Vardenafil Hydrochloride Tablets

Generic Vardenafil Tablets (Valif 20 mg Tablets) - Product Information

Vardenafil is a Phosphodiesterase type-5 inhibitor, available in the form of tablets for oral administration. Vardenafil Hydrochloride tablets are intended as an oral remedy for erectile dysfunction in men, who are unable to experience or maintain a proper erection during sexual activity.
The major cause of erectile dysfunction in men is due to the constriction of blood vessels in the penis which results in lower blood flow. Vardenafil tablets helps in maintaining an erection by relaxing the blood vessel which lead to improved blood flow.
After taking Valif tablets, its effect kicks in about 16 minutes and lasts for a period of 4 hours. This feature of immediate and lasting effect gives Vardenafil tablets a competitive edge over other erectile dysfunction drugs such as Sildenafil Citrate (Sildenafil). Vardenafil HCl tablets are available in two different strengths, 10 mg and 20 mg.
In our online pharmacy, Vardenafil 10 mg tablets are available under the brand name of Vilitra tablets, while Vardenafil 20 mg tablets are available under two brand names, Valif 20 mg tablets and Vilitra 20 mg tablets.
We also have in stock Vardenafil Jelly (Valif Oral Jelly) which is also used to treat the same indications.

Name of the Drug

Valif tablets. Generic Vardenafil tablets are also available under other brand names such as Vilitra, Filitra and Vivanza.

Manufacturer of Valif Tablets

In our online pharmacy, Vardenafil 20 mg tablets are available under two different brands. Valif tablets, which are manufactured by Ajanta Pharma Limited, India
  Website: www.ajantapharma.com .
Vardenafil 20 mg tablets are also available as Vilitra tablets, which are manufactured by Centurion Remedies

Active Pharmaceutical Ingredient

The active ingredient present in Valif tablet is Vardenafil Hydrochloride . Each Valif tablet contains Vardenafil Hydrochloride equivalent to 20 mg of Vardenafil. The inactive ingredients in Vardenafil tablets are anhydrous colloidal silica, crospovidone, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, red ferric oxide, titanium dioxide, and yellow ferric oxide.

What is Vardenafil? What are Valif Tablets Used For?

Vardenafil tablets belong to a class of medication known as Phosphodiesterase inhibitors. Valif tablets are used for the oral treatment of erectile dysfunction in men. Valif tablets are not suitable for women or for individuals under the age of 18. Vardenafil Hydrochloride tablets do not offer protection against pregnancy or the transmission of sexually transmitted diseases such as HIV virus.

Vardenafil Dosage

You should take Vardenafil tablets exactly as prescribed by your doctor. Your doctor may suggest a dosage depending on your requirement, body weight, other medical conditions, and current medications.
Vardenafil 20 mg tablets should be taken on a need-basis. You can take Vardenafil tablets 25 - 60 minutes prior to sexual activity. You can choose to take Vardenafil HCl tablets with or without food. Note that the effect of Vardenafil tablets will take longer to occur if you have eaten a large or high-fat meal before the medication.
Some type of sexual stimulation is required for the occurrence of an erection after taking Vardenafil Hydrochloride tablets. Vardenafil HCl tablets should be consumed only once in a day.
Do not take more than one dose of Vardenafil Hydrochloride tablets within a period of 24 hours.
Please consult your doctor for exact dosing instructions. Valif tablets (Generic Vardenafil tablets) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Missed Dose

Vardenafil tablets are taken on a need basis.
A case of missed dose does not occur in such a scenario.

Valif Mechanism of Action – How Does Vardenafil Hydrochloride Work?

Vardenafil belongs to class of drugs called phosphodiesterase type 5 inhibitor. Vardenafil Hydrochloride tablets prevents the activity of an enzyme called phosphodiesterase type 5.
An erection during sexual stimulation develops from a cascade of events. This process requires the signals from the nervous system which would result in the release of chemical messengers in the penis. One such chemical messenger involved in this process is called cyclic GMP. Cyclic GMP relaxes the blood vessels, resulting in an increase in the size of the blood vessels in the penis. This increase in blood vessel size permits more blood to flow into the penis, which ultimately results in the penis becoming firm and erect.
Usually, cyclic GMP is suppressed by another enzyme in the body called phosphodiesterase type 5. Vardenafil Hydrochloride tablet prevents the activity of phosphodiesterase type 5, thus inhibiting the suppression of cyclic GMP. If the cyclic GMPs are available to increase the size of blood vessels, the blood vessels are kept widened for a longer period of time, continuing the enhanced blood flow to the penis and maintaining a longer erection.
As Vardenafil tablets indirectly boosts the activity of cyclic GMPS which are responsible for generating an erection, Vardenafil Hydrochloride tablets will only have an effect once these messengers are in circulation i.e. sexual stimulation is required for cyclic GMPs to produce and sustain an erection. Vardenafil dose should be taken roughly 25 minutes to one hour before the sexual activity. The effect of Vardenafil HCl 20 mg tablets can last for around four to five hours.

Storage Instructions for Generic Vardenafil Tablets (Valif 20 mg)

Store Generic Vardenafil Hydrochloride tablets (Valif 20 mg) at controlled room temperature (20°C to 25°C),protected from heat, moisture, and sunlight. Excursions are permitted from 15°C to 30°C.
Retain the original packing of the medication and do not consume Vardenafil Hydrochloride tablets past its expiration date printed on the blister pack. Keep the pack of Vardenafil tablets away from the reach of children and pets.
Do not dispose Vardenafil Hydrochloride tablets along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.

Contraindications

Valif tablets are contraindicated in patients with a hypersensitivity to Vardenafil or any inactive ingredient present in Valif tablets. Administration of Vardenafil (Valif tablets) with nitrates (either regularly and/or intermittently) and nitric oxide donors is contraindicated.Consistent with the effects of PDE5 inhibition on the nitric oxide/cyclic guanosine monophosphate pathway, PDE5 inhibitors, including Vardenafil, may potentiate the hypotensive effects of nitrates.

Overdose

The maximum dose of Vardenafil (Valif tablets) for which human data are available is a single 120 mg dose administered to healthy male volunteers. The majority of these subjects experienced reversible back pain/myalgia and/or “abnormal vision.” Single doses up to 80 mg Vardenafil and multiple doses up to 40 mg Vardenafil administered once daily over 4 weeks were tolerated without producing serious adverse side effects. When 40 mg of Vardenafil was administered twice daily, cases of severe back pain were observed. No muscle or neurological toxicity was identified.
In cases of overdose, standard supportive measures should be taken as required. Renal dialysis is not expected to accelerate clearance as Vardenafil is highly bound to plasma proteins and not significantly eliminated in the urine.

Warnings and Precautions to be taken when using Valif Tablets

Medical History
Before starting a course of Valif tablets (Generic Vardenafil), discuss your personal and family medical history with your doctor. Inform your doctor if you have had a heart attack, stroke, or life-threatening irregular heartbeat within the past 6 months; certain eye problems (retina diseases such as retinitis pigmentosa), uncontrolled chest pain, seizures, uncontrolled high blood pressure, low blood pressure, angina, irregular heartbeat (congenital QT prolongation), heart or blood vessel disease, bleeding disorder (hemophilia), severe heart failure, stomach ulcer, penis disease/injury/deformity (angulation, cavernosal fibrosis, or Peyronie's disease), sickle cell anemia, diabetes, high cholesterol, myeloma or leukemia, severe liver problems, or end-stage kidney disease that requires dialysis. Vardenafil Hydrochloride tablets are contraindicated in patients with the above disease states.
Allergy
Please inform your doctor if you have an allergy or have had an allergic reaction in the past to Vardenafil or any other inactive ingredients in Valif tablets (Generic Vardenafil).
Vardenafil Interactions
Before staring the course of Vardenafil Hydrochloride tablets, please inform your doctor of all your current medications including prescription drugs, over the counter medications, mineral supplements, herbal products, and vitamins. Vardenafil tablets are known to have drug interactions with certain other medications. Let your doctor know if are using nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, and others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket), recreational drugs such as amyl nitrate or nitrite ("poppers"); alpha blockers such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), tamsulosin (Flomax), and terazosin (Hytrin); amiodarone (Cordarone, Pacerone); antifungals such as fluconazole (Diflucan), itraconazole (Sporanox), and ketoconazole (Nizoral); clarithromycin (Biaxin); disopyramide (Norpace); erythromycin (E.E.S., E-Mycin, Erythrocin) haloperidol (Haldol); HIV protease inhibitors including atazanavir (Reyataz), indinavir (Crixivan),ritonavir (Norvir, in Kaletra), and saquinavir (Fortovase, Invirase); medications for high blood pressure or irregular heartbeat; other medications or treatments for erectile dysfunction such as avanafil (Stendra), sildenafil (Viagra), or tadalafil (Cialis); methadone (Dolophine); moxifloxacin (Avelox); pimozide (Orap); procainamide (Procanbid, Pronestyl); quinidine (Quinidex); sotalol (Betapace); thioridazine; verapamil (Calan, Covera, Isoptin, Verelan); and St. John's wort. Your doctor may need to adjust the doses of your medications or observe your health closely for side effects.
Vardenafil and Alcohol
Consumption of excess alcohol can reduce your ability to experience an erection. You may be deprived of the maximum benefit of Vardenafil HCl tablets (Valif tablets). Alcohol consumption can also increase the risk of certain side effects.
Surgery and Regular Medical Tests
If you plan to have surgery or any dental procedure, inform your doctor or dentists about your course of Vardenafil tablets. In case of an emergency medical treatment, please inform the practitioner about your course of Vardenafil Hydrochloride tablets and the details of your last dose.

Side Effects of Vardenafil Tablets

The following side effects have been reported during the course of treatment with Valif tablets (Generic Vardenafil):

• Cardiovascular System- Flushed face, chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling, irregular heartbeat, Increased heart rate (tachycardia) stroke, palpitations, angina, heart attack, changes in ECG.
• Central Nervous System- feeling light-headed, fainting, headache, dizziness, seizures, sensation of spinning, temporary memory loss, nausea, sleeping problems, vertigo, anxiety.
• Skin- decreased sensation of the body to normal stimulation such as touch or pain, redness of the skin.
• Eye and ENT- sudden vision loss, vision changes, blurred vision, watery eyes, increased pressure in the eye, increased tear production changes in color vision (seeing blue tinge on objects, difficulty telling the difference between blue and green, or difficulty seeing at night), bleeding at the back of the eye, bloodshot eyes/red eyes, eye pain, double vision, abnormal sensation in the eye, ringing in your ears, sudden hearing loss, stuffy nose, nosebleeds, hoarseness.
• Gastrointestinal System- upset stomach, heartburn, disturbances of the gut such as abdominal pain, reflux, diarrhea, vomiting, gastritis, dry mouth, gastro-oesophageal reflux.
• Genitourinary System- penis erection that is painful or lasts 4 hours or longer, bleeding from the penis, blood in the semen, blood in the urine.
• Musculoskeletal System- back pain, muscle pain, increased muscle tone, muscle cramps, muscle pain or tenderness.
• Respiratory System - shortness of breath
• Hypersensitivity- swelling in your hands/ankles/feet, warmth or redness in your face/neck/chest, flu-like symptoms, hives, rash
• Miscellaneous- allergic oedema, angioedema, abnormal laboratory test results.

Vardenafil tablets During Pregnancy and Breastfeeding

Vardenafil (Valif 20 mg Tablets) is classified by the US FDA as Pregnancy Category B.
Vardenafil jelly should be used only in men. Vardenafil Tablets (Valif 20 mg Tablets) is not indicated for use in women. Women should not consume Valif tablets. There are no studies of Vardenafil use in pregnant women.
No evidence of specific potential for teratogenicity, embryotoxicity or fetotoxicity was observed in rats and rabbits that received vardenafil at up to 18 mg/kg/day during organogenesis. This dose is approximately 100 fold (rat) and 29 fold (rabbit) greater than the AUC values for unbound Vardenafil and its major metabolite in humans given the maximum recommended human dose (MRHD) of 20 mg.
Vardenafil Tablets (Valif Tablets) is not indicated for use in women. It is not known if vardenafil is excreted in human breast milk. Vardenafil was secreted into the milk of lactating rats at concentrations approximately 10-fold greater than found in the plasma.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.

Buy Generic Vardenafil Pills Online From Only $0.86 per Pill

You can buy Generic Vardenafil Tablets online from Everest Online Pharmacy at a cheap price. Valif 20 mg and 10 mg pills, manufactured by Ajanta Pharma Limited, India are supplied in a blister strip of 10 tablets. The 20 mg tablets cost only $0.86 per unit when you place an order for 500 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith. It is without a warrant of any kind, expressed or implied.

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