Seroflo Rotacaps

Seroflo Rotacaps (Fluticasone Propionate and Salmeterol Inhalation Powder) - Product Information

Seroflo Rotacaps contains a combination of two active ingredients called Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting beta2-adrenergic agonists (LABAs) which eases the symptoms of inflammation in the respiratory system of the body. Fluticasone Propionate is a corticosteroid medication which acts as a bronchodilator to relax the smooth muscles located in the airways to aid the passage of air through the lungs.
Seroflo Rotacaps are used by patients who are at least 4 years old and are diagnosed with different bronchospasm ailments such as bronchitis, emphysema, or COPD (chronic obstructive pulmonary disease).
The contents of Seroflo Rotacaps should only be administered for inhalation and not for oral purposes. When the contents of Seroflo Rotacaps are sprayed from the inhaler into the mouth, its contents are transported directly into the airways. Seroflo Rotacaps are used to prevent the occurrence of breathing difficulties and also to reduce the frequency of such incidences.
In our online pharmacy, Seroflo Rotacaps are available in the strength of 100 mcg, 250 mcg, and 500 mcg of Fluticasone Propionate, while the strength of Salmeterol is maintained at a standard 50 mcg. Seroflo Rotacaps can only be administered in a special device called the Cipla Rotahaler (Generic Handihaler).
We also have in stock Albuterol Inhaler (Asthalin 100 mcg Inhaler) which is used as oral inhalation therapy for patients diagnosed with various bronchospasm conditions such as bronchitis, emphysema, or COPD (chronic obstructive pulmonary disease).

Name of the Drug

Seroflo Rotacaps. Seroflo Rotacaps are also known as Fluticasone Propionate and Salmeterol Inhalation Powder.

Manufacturer of Seroflo Rotacaps

Fluticasone Propionate and Salmeterol Inhalation Powder, available in our online pharmacy are manufactured by Cipla Pvt. Ltd.  
Website: www.cipla.com

Active Pharmaceutical Ingredient

The active ingredients present in in Seroflo Rotacaps are Fluticasone Propionate and Salmeterol. Each Seroflo Rotacaps contains 100 mcg, 250 mcg, or 500 mcg of Fluticasone Propionate, while the strength of Salmeterol is maintained at a standard 50 mcg.

Fluticasone Propionate and Salmeterol Inhalation Powder Indications - What are Seroflo Rotacaps Used For?

Seroflo Rotacaps contains a combination of two active ingredients called Fluticasone Propionate and Salmeterol in the dosage form of a capsule. Seroflo Rotacaps are manufactured by Cipla Pvt. Ltd. in the strength of 100 mcg, 250 mcg, and 400 mcg Fluticasone Propionate, while the strength of Salmeterol is maintained at a standard 50 mcg.
Salmeterol and Fluticasone Propionate can only be administered for oral inhalation through the Generic HandiHaler inhalation device.
Seroflo Rotacaps are used as therapy in patients suffering from COPD (chronic obstructive pulmonary disease) and related breathing difficulties such as bronchitis and emphysema. Salmeterol and Fluticasone Propionate rotacaps are used by patients suffering from characteristic symptoms of chronic obstructive pulmonary disease (COPD), bronchitis and emphysema such as shortness of breath, tightness of the chest and wheezing.
Seroflo Rotacaps are a combination of corticosteroid and a long-acting beta2-agonist bronchodilator which exerts its therapeutic effect by expanding the smooth muscles located in the airways to permit relaxed breathing.

Seroflo Rotacaps Dosage - How to Use Seroflo Rotacaps?

You should use Seroflo Rotacaps exactly as suggested by your doctor. The starting dose of Seroflo Rotacaps in patients who are 12 years old and above is dependent on the severity of their asthmatic condition.
The recommended dosage of Seroflo Rotacaps in asthma patients who are at least 12 years old is one inhalation, administered twice daily (preferably in the morning and evening) with a gap of 12 hours in between both the doses.
The maximum recommended dosage of Salmeterol and Fluticasone Propionate in asthma patients is 500 mcg Fluticasone Propionate /50 mcg Salmeterol, administered twice daily. The recommended dosage of Seroflo Rotacaps in asthma patients between the ages of 4 years and 11 years is one inhalation of 100 mcg Fluticasone Propionate /50 mcg Salmeterol, administered twice daily (preferably in the morning and evening) with a gap of 12 hours in between both the doses. The recommended dosage of Seroflo Rotacaps in COPD patients who are at least 12 years old is one inhalation of 250 mcg Fluticasone Propionate /50 mcg Salmeterol, administered twice daily (preferably in the morning and evening) with a gap of 12 hours in between both the doses.
The contents of Seroflo Rotacaps should not be swallowed and should strictly only be inhaled using the special Cipla Rotahaler. While taking out one Seroflo Rotacap from the pack, tear out the foil and tap the pack to let the capsule out without touching it with your hands. Avoid cutting the foil or using any sharp object to take out the capsule. Do not take out a Seroflo Rotacap from its intact pack until you are ready to use it. If other capsules in the pack come in contact with the environment when you are removing a Seroflo Rotacap capsule for use, it must be thrown away. Do not preserve the capsule for future usage.
After removing Seroflo Rotacap from the pack, it must instantly be placed in a special inhaler device. The device will crush the capsule so that the content inside the capsule can be easily inhaled into the lungs through the mouthpiece. While using the inhalation device, make sure that you exhale gently and deeply. Avoid breathing into the mouthpiece of the inhaler while administering the Seroflo Rotacap.
Place the mouthpiece of the inhaler between your lips and try to maintain your tongue in a flat and steady position, while keeping your head straight. When you take a slow and deep breath, you should hear or feel the capsule pulsate inside the inhaler. You can hold your breath until you start to feel breathless and then slowly breathe out while keeping the lips pressed together. To ensure the usage of the whole medication from the capsule, inhale from the mouthpiece again for a second time following the same steps as before. Consult your doctor or pharmacist if you are uncertain about how to use the special inhaler device or inhale the Seroflo Rotacap.
You should clean the inhaler device at least once every month by referring to the instructions in the patient leaflet. Each inhaler device may last for a period of one year, after which it should be replaced. Use Seroflo Rotacaps at the same time every day, so that you will remember to use it regularly. Seroflo HandiHaler should be used on a regular basis without missing any doses to get the maximum therapeutic benefit from it. Do not discontinue treatment with Seroflo Rotacaps abruptly because it may result in the development of unpleasant withdrawal symptoms.
Please consult your doctor for exact dosing instructions. Seroflo Rotacaps (Generic Fluticasone Propionate and Salmeterol Inhalation Powder) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Missed Dose

If you miss your regular dose of Seroflo Rotacaps, take it as soon as you remember. You can continue your regular schedule the next day. If you remember the missed Seroflo Rotacaps the next day, take your regular dose and skip the missed dose. Do not take a double dose to compensate the missed dose of Fluticasone Propionate and Salmeterol.

Fluticasone Propionate and Salmeterol Inhalation Powder Mechanism of Action - How Does Seroflo Rotacaps Work?

Seroflo Rotacaps contain a combination of Salmeterol and Fluticasone Propionate as the active ingredient. Salmeterol is a long-acting beta2-adrenergic agonists (LABAs) which eases the symptoms of airway inflammation in the body. Fluticasone Propionate is a corticosteroid medication which acts as a bronchodilator to relax the smooth muscles located in the airways to aid the passage of air through the lungs. Regular long-term use of Seroflo Rotacaps relieve characteristic symptoms of COPD such as shortness of breath, tightness of the chest and wheezing.

Storage Instructions for Seroflo Rotacaps

Store Seroflo Rotacaps at controlled room temperature (20°C to 25°C),protected from heat, moisture, and sunlight. Excursions are permitted from 15°C to 30°C.
Retain the original packing of the medication and do not consume Seroflo Rotacaps (Salmeterol and Fluticasone Propionate Inhalation Powder) beyond its expiration date printed on the canister. Keep the pack of Salmeterol and Fluticasone Propionate Inhalation Powder away from the reach of children and pets. Do not discard Salmeterol and Fluticasone Propionate Inhalation Powder along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.

Contraindications

Seroflo Rotacaps are contraindicated in patients with a known hypersensitivity to Fluticasone Propionate or Salmeterol or any inactive ingredient present in Seroflo Rotacaps.
Seroflo Rotacaps are contraindicated in the primary treatment of status asthmaticus or other acute episodes of asthma where intensive measures are required.

Overdose

There are no data available from clinical trials on overdose with Fluticasone Propionate and Salmeterol Inhalation Powder. However data on overdose with both drugs are given below:
The signs and symptoms of Salmeterol overdose are tremor, headache and tachycardia. The preferred antidotes are cardioselective beta-blocking agents, which should be used with caution in patients with a history of bronchospasm. If Seroflo Rotacaps therapy has to be withdrawn due to overdose of the beta agonist component of the drug, provision of appropriate replacement steroid therapy should be considered. Additionally, hypokalaemia can occur and potassium replacement should be considered.
Acute: Acute inhalation of fluticasone propionate doses in excess of those recommended may lead to temporary suppression of adrenal function. This does not need emergency action as adrenal function is recovered in a few days, as verified by plasma cortisol measurements.

Warnings and Precautions to be taken when using Seroflo Rotacaps

Medical History
Before beginning the treatment with Salmeterol and Fluticasone Propionate Inhalation Powder, discuss your personal and family medical history with your doctor. Inform your doctor if you have cardiovascular, central nervous system disorders, low bone mineral density, glaucoma, cataracts, eosinophilic conditions, hypokalemia, and hyperglycemia, convulsive disorders, thyrotoxicosis, diabetes mellitus, and ketoacidosis.
Allergy
Please inform your doctor if you have an allergy or have had an allergic reaction in the past to Fluticasone Propionate or Salmeterol or any inactive ingredient in Seroflo Rotacaps. Please tell your doctor if you have any other allergies.
Salmeterol and Fluticasone Propionate Interactions
Before beginning the oral therapy of Seroflo Rotacaps, please tell your doctor about all your present medications including prescription drugs, over the counter medications, mineral supplements, herbal products, and vitamins. Salmeterol and Fluticasone Propionate Inhalation Powder are known to have drug interactions with certain other medications. Please inform your doctor if you are taking strong cytochrome P450 3A4 inhibitors (e.g., ritonavir) because it may result in the development of systemic corticosteroid and cardiovascular effects; monoamine oxidase inhibitors and tricyclic antidepressants because it may increase the side effect of salmeterol on the vascular system; beta-blockers because they may hinder bronchodilatory effects of beta-agonists and result in severe bronchospasm; diuretics because they may cause changes in electrocardiographic and/or may further deteriorate hypokalemia associated with nonpotassium-sparing diuretics.
Live Vaccinations, Surgery and Regular Medical Tests
If you plan to have live vaccinations, surgery or any dental procedure, inform your doctor, anesthetist, or dentist about your course of Seroflo Rotacaps. In case of an emergency medical treatment, please inform the practitioner about your course of Salmeterol and Fluticasone Propionate and the details of your last dose.

Side Effects of Seroflo Rotacaps

The following side effects have been reported during the course of treatment with Salmeterol and Fluticasone Propionate Inhalation Powder:

• Central Nervous System- headache
• Respiratory System- pharyngitis, upper respiratory tract infection, dysphonia, pneumonia, throat irritation, viral respiratory infections
• Musculoskeletal System- back pain, pain in joints, muscle pain
• Hypersensitivity- rash, hives, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, tightness in the chest, skin redness

Inform your doctor immediately if you experience any of these side effects. This is not an exhaustive list of all the potential side effects of Salmeterol and Fluticasone Propionate Inhalation Powder. If you develop any other medical conditions during the course of treatment with Seroflo Rotacaps, please contact your doctor immediately.

Fluticasone Propionate and Salmeterol Inhalation Powder During Pregnancy

Fluticasone Propionate and Salmeterol Inhalation Powder has been classified by the US FDA as Pregnancy Category C.
There are no adequate and well-controlled trials with Fluticasone Propionate and Salmeterol Inhalation Powder in pregnant women. Corticosteroids and beta2 -agonists have been shown to be teratogenic in laboratory animals when administered systemically at relatively low dosage levels. Because animal reproduction studies are not always predictive of human response, Seroflo Rotacaps should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Administration of Seroflo Rotacaps to pregnant women should only be considered if the expected benefit to the mother is greater than any possible risk to the foetus. The lowest effective dose of Fluticasone Propionate needed to maintain adequate asthma control should be used in the treatment of pregnant women.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.

Buy Seroflo 100 mcg, 250 mcg and 500 mcg Rotacaps Online From Only $0.31 per Capsule

You can buy Seroflo Rotacaps (Generic Fluticasone Propionate and Salmeterol Inhalation Powder) online from Everest Online Pharmacy at a cheap price. Seroflo Rotacaps manufactured by Cipla Limited, India, are available in strengths of 100 (100 mcg of Fluticasone Propionate and Salmeterol 50 mcg), 250 (250 mcg of Fluticasone Propionate and Salmeterol 50 mcg) and 500 (500 mcg of Fluticasone Propionate and Salmeterol 50 mcg) and supplied as capsules in a bottle with 30 capsules. The 100 mcg Seroflo rotacaps cost only $0.31 per unit when you place an order for 360 capsules.

Disclaimer

The above information is provided to the best of our knowledge and in good faith. It is without a warrant of any kind, expressed or implied.

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