Isotretinoin Capsules

US patients please note:
Isotretinoin can be dispensed only by a pharmacy registered and activated with iPLEDGE. We are not registered with iPLEDGE. Patients and prescribers must be registered as well.

Please contact us for details, if you are a patient not residing in the USA.

Isotretinoin Capsules (Isotroin Capsules) - Product Information

Isotretinoin is a derivative of vitamin A which are orally administered to effectively treat acne-afflicted skin by decreasing the amount of oil secreted by the sebaceous glands (oil glands) of the skin.
It is used for the treatment of moderate to severe acne conditions which are unresponsive to other therapies.
Isotroin capsules of strengths 5 mg, 10 mg and 20 mg are available in our online pharmacy.
We also have in stock Azelaic Acid Cream (Aziderm 10% and 20% Cream) which is topically administered for the treatment of bacterial skin infection such as acne and rosacea.

Name of the Drug

The generic name of Isotroin is Isotretinoin.
Isotretinoin is also available under brand names that include Tretiva, Absorica, Accutane, Amnesteem, Claravis, and Sotret.

Manufacturer of Isotroin Capsules

Isotroin capsules are manufactured by Cipla Limited, India  
Website: www.cipla.com

Active Pharmaceutical Ingredient

The active ingredient present in Isotroin Capsules is Isotretinoin.
Isotroin 10 capsules contains a strength of 10 mg Isotretinoin while Isotroin 20 capsules contains a strength of 20 mg Isotretinoin.
The other inactive ingredients present in Isotroin capsules are beeswax, black iron oxide, hydrogenated hydrolyzed starch, gelatin, glycerol, hydrogenated soybean oil, propylene glycol, red iron oxide, mannitol, partially hydrogenated soybean oil, shellac, sorbitol, soybean oil, and titanium dioxide.

What are Isotretinoin Capsules Used For?

Isotretinoin capsules are used for the effective treatment of severe acne conditions such as severe nodular acne (cystic acne) which were unresponsive to other medications (antibiotics such as benzoyl peroxide or clindamycin which are topical medications and tetracycline or minocycline which are oral medications.)
Isotroin capsules are also shown to have certain benefits towards the treatment of cutaneous T-cell lymphoma, psoriasis, hair follicle inflammation due to gram-negative bacteria medications, and nodular rosacea.

Isotroin Capsules - Dosage

Isotretinoin capsules should be administered exactly as recommended by the doctor. Do not alter the dosage of the medication or the dosage period without consulting the prescriber. Usually Isotroin capsules are administered twice a day after a meal, unless you are given any other advice by the doctor.
Isotretinoin capsules should be swallowed and not sucked or chewed. Swallow Isotroin capsules as quickly as possible along with a glass of water or milk to avoid irritation caused by the melting of the Isotretinoin capsule in the food pipe.
A single course of Isotretinoin capsules lasts for a period of 15 to 20 weeks which is an adequate period of time to achieve complete and lasting results of treatment. Depending on the severity of your medical condition and your response to treatment, your doctor will alter your dosage to achieve the best possible result. If your response to the treatment is satisfactory, your doctor may shorten the dosage period from the standard 15 to 20 weeks.
After the completion of a single treatment course of Isotroin capsules, there should be a “rest period” of at least two months, when no drugs are administered. The acne may continue to be cured even without the medication during this period. After the rest period, if the acne conditions shows little improvement, your doctor may follow it up with a second course of Isotretinoin capsules.
To ensure the safety of the medication on your system, your doctor may advise you to perform occasional blood tests and liver function tests.
Please consult your doctor for exact dosing instructions. tablets (Generic tablets) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Missed Dose

If you fail to take your regular Isotroin capsule dose on time, take it whenever you remember during the day. If you remember the next day, skip the missed dose and take your scheduled dose.
Do not take a double dose in a single day to compensate the missed dose.

Isotroin Mechanism of Action – How Does Isotretinoin Work?

Isotretinoin belongs to a class of drugs known as retinoid. Retinoids are commonly used for the treatment of skin problems. Isotretinoinworks by suppressing the production of skin oil (sebum) by the sebaceous glands. Higher sebum production results in the manifestation of severe acne. Isotroin capsules reduces the size of the sebaceous glands, alter the characteristics of the skin oil and prevent the unusual hardening of skin.

Storage

Store Isotretinoin capsules at controlled room temperature (20°C to 25°C). Excursions are permitted from 15°C to 30°C. Keep the pack of Isotroin capsules protected from heat, light, and moisture.
Do not consume Isotroin capsules after its expiration date printed on the blister pack. Do not dispose Isotretinoin capsules along with other domestic waste. Isotroin capsules should be discarded in an environment-friendly manner. Consult your pharmacist about the proper disposal techniques.

Contraindications

Isotroin is contraindicated in patients who are hypersensitive to this medication or to any of its components. Isotroin should not be given to patients who are sensitive to parabens, which are used as preservatives in the gelatin capsule.
Isotroin can cause fetal harm when administered to a pregnant woman. Major congenital malformations, spontaneous abortions, and premature births have been documented following pregnancy exposure to isotretinoin in any amount and even for short periods of time.
Isotroin is contraindicated in females who are or may become pregnant.

Overdose

In humans, Isotretinoin overdosage has been associated with vomiting, facial flushing, cheilosis, abdominal pain, headache, dizziness, and ataxia. These symptoms quickly resolve without apparent residual effects.
Isotretinoin (Isotroin capsules) causes serious birth defects at any dosage.

Warnings and Precautions to be taken when using Isotretinoin Capsules

Medical History
Before you begin the course of Isotretinoin capsules, let your doctor know about your medical history. Make sure that your doctor is aware any personal or family history of depression or mental illness, obesity, heart disease, high cholesterol or triglycerides, osteoporosis or other bone loss disorders, intestinal disorder (inflammatory bowel disease, ulcerative colitis, or Crohn's disease), diabetes, asthma, eating disorder (anorexia nervosa), liver disease, alcohol abuse, pancreatitis, and vitamin A poisoning.
Allergy
Let your doctor know if you are allergic to Isotretinoin, parabens, vitamin A-related drugs (tretinoin), or any other inactive ingredients present in the Isotroin capsules.
Isotroin Interactions
Inform your doctor about all your current medications such as prescription, over-the-counter drugs, vitamins, dietary supplements, and herbal products. Avoid starting a new medication without informing your doctor. Medications containing acitretin, birth control pills (estrogen/progestin), carbamazepine, corticosteroids (prednisone), multivitamins with vitamin A, porfimer, St. John's wort, exfoliants, keratolytics, antibiotics (doxycycline, minocycline, tetracycline), tigecycline, and tretinoin are known to interact with Isotretinoin capsules. Consult your doctor if you are using any such medications and discuss the implications of these medications on the Isotroin treatment. Your doctor will advise you about the future course of action.
General Precautions During Isotroin Treatment
Avoid blood donation during the course of Isotretinoin capsules and for at least 30 days after you discontinue the treatment. Donated blood containing any level of Isotretinoin that is later transferred to pregnant woman could result in birth defects in the baby. Do not use wax hair removers or have dermabrasion or laser skin treatments during the course of Isotroin capsules and for at least 6 months after the treatment period has elapsed. Such procedures may result in scarring of skin.
Avoid contact with sunlight or artificial UV rays (sunlamps or tanning beds). Isotretinoin treatment can make your skin more vulnerable sunburn from exposure to sunlight and sunburn.
Isotretinoin treatment may result in bone loss. As a result, participating in high impact sports (e.g., football, basketball, soccer, tennis) may cause bone complications, leading to a higher risk of broken bones.
Isotretinoin Treatment in Children
Isotretinoin capsules should be administered to children after careful consideration and consultation because they may be more sensitive to the side effects of Isotretinoin such as its effects on bones. In growing children, Isotretinoin treatment may halt the normal growth (epiphyseal plate closure). Consult your doctor before administering Isotretinoin capsules to children.
Isotretinoin Treatment in Senior Citizens
Similarly, Isotretinoin capsules should be administered to senior citizens after careful consideration and consultation because they may be more sensitive to the side effects of Isotretinoin such as back/joint/muscle pain.
Alcohol
Avoid the use of alcohol during the course of Isotretinoin capsules because your risk of contracting certain side effects (e.g., pancreatitis) may be increased due to the medication.
Isotretinoin and Birth Defects
Isotretinoin capsules are contraindicated in pregnant women because of its severe birth defects such as deformed ears, eyes, face, skull, heart, and brain. Pregnant women or women who become pregnant during the course of Isotretinoin treatment should absolutely avoid the administration of Isotretinoin capsules.
Female Patients, Family Planning, and Pregnancy
Women of childbearing age should use 2 functional forms of birth control at least 1 month before starting Isotretinoin treatment, during Isotretinoin treatment, and for 1 month after the Isotretinoin treatment period has elapsed. Your health care provider should perform pregnancy tests at regular intervals during your Isotroin treatment period.
Women should qualify a negative pregnancy test 30 days before the Isotretinoin medication period. A pregnancy test is also mandatory before each prescription is replenished, at the end of Isotretinoin treatment, and again 30 days after the treatment period has elapsed.
Breast-feeding mothers should consult their doctors before starting the Isotretinoin treatment.
Driving and Operating Machinery
Isotretinoin may weaken your vision, particularly at night. Be alert if you drive or perform any activity such as operating heavy machinery which requires you to see clearly. Avoid driving unless your vision has returned to normal or if you feel tired or light-headed while taking Isotretinoin capsules.
Diabetes Patients
Blood sugar may undergo certain alterations during the treatment with Isotroin capsules. You should strictly monitor your blood sugar levels and ask your health care provider before adjusting the dose of your diabetes medicine.

Side Effects of Isotroin Capsules

Consult your doctor if you develop any of these side effects during Isotroin treatment: abnormal hair growth; hair loss; abnormal skin sensations; bleeding and redness or swelling of the gums; changes in menstrual flow; decreased tolerance to contact lenses; dizziness; dry eyes, lips, and mouth; minor swelling of the eyelids or lips; dry nose that may lead to nosebleeds; dry, crusty, or peeling skin; fatigue; flushing; upset stomach; general body discomfort; headache; itching; lack of energy; nervousness; respiratory tract infection; insomnia; sweating; temporary worsening of acne; voice changes.
Inform your doctor immediately if you develop these severe side effects during Isotroin treatment: severe allergic reactions (rash; hives; breathing difficulties; tightness in the chest; swelling of the mouth, face, lips, or tongue); mental or mood swings; bizarre, aggressive, or violent behavior; hallucinations; concentration problems; thoughts of suicide; depression; bowel pain; dark urine; difficult or painful swallowing; difficulty in walking; tingling feeling in the skin; excessive thirst or urination; fainting; fast heartbeat; fever; fractured or weak bones; hearing loss or ringing in the ears; increased pressure in the brain (pressure in the eye; nausea; vision changes; vomiting); joint or back pain; leg swelling; muscle weakness with or without pain; new or worsening heartburn; rectal bleeding; red patches or bruises on the legs; seizures; severe diarrhea; severe headache; pancreatitis; skin infection; incoherent speech; stomach pain or tenderness; stroke; severe birth defects; stunted growth in children; severe sunburn; swelling of the pancreas (fever; increased heartbeat; nausea; stomach tenderness; vomiting); swollen glands; tightness in the lungs; vision changes; vomiting; weakness; jaundice (yellowing of the skin or eyes).
This is not a comprehensive list of all the possible side effects. If you develop any other serious or lethal medical condition during the treatment of Isotroin capsules, seek emergency help immediately.

Isotretinoin  (Isotroin Capsules) During Pregnancy

Isotretinoin (Isotroin Capsules) has been classified by the US FDA as Pregnancy Category X. Isotroin capsules is contraindicated during pregnancy because Isotretinoin can cause can cause fetal harm when administered to a pregnant woman. There is an increased risk of major congenital malformations, spontaneous abortions, and premature births following Isotretinoin exposure during pregnancy in humans.
If this drug is used during pregnancy, or if the patient becomes pregnant while taking the drug, the patient should be apprised of the potential hazard to a fetus.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.

Isotroin Capsules - Nursing Considerations

It is not known whether Isotretinoin (Isotroin Capsules) is present in human milk. Because many drugs are present in human milk and because of the potential for serious adverse reactions in nursing infants from Isotroin capsules, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Do not use this medication without telling your doctor if you are breast-feeding a baby.

Buy Isotretinoin 5 mg, 10 mg and 20 mg Capsules Online From Only $0.62 per Pill

You can buy Isotretinoin capsules online from Everest Online Pharmacy at a cheap price. Isotroin capsules (Generic Isotretinoin) manufactured by Cipla Ltd., India are available in strengths of 5 mg, 10 mg and 20 mg pills, and are supplied in a box with 10 or 15 soft gel capsules. The 5 mg soft gel capsules cost only $0.62 per unit when you place an order for 300 capsules.

Disclaimer

The above information is provided to the best of our knowledge and in good faith. It is without a warrant of any kind, expressed or implied.

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