Risedronate Sodium Tablets

Risofos Tablets (Generic Risedronate Sodium 35 mg and 150 mg) - Product Information

Risofos tablets are used for the treatment and prevention of osteoporosis that develops as a result of different medical conditions. Risofos tablets contain Risedronate as the active ingredient, which belongs to the bisphosphonate class of medications.
Risedronate Sodium tablets help to prevent bone malfunction and increases bone density (thickness), thus helping in the maintenance of stronger bones. Risedronate Sodium tablets (Risofos) are prescribed as oral therapy for the treatment of osteoporosis in post-menopausal women. Risedronate Sodium tablets are also useful for increasing the bone density in adults who are on an extended corticosteroids treatment.
Risedronate tablets are effectively used to increase the bone mass in men suffering from osteoporosis. Patients suffering from osteoporosis develop a reduced bone strength over time, thus increasing the risk of fractures. Risedronate Sodium tablets improve and strengthen the bones, consequently decreasing the possibility of fracture occurrences. Generic Risedronate Sodium tablets are also recommended as therapy for the treatment of Paget’s disease in adults.
In our online pharmacy, Risofos tablets are available in the strength of 35 mg, 75 mg and 150 mg of Risedronate.
We also have in stock Osteofos Tablets (Alendronate Sodium) which are prescribed for the treatment and prevention of osteoporosis that develops as a result of different medical conditions.

Name of the Drug

Risofos tablets.

Manufacturer of Risofos Tablets

Risofos tablets, available in our online pharmacy are manufactured by Cipla Ltd. Risofos tablets are also known as Generic Risedronate.  
Website: www.cipla.com

Active Pharmaceutical Ingredient

The active ingredient present in Risofos tablets is Risedronate Sodium. Each Risofos tablet contains either 35 mg, 75 mg or 150 mg of Risedronate Sodium.
The inactive ingredients present in Risedronate Sodium pills are colloidal silicon dioxide, lactose monohydrate, magnesium stearate, pregelatinized starch, sodium stearyl fumarate, starch, D&C Yellow No. 10 Lake, hydroxypropyl methylcellulose, iron oxide yellow, polyethylene glycol, polysorbate, and titanium dioxide.

What are Risofos Tablets Used For?

Risofos tablets, manufactured by Cipla Ltd., contain Risedronate Sodium which belong to a class of medications known as bisphosphonates. Risofos tablets are used for the treatment and prevention of the bone disease called osteoporosis that arises as a result of different conditions in postmenopausal women.
Risedronate Sodium tablets are typically administered as oral therapy to increase the bone mass in men who suffer from osteoporosis.
Patients suffering from osteoporosis develop brittle and fragile bones due to decreased bone strength. Such bones become thin are more prone to the occurrences of bone breakage and fractures. Risedronate sodium are effectively used to decrease the rate of bone loss in patients with osteoporosis by increasing the bone thickness.
Risedronate Sodium tablets are also beneficial for the treatment of Paget's disease in adults, who have developed weak and deformed bones and as a result are prone to fractures and breakage. Patients who have developed Paget's disease, suffer from excessive pain which aggravates during night-time. Treatment with Risedronate Sodium tablets helps to relieve this extreme pain.
Risofos tablets is usually recommended for the prevention and treatment of osteoporosis that has progressed as a result of extended systemic glucocorticoid treatment in adults.

Risofos Dosage - How to Take Risedronate Sodium Tablets?

You should use Risofos tablets exactly as recommended by your doctor. Your doctor may suggest a dosage of Risedronate tablets depending on the severity of medical condition, body weight, other medical conditions, and current medications.
Risedronate Sodium tablets should be swallowed with a glass of water, at least 30 minutes prior to the first food or drink of the day (excluding water). To enable the uninterrupted delivery of the drug to the stomach, the patient should swallow Risedronate Sodium tablets while standing in an upright position. After swallowing Risedronate Sodium tablets, continue to maintain the upright position for up to 30 minutes after administration of Risedronate Sodium tablets and until your first meal for the day. Try to maintain a regular schedule for the medication such that you take Generic Risedronate Sodium tablets at the same time every day, to get the maximum benefit of the medication.
You may be instructed to not take more than 2 Risedronate Sodium tablets in a month. Your doctor may alter the dosage of Risofos tablets and dosage period depending on the type and severity of your medical condition and your response to treatment. The recommended dosage of Risedronate Sodium tablets for the treatment of osteoporosis in postmenopausal women is 35 mg once a week. The suggested dose for the prevention of osteoporosis in postmenopausal women is 35 mg once a week administered orally.
For men suffering from osteoporosis, the optimal dose is 35 mg once a week, administered orally. Patients diagnosed with glucocorticoid-induced osteoporosis should ideally be administered a single 35 mg Risedronate Sodium tablet, once a week. In patients suffering from Paget’s disease, the recommended daily dose is 30 mg for a period of 2 months.
It is imperative that you complete the recommended course of treatment with Risedronate tablets even if you feel better. Make it a point to visit your doctor regularly during the course of Risedronate Sodium tablets to monitor your progress.
Please consult your doctor for exact dosing instructions. tablets (Generic tablets) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Missed Dose

If you miss your regular dose of Risofos tablets (Generic Risedronate Sodium tablets), take it as soon as you remember. You can continue you regular schedule the next day. However, you should make sure that you have not eaten or drank anything two hours prior to the time of the administration of the drug.
If you remember the missed Risedronate tablets the next day or during the bedtime at night, take your regular dose and skip the missed dose. Do not take a double dose to compensate the missed dose.

Risofos Mechanism of Action – How Does Risedronate Work?

Risofos (Generic Risedronate Sodium tablets) is a bisphosphonate medication which slows down the process of bone loss. The structure and dimensions of the human bone constantly undergoes changes in shape and form. The structure of the bone is dependent on the storage of calcium and phosphorous minerals in the form of a protein network. The human bone consists of specialized cells called osteoblasts and osteoclasts, which are responsible for the continuous accumulation and elimination of calcium and phosphorous minerals in the bone. Osteoclasts regulate the breakdown of old bone and osteoblasts are responsible for the formation of new bone.
Women undergoing the phase of menopause experience a decrease in the blood levels of the female hormone called oestrogen. This estrogen decline results in an increase in the rate of bone breakdown by the osteoclasts, eventually leading to a loss in bone density. The rate of bone loss is especially high during the first ten years immediately following menopause, which may lead to the advancement of osteoporosis - a medical condition characterized by weak and brittle bones which are prone to fractures.
Risedronate exerts its mechanism of action by forming a strong attachment to the bone structure, thus effectively inhibiting the removal of calcium performed by the osteoclasts. This osteoclast inhibition allows Risedronate to prevent bone breakdown by increasing the thickness of bones i.e. bone mineral density and results in stronger bones which are less prone to damage.

Storage Instructions for Risofos Tablets

Store Risofos tablets at controlled room temperature (20°C to 25°C),protected from heat, moisture, and sunlight. Excursions are permitted from 15°C to 30°C.
Retain the original packing of the medication and do not consume Risedronate Sodium tablets (Risofos) beyond its expiration date printed on the blister pack. Keep the pack of Risofos tablets away from the reach of children and pets. Do not discard Risedronate tablets along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.

Contraindications

The treatment with Risedronate Sodium tablets is contraindicated in patients who are allergic to Risedronate Sodium or any inactive ingredients present in Risofos tablets (Generic Risedronate), who cannot stand in an upright position for at least 30 minutes, who have low blood calcium levels, abnormalities of the esophagus (such as stricture and achalasia) that delay esophageal emptying or who have severe kidney impairment.

Overdose

Decreases in serum calcium and phosphorus following substantial overdose may be expected in some patients. Signs and symptoms of hypocalcemia may also occur in some of these patients.
While milk or antacids containing calcium may be given to bind risedronate sodium immediate- release and reduce absorption of the drug, the impact of this intervention for risedronate sodium delayed-release tablets has not been evaluated.
In cases of substantial overdose, gastric lavage may be considered to remove unabsorbed drug. Standard procedures that are effective for treating hypocalcemia, including the administration of calcium intravenously, would be expected to restore physiologic amounts of ionized calcium and to relieve signs and symptoms of hypocalcemia.

Warnings and Precautions to be taken when using Risofos Tablets

Medical History
Before beginning the treatment with Risofos tablets (Generic Risedronate Sodium tablets), discuss your personal and family medical history with your doctor. Inform your doctor if you have hypocalcemia (low blood calcium levels), swallowing difficulties, kidney problems, failure to sit upright for a minimum of 30 minutes, active upper GI problems (such as Barrett esophagus, dysphagia, other esophageal diseases, gastritis, duodenitis, ulcers), gastrointestinal problems, risk factors for jaw osteonecrosis, parathyroid gland disorders, Vitamin D deficiency, rare hereditary problems (such as galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption), cancer, any type of infection.
Risedronate Interactions
Before beginning the oral therapy of Risedronate Sodium tablets, please inform your doctor of all your current medications including prescription drugs, over the counter medications, mineral supplements, herbal products, and vitamins. Risedronate Sodium is known to have interactions with aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); cancer chemotherapy; or oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone), H2 blocker such as cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), and ranitidine (Zantac), systemic angiogenesis inhibitors (axitinib, bevacizumab, lenalidomide, pazopanib, regorafenib, vandetanib) or a proton pump inhibitor such as esomeprazole (Nexium), lansoprazole (Prilosec), omeprazole (Prevacid, Zegarid), pantoprazole (Protonix), and rabeprazole (AcipHex). Certain medications are known to reduce the efficacy of Risedronate Sodium tablets. Such medications should not be administered two hours prior to the administration of Risedronate Sodium tablets. Some of such medication are antacids (aluminum hydroxide, calcium carbonate, magnesium hydroxide), calcium and iron supplements, laxatives that contain magnesium, multivitamins which contain calcium, iron, magnesium, or zinc minerals. Concurrent administration of aminoglycoside antibiotics such as amikacin, gentamicin, and tobramycin can result in low blood calcium levels.
Risedronate Sodium tablets - Driving and Other Activities


Risedronate Sodium tablets may make you light-headed or impair your vision. Avoid activities such as driving, using machinery, or performing any activity that requires complete vigilance or perfect vision until you are sure about your safety.
Surgery and Regular Medical Tests
If you plan to have lab tests, surgery or any dental procedure, inform your doctor or dentist about your course of Risofos tablets (Generic Risedronate Sodium tablets). In case of an emergency medical treatment, please inform the practitioner about your course of Risedronate tablets and the details of your last dose.
Calcium and Vitamin D
Calcium and vitamin D are required for healthy bone growth and good strength. If the levels of calcium and Vitamin D are insufficient in your diet, you may be instructed to take calcium or vitamin D supplements to achieve the best therapeutic effect of Risedronate Sodium tablets. Before beginning your course of Risedronate Sodium tablets, your doctor may perform certain medical tests to check if you have calcium or vitamin D deficiency.

Side Effects of Risofos Tablets

The following side effects have been reported during the course of treatment with Risofos tablets (Generic Risedronate Sodium tablets):

• Central Nervous System- dizziness, headache.
• Cardiovascular System- chest pain.
• Eye and ENT- difficult or painful swallowing, sensitivity to light, vision changes, unusual eye pain or redness, severe or persistent sore throat.
• Gastrointestinal System- abdominal pain, dyspepsia, constipation, diarrhea, gas, mild stomach pain, nausea, coughing or vomiting blood, severe heartburn.
• Genitourinary System- black or tarry stools, painful or difficult urination.
• Musculoskeletal System - back pain, arthralgia, joint pain, muscle pain, bone pain.
• Hypersensitivity- rash, hives, itching, breathing difficulties, tightness in chest, swelling of the mouth/face/lips/tongue, mouth sores, swelling of arms and legs, selling or pain in jaw area.
• General- anaphylactic reaction, hair loss.

 Inform your doctor immediately if you experience any of these side effects. This is not a comprehensive list of all the possible side effects of Risofos tablets (Generic Risedronate Sodium tablets). If you develop any other medical conditions during the course of treatment with Risofos tablets, please consult your doctor immediately. 

Risedronate Sodium (Risofos Tablets) – Birth-control, Pregnancy and Breastfeeding

Risedronate Sodium has been classified by the US FDA as Pregnancy Category C.
It is generally not known to affect the growth of a fetus. The risk of administering Risedronate Sodium tablets to pregnant women should be discussed with the doctor. Risedronate is not known to be secreted through breast milk. Women planning to start a family and lactating mothers are generally instructed to check with their doctor if they are undergoing a course of Generic Risedronate Sodium tablets.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.

Buy Generic Risedronate Sodium 35 mg & 150 mg (Risofos Tablets) Pills Online From Only $3.35 per Pill

You can buy Generic Risedronate Sodium tablets online from Everest Online Pharmacy at a cheap price. Risofos 35 mg and 150 mg pills, manufactured by Cipla Limited, India, are supplied in a blister strip of 1 or 4 tablets. The 35 mg tablets cost only $3.35 per unit when you place an order for 40 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith. It is without a warrant of any kind, expressed or implied.

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