Hydroxyzine Hydrochloride Tablets

Atarax Tablets (Hydroxyzine Hydrochloride Tablets) - Product Information

Atarax Tablets (Hydroxyzine Hydrochloride Tablets) is used to assist in the management of anxiety and tension caused by nervous and emotional conditions in adults. Atarax is useful in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses.
It is also used as a sedative when used as premedication such as preparation for dental procedures.
The effectiveness of hydroxyzine as an antianxiety agent for long term use, that is more than 4 months, has not been assessed by systematic clinical studies. The physician should reassess periodically the usefulness of the drug for the individual patient. Atarax tablets are manufactured by Dr. Reddy's Laboratories Limited, India in the strengths of 10 mg and 25 mg.
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Name of the Drug

Atarax Tablets.

Manufacturer of Atarax Tablets

Dr. Reddy's Laboratories Limited, India  
Website: www.drreddys.com

Active Pharmaceutical Ingredient

The active ingredient present in Atarax tablets is Hydroxyzine Hydrochloride. Each film-coated Atarax tablet contains 10 mg or 25 mg of Hydroxyzine Hydrochloride.

Uses of Atarax Tablets

Atarax Tablets (Hydroxyzine Hydrochloride Tablets) is indicated in adults for management of anxiety, Premedication, such as preparation for dental procedures and management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses.
Atarax is indicated in children for premedication, such as preparation for dental procedures, management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses. It is also indicated for control of nausea and vomiting, excluding nausea and vomiting of pregnancy.

Atarax Tablets - Dosage

Generic Hydroxyzine Hydrochloride tablets should be administered exactly as suggested by your doctor. Your doctor may recommend a dosage of Atarax tablets depending on your age, medical requirement, body weight, other medical conditions, and current medications.
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested: in adults, 50-100 mg four times a day; children under 6 years, 50 mg daily in divided doses and over 6 years, 50-100 mg daily in divided doses.
For use in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus: in adults, 25 mg three times a day or four times a day; children under 6 years, 50 mg daily in divided doses and over 6 years, 50-100 mg daily in divided doses.
As a sedative when used as a premedication and following general anesthesia: 50-100 mg in adults, and 0.6 mg/kg in children.
Atarax tablets work effectively if the amount of Hydroxyzine Hydrochloride is maintained at a constant level in the body. You should be systematic about the daily schedule for the medication such that you take Tryptomer tablets at about the same time every day, to get the maximum benefit of the medication. Continue taking Atarax tablets without missing any doses for the recommended treatment period and do not stop the treatment suddenly even if you feel better.

Please consult your doctor for exact dosing instructions. Atarax tablets (Generic Hydroxyzine Hydrochloride tablets) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Missed Dose

If you forget to take your regular tablet dose on time, take it whenever you remember.
If you remember the next day, skip the missed dose and take your scheduled dose. Do not take a double dose to compensate the missed dose.

Hydroxyzine Hydrochloride Tablets - Mechanism of Action

Hydroxyzine is not a cortical depressant, but its action may be due to a suppression of activity in certain key regions of the subcortical area of the central nervous system.
Primary skeletal muscle relaxation has been demonstrated experimentally. Bronchodilator activity, and antihistaminic and analgesic effects have been demonstrated experimentally and confirmed clinically.

Storage Instructions for Atarax Tablets (Hydroxyzine Hydrochloride Tablets)

Store Atarax tablets at controlled room temperature (20°C to 25°C),protected from heat, moisture, and sunlight. Excursions are permitted from 15°C to 30°C.
Retain the original packing of the medication and do not consume past its expiration date printed on the blister pack. Keep the pack of Hydroxyzine Hydrochloride tablets away from the reach of children and pets. Do not dispose Atarax tablets along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.

Contraindications

Atarax tablets are contraindicated in patients with a hypersensitivity to Hydroxyzine Hydrochloride or any inactive ingredient present in tablets. Atarax tablets are also contraindicated in patients with:
history of QT prolongation and/or torsade de pointes, including congenital long QT syndromes; history of cardiac arrhythmias; significant electrolyte imbalance (hypokalaemia, hypomagnesium); significant bradycardia; family history of sudden cardiac death; concomitant use of other QT/QTc-prolonging drugs, or of CYP3A4/5 inhibitors.
asthmatics who have previously experienced a serious anti-histamine induced adverse bronchopulmonary effect.
porphyria
early (first trimester) pregnancy

Overdose

The most common manifestation of Hydroxyzine overdosage is hypersedation. Other reported signs and symptoms were convulsions, stupor, nausea and vomiting.
As in the management of overdosage with any drug, it should be borne in mind that multiple agents may have been taken.
If vomiting has not occurred spontaneously, it should be induced. Immediate gastric lavage is also recommended. General supportive care, including frequent monitoring of the vital signs and close observation of the patient, is indicated.

Warnings and Precautions

General
Because of its potential antimuscarinic actions, Atarax Tablets (Hydroxyzine Hydrochloride Tablets) should be used with caution in patients suffering from angle closure glaucoma, urinary retention, prostatic hyperplasia, or pyloroduodenal obstruction
Concomitant Use with CNS depressants:
The potentiating action of Hydroxyzine Hydrochloride must be considered when the drug is used in conjunction with CNS depressants such as narcotics, non-narcotic analgesics, hypnotics, sedatives, psychotherapeutic agents, barbiturates or alcohol. Therefore, when CNS depressants are administered concomitantly with Atarax, their dosage should be reduced.
Cardiovascular:
Caution is required in patients with cardiovascular disease and hypertension. Hydroxyzine has been associated with QT/QTc interval prolongation. Rare events of torsade de pointes, cardiac arrest, and sudden death have been reported with hydroxyzine during post market use.
Driving and Operating Machinery:
Since drowsiness may occur with use of this drug, patients should be cauti oned against driving a car or operating dangerous machinery while taking Hydroxyzine.
Endocrine and Metabolism:
Caution is required in patients with hyperthyroidism.
Gastrointestinal:
Caution is required in patients with decreased GI motility and stenosing peptic ulcer. Hepatic/Biliary/Pancreatic: Use in patients with severe liver impairment should be avoided
Neurologic:
Caution is required in patients with seizure disorders, including epilepsy and in patients with myasthenia gravis and dementia.
Ophthalmologic:
Caution is required in patients with increased intraocular pressure.

Side Effects of Atarax Tablets (Hydroxyzine Hydrochloride Tablets

Skin and Appendages: Oral Hydroxyzine Hydrochloride is associated with fixed drug eruptions in postmarketing reports Side effects reported with the administration of hydroxyzine hydrochloride are usually mild and transitory in nature.
Anticholinergic: Dry mouth.
Central Nervous System: Drowsiness is usually transitory and may disappear in a few days of continued therapy or upon reduction of dose.
Involuntary motor activity including rare instances of tremor and convulsions have been reported, usually with doses considerably higher than those recommended.

Hydroxyzine Hydrochloride During Pregnancy and Breastfeeding

Hydroxyzine Hydrochloride has been classified by the US FDA as Pregnancy Category C.
Hydroxyzine hydrochloride, when administered to the pregnant mouse, rat, and rabbit, induced fetal abnormalities in the rat and mouse at doses substantially above the human therapeutic range.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.
It is not known whether this drug is excreted in human milk. Since many drugs are so excreted, Hydroxyzine should not be given to nursing mothers.
Do not use this medication without telling your doctor if you are breast-feeding a baby.

Buy Generic Hydroxyzine Hydrochloride Pills (Atarax 10 mg and 25 mg Tablets) Online From Only $0.20 per Pill

You can buy Generic Hydroxyzine Hydrochloride Tablets online from Everest Online Pharmacy at a cheap price. Atarax Tablets 10 mg and 25 mg pills, manufactured by Dr. Reddy's Laboratories Limited, India, are supplied in a blister strip of 15 tablets. The 10 mg tablets cost only $0.20 per unit when you place an order for 300 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith. It is without a warrant of any kind, expressed or implied.

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