraindicated in patients with the above disease states.
Allergy
Please inform your doctor if you have an allergy or have had an allergic reaction in the past to Vardenafil or any other inactive ingredients in Vilitra tablets (Generic Vardenafil).
Cardiovascular Effects:
Patients should not use Vardenafil if sex is inadvisable due to cardiovascular status.
Risk of Priapism:
In the event that an erection lasts more than 4 hours, the patient should seek immediate medical assistance.
Effects on the Eye:
Patients should stop use of Vardenafil , and seek medical attention in the event of sudden loss of vision in one or both eyes, which could be a sign of nonarteritic anterior ischemic optic neuropathy (NAION). Vardenafil should be used with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION. Patients with a "crowded" optic disc may also be at an increased risk of NAION.
Sudden Hearing Loss:
Patients should stop Vardenafil and seek medical attention in the event of sudden decrease or loss in hearing.
Alpha-Blockers:
Caution is advised when PDE5 inhibitors are co administered with alpha-blockers. In some patients, concomitant use of these two drug classes can lower blood pressure significantly leading to symptomatic hypotension (for example, fainting).
QT Prolongation:
Patients with congenital QT syndrome or taking class IA or III antiarrhythmics should avoid using Vardenafil.
Vardenafil and Alcohol:
Consumption of excess alcohol can reduce your ability to experience an erection. You may be deprived of the maximum benefit of Vardenafil HCl tablets (Vilitra tablets). Alcohol consumption can also increase the risk of certain side effects.
Surgery and Regular Medical Tests:
If you plan to have surgery or any dental procedure, inform your doctor or dentists about your course of Vardenafil tablets. In case of an emergency medical treatment, please inform the practitioner about your course of Vardenafil Hydrochloride tablets and the details of your last dose.
Side Effects of Vardenafil Tablets
The most common Vardenafil Tablets (Vilitra 10 mg and 20 mg) side effects reported with an incidence rate of 2% of patients or greater are headache, flushing, nasal congestion, dyspepsia, sinusitis, flu syndrome, dizziness, increased creatine kinase, nausea, back pain.
The following section identifies additional, less frequent adverse reactions (less than 2%) reported during the clinical development of Vardenafil Hydrochloride film-coated tablets and Vardenafil orally disintegrating tablets.
- Body as a whole: allergic edema and angioedema, feeling unwell, allergic reactions, chest pain
- Auditory: tinnitus, vertigo
- Cardiovascular: palpitation, tachycardia, angina pectoris, myocardial infarction, ventricular tachyarrhythmias, hypotension
- Digestive: nausea, gastrointestinal and abdominal pain, dry mouth, diarrhea, gastroesophageal reflux disease, gastritis, vomiting, increase in transaminases
- Musculoskeletal: increase in creatine phosphokinase (CPK), increased muscle tone and cramping, myalgia
- Nervous: paresthesia and dysesthesia, somnolence, sleep disorder, syncope, amnesia, seizure
- Respiratory: dyspnea, sinus congestion
- Skin and appendages: erythema, rash
- Ophthalmologic: visual disturbance, ocular hyperemia, visual color distortions, eye pain and eye discomfort, photophobia, increase in intraocular pressure, conjunctivitis
- Urogenital: increase in erection, priapism
Vardenafil Hydrochloride tablets During Pregnancy
Vardenafil Hydrochloride (Vilitra 10 mg and 20 mg tablets) is classified by the US FDA as Pregnancy Category B.
Vardenafil tablets should be used only in men. Vardenafil Tablets (Vilitra 10 mg and 20 mg Tablets) is not indicated for use in women. Women should not consume Vilitra tablets. There are no studies of Vardenafil use in pregnant women.
No evidence of specific potential for teratogenicity, embryotoxicity or fetotoxicity was observed in rats and rabbits that received Vardenafil at up to 18 mg/kg/day during organogenesis. This dose is approximately 100 fold (rat) and 29 fold (rabbit) greater than the AUC values for unbound vardenafil and its major metabolite in humans given the maximum recommended human dose (MRHD) of 20 mg.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.
Nursing Considerations
Vardenafil (Vilitra 10 mg and 20 mg tablets) is not indicated for use in women. It is not known if Vardenafil is excreted in human breast milk.
Vardenafil was secreted into the milk of lactating rats at concentrations approximately 10-fold greater than found in the plasma. Following a single oral dose of 3 mg/kg, 3.3% of the administered dose was excreted into the milk within 24 hours.
Do not use this medication without telling your doctor if you are breast-feeding a baby.
Buy Vilitra 10 mg and 20 mg (Generic Vardenafil Hydrochloride Pills) Online From Only $0.86 per Pill
You can buy Vardenafil Hydrochloride Tablets online from Everest Online Pharmacy at a cheap price. Vilitra 20 mg and 10 mg pills, manufactured by Centurion Remedies Limited, India are supplied in a blister strip of 10 tablets. The 10 mg tablets cost only $0.79 per unit when you place an order for 300 tablets.
Disclaimer
The above information is provided to the best of our knowledge and in good faith. It is without a warrant of any kind, expressed or implied.
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