Hyoscine Butylbromide And Paracetamol Tablets

Hyoscine Butylbromide And Paracetamol Tablets (Hyocimax Plus Tablets) - Product Information

Hyocimax Plus tablets are antispasmodic medications which contain Hyoscine Butylbromide and Paracetamol (Acetaminophen) as the active ingredients.
Hyocimax Plus tablets are prescribed as oral therapy for the effective treatment of abdominal pain or cramps which occurs due to the muscle spasm of the digestive or urinary system (stomach, intestines or bladder). . Hyoscine Butylbromide tablets is also effective against symptoms of irritable bowel syndrome and diverticular disease such as bloating and pain associated with spasms.
This special combination of Hyoscine Butylbromide and Paracetamol (Hyocimax Plus) allows cramped muscles to relax and simultaneously delivers fast relief from pain
In our online pharmacy, Hyocimax Plus tablets are available in the strength of 10 mg of Hyoscine Butylbromide and 500 mg of Paracetamol.
We also have in stock Dimenhydrinate Tablets (Gravol) which are beneficial for the treatment and prevention of the symptoms of motion sickness such as vomiting, dizziness and the treatment and prevention of nausea and vomiting which occur post medical procedures such as chemotherapy, radiation, and surgery.

Name of the Drug

Hyocimax Plus tablets.
Hyocimax tablets are also available under different brand names such as Buscopan Plus.

Manufacturer of Hyocimax Tablets

Hyocimax Plus tablets, available in our online pharmacy are manufactured by Acme Pharmaceuticals, marketed by German Remedies (Zydus Healthcare)  
Website: www.zyduscadila.com

Active Pharmaceutical Ingredient

The active ingredients present in Hyocimax Plus tablets are Hyoscine Butylbromide and Paracetamol (Acetaminophen). Each Hyocimax Plus tablet contains 10 mg of Hyoscine Butylbromide and 500 mg of Paracetamol.

Uses of Hyocimax Plus (Hyoscine Butylbromide 10mg & Acetaminophen 500mg) Tablets

Hyocimax Plus tablets, manufactured by Acme Pharmaceuticals (Cadila Healthcare), are commonly used as oral therapy for the treatment of pain and cramps that occur in the stomach, intestine, and urinary bladder. Hyoscine Butylbromide and Paracetamol tablets are also used for the treatment of symptoms such as pain and spasms associated with a common intestinal condition known as Irritable Bowel Syndrome (IBS).

Hyocimax Plus Dosage - How to Take Hyoscine Butylbromide Tablets?

Generic Hyoscine Butylbromide and Paracetamol tablets should be administered exactly as suggested by your doctor. Your doctor may recommend a dosage of Hyocimax tablets depending on your age, gender, medical requirement, body weight, other medical conditions, and current medications. Hyocimax Plus tablets should be taken with a glass of water. You should be systematic about the daily schedule for the medication such that you take Hyocimax Plus tablets at the same time every day, to get the maximum benefit of the medication.
For adults, the recommended dose is 1 to 2 tablets up to 3 times daily, with a maximum of 6 tablets per day. Children aged 12 and over may use Buscopan Plus, but it is not suitable for children under 12. Tablets should be swallowed whole with water.
Hyoscine Butylbromide and Paracetamol (Hyocimax Plus) should not be taken over prolonged period of time (for more than 3 days) without a prescription from the physician.
Do not stop the treatment temporarily even if you feel that your symptoms have cleared because Hyocimax tablets can only help to control your symptoms but it does not cure the medical condition.
Please consult your doctor for exact dosing instructions. Hyocimax Plus tablets (Generic Hyoscine Butylbromide and Paracetamol tablets) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Missed Dose

If you miss your regular dose of Hyocimax Plus tablets, take it as soon as you remember. You can continue your regular schedule the next day. If you remember the missed Hyoscine Butylbromide and Paracetamol tablets the next day, take your regular dose and skip the missed dose.
Do not take a double dose to compensate the missed dose of Hyoscine Butylbromide tablets.

Hyoscine Butylbromide and Paracetamol Tablets Mechanism of Action – How Does Hyocimax Plus Work?

Buscopan Plus tablets contain two active ingredients, Hyoscine Butylbromide and Paracetamol, which work together through a dual mechanism of action to relieve strong abdominal pain caused by cramps and spasms.
Hyoscine Butylbromide (Antispasmodic)
Hyoscine butylbromide works as an antispasmodic agent primarily by:
Relaxing smooth muscles: It acts on the smooth muscles of the stomach, intestines (gut), and the genito-urinary tract.
Blocking nerve signals: It is an anticholinergic medication that binds to muscarinic receptors on these smooth muscle cells, blocking the neurotransmitter acetylcholine from activating them. This prevents the excessive contractions and spasms, thereby relieving the associated pain, bloating, and discomfort.
Localized action: As a quaternary ammonium compound, it is poorly absorbed into the bloodstream and does not cross the blood-brain barrier, which minimizes central nervous system side effects like drowsiness. Its effect is localized to the abdominal and pelvic areas.

Paracetamol (Analgesic/Pain Reliever)
Paracetamol complements the action of hyoscine butylbromide by providing general pain relief:
Increasing the pain threshold:It works in the central nervous system to block the release of certain chemical messengers (prostaglandins) that are responsible for causing pain and fever.
Analgesic properties:
It acts independently as a pain reliever to address the painful sensation associated with the cramps, which may not be fully resolved by muscle relaxation alone.
In summary, the combination in Buscopan Plus targets both the cause of the pain (muscle spasms) and the sensation of the pain (via general pain relief), providing dual-action relief.

Storage

Store the pack of Hyoscine Butylbromide and Paracetamol tablets at controlled room temperature (20°C to 25°C), protected from heat, moisture, and sunlight. Excursions permitted from 15°C to 30°C.
Retain the original packing of the medication and do not consume Hyoscine Butylbromide and Paracetamol tablets (Hyocimax Plus) beyond its expiration date printed on the blister pack. Keep the pack of Hyocimax Plus tablets away from the reach of children and pets. Do not discard Hyocimax Plus tablets along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.

Contraindications

Hyocimax Plus tablets are contraindicated in patients with a known hypersensitivity to Hyoscine Butylbromide, Paracetamol or any inactive ingredient present in Hyocimax tablets.
Hyoscine Butylbromide tablets should not be administered in children below the age of 12 years. Hyocimax Plus tablets are also contraindicated in patients who are suffering from myasthenia gravis, megacolon, certain bowel obstructions (obstructive ileus, megacolon), severe liver problems and narrow angle glaucoma.

Overdose

If you administer an overdose of Hyoscine Butylbromide and Paracetamol tablets (Hyocimax Plus tablets), please seek emergency medical help immediately and discontinue the course of medication. Signs of overdose of Hyoscine Butylbromide may include pallor, nausea, vomiting, anorexia and abdominal pain. Patients may then experience a temporary subjective improvement but mild abdominal pain possibly indicative of liver damage may persist.
A single dose of paracetamol of approximately 6 g or more in adults or 140 mg/kg in children may cause hepatocellular necrosis. This may lead to complete irreversible necrosis and subsequently to hepatocellular insufficiency, metabolic acidosis and encephalopathy, which may in turn progress to coma and death. Concurrent rises in liver transaminases (AST, ALT), lactate dehydrogenase and bilirubin and an increase in prothrombin time, occurring 12 to 48 hours after ingestion, have been observed. Clinical symptoms of liver damage are normally apparent after 2 days and reach a maximum after 4-6 days.
Acute renal failure with acute tubular necrosis may develop even in the absence of severe liver damage.
Other non-hepatic symptoms such as myocardial abnormalities and pancreatitis have also been reported to occur after paracetamol overdosage.
Treatment: If required, parasympathomimetic drugs should be administered.
Ophthalmological advice should be sought urgently in cases of glaucoma. Cardiovascular complications should be treated according to usual therapeutic principles. In case of respiratory paralysis: intubation, artificial respiration should be considered.
Catherisation may be required for urinary retention.
In addition, appropriate supportive measures should be used as required. Where paracetamol intoxication is suspected, intravenous administration of SH group donators such as N-acetylcysteine within the first 10 hours after ingestion is indicated. Although N-acetylcysteine is most effective if initiated within this period, it can still offer some degree of protection if given as late as 48 hours after ingestion; in this case, it is taken for longer. The plasma concentration of paracetamol can be decreased by dialysis. Determinations of the plasma concentration of paracetamol are recommended.
Further measures will depend on the severity, nature and course of clinical symptoms of paracetamol intoxication and should follow standard intensive care protocols.

Warnings and Precautions to be taken when using Hyoscine Butylbromide and Paracetamol Tablets (Hyocimax Plus Tablets)

Medical History
Before beginning the treatment with Hyocimax Plus tablets (Generic Hyoscine Butylbromide and Paracetamol tablets), discuss your personal and family medical history with your doctor. Inform your doctor if you are pregnant or breast-feeding, have prostate problems, other digestive system problems (reflux disease, diarrhoea, ulcerative colitis, or severe constipation), high blood pressure, recently had a heart attack, glaucoma, tachycardia (a fast heart rate), heart disease, an abnormal heart rhythm, heart failure, or mitral stenosis (a heart valve problem), Down's syndrome, are less than 12 years old or over 65 years old, autonomic neuropathy, megacolon, ulcerative colitis, overactive thyroid gland (hyperthyroidism), myasthenia gravis, constipation, fever, rare hereditary problems (fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency)
In case severe, unexplained abdominal pain persists or worsens, or occurs together with symptoms like fever, nausea, vomiting, changes in bowel movements, abdominal tenderness, decreased blood pressure, fainting or blood in stool, medical advice should immediately be sought.
To prevent overdosing, it should be ensured that any other drugs taken concurrently do not contain paracetamol, one of the active components of Hyoscine Butylbromide and Paracetamol Tablets (Hyocimax Plus Tablets).
Liver damage may result if the recommended dosage for paracetamol is exceeded.
Hyoscine Butylbromide and Paracetamol Tablets (Hyocimax Plus Tablets) should be used with caution in: glucose-6-phosphate-dehydrogenase deficiency, hepatic dysfunction (e.g. due to chronic alcohol abuse, hepatitis), impaired renal function, Gilbert's syndrome, and hepatocellular insufficiency (Child-Pugh A/B).
In such cases Hyoscine Butylbromide and Paracetamol Tablets (Hyocimax Plus Tablets) should only be used under medical supervision and, if necessary, the dose reduced or the intervals between the individual administrations prolonged.
The blood count and renal and liver function should be monitored after prolonged use.
Extensive use of analgesics, especially at high doses, may induce headaches that must not be treated with increased doses of the drug. Severe acute hypersensitivity reactions (e.g. anaphylactic shock) are very infrequently observed. Treatment must be discontinued at the first signs of a hypersensitivity reaction following the administration of Hyoscine Butylbromide and Paracetamol Tablets (Hyocimax Plus Tablets).
Abrupt discontinuation of analgesic after prolonged use at high doses may induce withdrawal symptoms (e.g. headache, tiredness, nervousness), that typically resolve within few days. Reintake of analgesics should depend upon physician's advice, and withdrawal symptoms abated.
Hyoscine Butylbromide and Paracetamol Tablets (Hyocimax Plus Tablets) should not be taken for more than 3 days unless directed by a physician. The patient should be instructed to seek medical advice, if pain persists or gets worse, if new symptoms occur, or if redness or swelling is present because these could be signs of a serious condition.
Because of the potential risk of anticholinergic complications, caution should be used in patients prone to narrow angle glaucoma as well as in patients susceptible to intestinal or urinary outlet obstructions and in those inclined to tachyarrhythmia.
Hyoscine Butylbromide and Paracetamol Tablets (Hyocimax Plus Tablets) contain 4.32 mg of sodium per unit resulting in 25.92 mg sodium per maximum recommended daily dose. To be taken into consideration for patients on a controlled sodium diet.

Hyocimax Plus Tablets and Alcohol
Avoid the consumption of alcohol during the treatment of Hyoscine Butylbromide and Paracetamol Tablets (Hyocimax Plus Tablets) and consult your doctor for further information.
Hyoscine Butylbromide Tablets - Driving and Other Activities
Hyocimax Plus tablets may make you light-headed or impair your vision. Avoid activities such as driving, using machinery, or performing any activity that requires complete vigilance or perfect vision until you are sure about your safety.
Surgery and Regular Medical Tests
If you plan to have surgery or any dental procedure, inform your doctor, anesthetist, or dentist about your course of Hyoscine Butylbromide and Paracetamol tablets. In case of an emergency medical treatment, please inform the practitioner about your course of Hyocimax Plus tablets and the details of your last dose.

Side Effects of Hyoscine Butylbromide and Paracetamol Tablets (Hyocimax Plus Tablets)

The following side effects have been reported during the course of treatment with Hyocimax Plus tablets (Generic Hyoscine Butylbromide and Paracetamol tablets):
Blood and lymphatic system disorders: Pancytopenia, agranulocytosis, thrombocytopenia, leukopenia.
Immune system disorders, skin and subcutaneous tissue disorders: Skin reactions, sweating abnormal, pruritus, urticaria, nausea, erythema, blood pressure decreased including shock, anaphylactic shock, anaphylactic reactions, drug eruption, dyspnoea, hypersensitivity, angioedema, rash, exanthema.
Very rare cases of serious skin reactions (such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and acute generalized exanthematous pustulosis (AGEP) have been reported for paracetamol.
Cardiac disorders: Tachycardia.
Respiratory, thoracic and mediastinal disorders: Bronchospasm (especially in patients with a history of bronchial asthma or allergy).
Gastrointestinal disorders: Dry mouth.
Hepatobiliary disorders: Transaminases increased.
Renal and urinary disorders: Urinary retention.
Inform your doctor immediately if you experience any of these side effects. This is not a thorough list of all the potential side effects of Hyocimax tablets (Generic Hyoscine Butylbromide tablets). If you develop any other medical conditions during the course of treatment with Hyoscine Butylbromide tablets, please consult your doctor immediately.

Hyoscine Butylbromide and Paracetamol Tablets during Pregnancy and Breastfeeding

Hyoscine Butylbromide has been classified by the US FDA as Pregnancy Category C. Paracetamol has been classified by the US FDA as Pregnancy Category B.
There are no adequate data on use of Hyoscine Butylbromide and Paracetamol (Hyocimax Plus Plus) during pregnancy. Hyoscine Butylbromide tablets should not be administered Hyoscine Butylbromide Tablets, especially during the first trimester.
Due to the above mentioned reasons, pregnant women and breast feeding mothers who are undergoing treatment with Hyoscine Butylbromide and Paracetamol tablets should check with their doctor and understand its therapeutic benefits and associated risks before beginning the treatment with Hyoscine Butylbromide tablets.
During pregnancy, paracetamol should not be taken for prolonged periods, in high doses, or in combination with other medicinal products as the safety has not been confirmed in such cases. Therefore, Hyoscine-N-butylbromide + Paracetamol (Buscopan Plus) is not recommended during pregnancy.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.

Nursing Considerations

For Hyoscine Butylbromide and Paracetamol Tablets (Hyocimax Plus Tablets), safety during lactation has not yet been established. However, adverse effects on the newborn have not been reported.
It is still not known if Hyoscine Butylbromide is secreted into breastmilk. Nursing mothers should exercise caution if they are breastfeeding an infant during the course of Hyoscine Butylbromide tablets. Paracetamol enters breast milk, but is not likely to affect the infant when therapeutic doses are used.
Do not use this medication without telling your doctor if you are breast-feeding a baby.

Buy Hyoscine Butylbromide and Paracetamol Tablets Online at Only $0.49 per Pill

You can buy Hyoscine Butylbromide and Paracetamol tablets online from Everest Online Pharmacy at a cheap price. Hyocimax Plus tablets, manufactured by Acme Pharmaceuticals, marketed by German Remedies (Zydus Healthcare Limited, India) are available in pills of 10 mg+ 500 mg, which are priced at only $0.49 per unit if you place an order for 360 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith, it is without a warrant of any kind, expressed or implied.

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