Generic Gabapentin

Generic Gabapentin (Gabasign Capsules and Tablets) - Product Information

Gabapentin is used to help control partial seizures (convulsions) in the treatment of epilepsy. This medicine cannot cure epilepsy and will only work to control seizures for as long as you continue to take it.
Gabapentin is also used to manage a condition called postherpetic neuralgia, which is pain that occurs after shingles.
Gabapentin works in the brain to prevent seizures and relieve pain for certain conditions in the nervous system. It is not used for routine pain caused by minor injuries or arthritis.

We also have in stock Tegrital CR Tablets (Generic Carbamazepine 200 mg, 300 mg and 400 mg) which are anticonvulsants and are prescribed for the treatment of epileptic seizures, bipolar disorders, trigeminal neuralgia and diabetic neuropathy.

Name of the Drug

Gabasign capsules and tablets.

Manufacturer of Gabasign Capsules and Tablets

HAB Pharmaceuticals & Research Limited, India (Signature)  
Website: habpharma.com

Active Pharmaceutical Ingredient

The active ingredient present in Gabasign Capsules and tablets is Gabapentin. Each capsule or tablet contains 300 mg, 600 mg or 800 mg of the active ingredient Gabapentin.

Uses of Gabasign Capsules and Tablets

Gabapentin (Gabasign Capsules and Tablets) is prescribed to prevent and control partial seizures, relieve postherpetic neuralgia after shingles and moderate-to-severe restless legs syndrome. Gabapentin is used to:
Prevent and control partial seizures. Gabapentin can be used in adults and children age 3 and older who have partial seizures.
Relieve nerve pain following shingles in adults. Shingles is a painful rash that develops many years after you've had chickenpox. The virus that causes chickenpox stays dormant in a portion of your spinal nerve root called the dorsal root ganglion. For whatever reason, this otherwise dormant virus gets reactivated — usually by stress — causing a shingles rash. Nerve pain following a case of shingles is called postherpetic neuralgia (PHN).
Treat moderate-too-severe primary restless legs syndrome.

Gabapentin (Gabasign Capsules and Tablets) - Dosage

Generic Gabapentin tablets should be administered exactly as suggested by your doctor. Your doctor may recommend a dosage of Gabasign capsules depending on your age, medical requirement, body weight, other medical conditions, and current medications.
Postherpetic Neuralgia:

• Dose can be titrated up as needed to a dose of 1800 mg/day
• Day 1: Single 300 mg dose
• Day 2: 600 mg/day (i.e., 300 mg two times a day)
• Day 3: 900 mg/day (i.e., 300 mg three times a day)

Epilepsy with Partial Onset Seizures:

• Patients 12 years of age and older: starting dose is 300 mg three times daily; may be titrated up to 600 mg three times daily
• Patients 3 to 11 years of age: starting dose range is 10 to 15 mg/kg/day, given in three divided doses;
• Patients 3 to 4 years of age:Recommended dose in patients 3 to 4 years of age is 40 mg/kg/day, given in three divided doses;
• Patients 5 to 11 years of age:Recommended dose in patients 5 to 11 years of age is 25 to 35 mg/kg/day, given in three divided doses
• The recommended dose is reached by upward titration over a period of approximately 3 days

Dose should be adjusted in patients with reduced renal function
Gabasign capsules and tablets work effectively if the amount of Gabapentin is maintained at a constant level in the body. You should be systematic about the daily schedule for the medication such that you take Gabasign capsules or tablets at about the same time every day, to get the maximum benefit of the medication. Continue taking Gabasign capsules or tablets without missing any doses for the recommended treatment period and do not stop the treatment suddenly even if you feel better.

Please consult your doctor for exact dosing instructions. Gabasign Capsules and Tablets(Generic Gabapentin) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Missed Dose

If you forget to take your regular tablet dose on time, take it whenever you remember.
If you remember the next day, skip the missed dose and take your scheduled dose. Do not take a double dose to compensate the missed dose.

Mechanism of Action –

Gabapentin works by showing a high affinity for binding sites throughout the brain corresponding to the presence of the voltage-gated calcium channels, especially alpha-2-delta-1, which seems to inhibit the release of excitatory neurotransmitters in the presynaptic area that participate in epileptogenesis.
In summary, Gabapentin's main action is to modulate calcium channel function by binding to alpha-2-delta subunits, leading to a decrease in excitatory neurotransmitter release. This contributes to its effectiveness in treating seizures and neuropathic pain.

Storage Instructions for Gabasign Capsules and Tablets

Store Gabasign Capsules and tablets at controlled room temperature (20°C to 25°C),protected from heat, moisture, and sunlight. Excursions are permitted from 15°C to 30°C.
Retain the original packing of the medication and do not consume past its expiration date printed on the blister pack. Keep the pack of Generic Gabapentin away from the reach of children and pets. Do not dispose Gabapentin capsules or tablets along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.

Contraindications

Gabasign capsules and tablets are contraindicated in patients with a hypersensitivity to Gabapentin or any inactive ingredient present in Gabasign capsules and tablets.

Overdose

Signs of acute toxicity in animals included ataxia, labored breathing, ptosis, sedation, hypoactivity, or excitation.
Acute oral overdoses of Gabapentin (Gabasign Capsules and Tablets) up to 49 grams have been reported. In these cases, double vision, slurred speech, drowsiness, lethargy, and diarrhea were observed. All patients recovered with supportive care. Coma, resolving with dialysis, has been reported in patients with chronic renal failure who were treated with Gabapentin.

Warnings and Precautions

Drug Reaction with Eosinophilia and Systemic Symptoms (Multiorgan hypersensitivity):
Discontinue if alternative etiology is not established.
Anaphylaxis and Angioedema:
Discontinue and evaluate patient immediately
Driving Impairment; Somnolence/Sedation and Dizziness:
Warn patients not to drive until they have gained sufficient experience to assess whether their ability to drive or operate heavy machinery will be impaired
Increased Seizure Frequency:
Increased seizure frequency may occur in patients with seizure disorders if Gabasign capsules or tablets are abruptly discontinued
Suicidal Behavior and Ideation:
Monitor for suicidal thoughts/behavior
Neuropsychiatric Adverse Reactions in Children 3 to 12 Years of Age:
Monitor for such events.

Side Effects of Gabapentin (Gabasign Capsules and Tablets)

Most common side effects with an incidence rate of 8% or more and at least twice that for placebo) were:

• Postherpetic neuralgia: Dizziness, somnolence, and peripheral edema
• Epilepsy in patients more than 12 years of age: Somnolence, dizziness, ataxia, fatigue, and nystagmus
• Epilepsy in patients 3 to 12 years of age: Viral infection, fever, nausea and/or vomiting, somnolence, and hostility

Gabapentin (Gabasign Capsules and Tablets) During Pregnancy and Breastfeeding

Gabapentin (Gabasign capsules and tablets) has been classified by the US FDA as Pregnancy Category C.
There are no adequate data on the developmental risks associated with the use of Gabapentin (Gabasign Capsules and Tablets) in pregnant women. In nonclinical studies in mice, rats, and rabbits, Gabapentin was developmentally toxic (increased fetal skeletal and visceral abnormalities, and increased embryofetal mortality) when administered to pregnant animals at doses similar to or lower than those used clinically.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.
Gabapentin is secreted in human milk following oral administration. The effects on the breastfed infant and on milk production are unknown.
The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for Gabasign and any potential adverse effects on the breastfed infant from Gabasign or from the underlying maternal condition. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Buy Generic Gabapentin 300 mg , 600 mg and 800 mg Pills Online From Only $0.30 per Pill

You can buy Generic Gabapentin online from Everest Online Pharmacy at a cheap price. Gabasign 300 mg Capsules and Gabasign 600 mg and 800 mg tablets, manufactured by HAB Pharmaceuticals & Research Limited (Signature), India, are supplied in a blister strip of 10 capsules or tablets. The cost of Gabapentin generic (Gabasign 300 mg capsules) is only $0.30 per unit when you place an order for 400 capsules.

Disclaimer

The above information is provided to the best of our knowledge and in good faith. It is without a warrant of any kind, expressed or implied.

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