Gabantin Capsules

Gabapentin Capsules (Gabantin Capsules) - Product Information

Gabapentin Capsules (Gabantin Capsules) are used for the adjunctive therapy in the treatment of partial onset seizures (convulsions), with and without secondary generalization, in adults and pediatric patients 3 years and older with epilepsy. This medicine cannot cure epilepsy and will only work to control seizures for as long as you continue to take it.
They are also used for management of postherpeticneuralgia (in adults), which is pain that occurs after shingles.
We also have in stock Tegrital CR Tablets (Generic Carbamazepine 200 mg, 300 mg and 400 mg) which are anticonvulsants and are prescribed for the treatment of epileptic seizures, bipolar disorders, trigeminal neuralgia and diabetic neuropathy.

Name of the Drug

Gabantin Capsules.

Manufacturer of Tablets

Sun Pharmaceutical Industries Limited, India  
Website: sunpharma.com

Active Pharmaceutical Ingredient

The active ingredient present in Gabantin capsules is Gabapentin. Each Gabantin capsule contains 100 mg, 300 mg or 400 mg of Gabapentin.

Uses of Gabantin Capsules (Generic Gabapentin)

Gabapentin (Gabantin Capsules) is prescribed to prevent and control partial seizures, relieve postherpetic neuralgia after shingles and moderate-to-severe restless legs syndrome.
Gabantin Capsules (Generic Gabapentin) is used to treat pain you may have from shingles (postherpetic nerve pain). Shingles is a painful rash that develops many years after you've had chickenpox. The virus that causes chickenpox stays dormant in a portion of your spinal nerve root called the dorsal root ganglion. For whatever reason, this otherwise dormant virus gets reactivated - usually by stress - causing a shingles rash. Nerve pain following a case of shingles is called postherpetic neuralgia (PHN). It is not used for routine pain caused by minor injuries or arthritis.
It is also used with other seizure medicines for partial onset seizures in patients 3 years and older. Gabapentin works in the brain to prevent seizures and relieve pain for certain conditions in the nervous system.
Treat moderate-too-severe primary restless legs syndrome.

Gabantin Capsules (Generic Gabapentin) - Dosage

Generic Gabapentin capsules should be administered exactly as suggested by your doctor. Your doctor may recommend a dosage of Gabantin Capsules depending on your age, medical requirement, body weight, other medical conditions, and current medications.
Postherpetic Neuralgia
Dose can be titrated up as needed to a dose of 1800 mg/day
Day 1: Single 300 mg dose
Day 2: 600 mg/day (i.e., 300 mg two times a day)
Day 3: 900 mg/day (i.e., 300 mg three times a day)

Epilepsy with Partial Onset Seizures
Patients 12 years of age and older: starting dose is 300 mg three times daily; may be titrated up to 600 mg three times daily
Patients 3 to 11 years of age: starting dose range is 10 to 15 mg/kg/day, given in three divided doses; recommended dose in patients 3 to 4 years of age is 40 mg/kg/day, given in three divided doses; the recommended dose in patients 5 to 11 years of age is 25 to 35 mg/kg/day, given in three divided doses. The recommended dose is reached by upward titration over a period of approximately 3 days
Dose should be adjusted in patients with reduced renal function

Gabantin Capsules work effectively if the amount of Gabapentin is maintained at a constant level in the body. You should be systematic about the daily schedule for the medication such that you take tablets at about the same time every day, to get the maximum benefit of the medication. Continue taking Gabantin Capsules without missing any doses for the recommended treatment period and do not stop the treatment suddenly even if you feel better.

Please consult your doctor for exact dosing instructions. Gabantin Capsules (Generic Gabapentin capsules) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Missed Dose

If you forget to take your regular Gabantin Capsules dose on time, take it whenever you remember.
If you remember the next day, skip the missed dose and take your scheduled dose. Do not take a double dose to compensate the missed dose.

Gabantin Capsules Mechanism of Action

Gabapentin works by showing a high affinity for binding sites throughout the brain corresponding to the presence of the voltage-gated calcium channels, especially alpha-2-delta-1, which seems to inhibit the release of excitatory neurotransmitters in the presynaptic area that participate in epileptogenesis.
In summary, Gabapentin's main action is to modulate calcium channel function by binding to alpha-2-delta subunits, leading to a decrease in excitatory neurotransmitter release. This contributes to its effectiveness in treating seizures and neuropathic pain.

Storage Instructions for Gabantin Capsules

Store Gabantin Capsules at controlled room temperature (20°C to 25°C),protected from heat, moisture, and sunlight. Excursions are permitted from 15°C to 30°C.
Retain the original packing of the medication and do not consume past its expiration date printed on the blister pack. Keep the pack of Generic Gabapentin away from the reach of children and pets. Do not dispose Gabapentin capsules or tablets along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.

Contraindications

Gabantin capsules are contraindicated in patients with a hypersensitivity to Gabapentin or any inactive ingredient present in Gabantin capsules.

Overdose

Signs of acute toxicity in animals included ataxia, labored breathing, ptosis, sedation, hypoactivity, or excitation.
Acute oral overdoses of Gabapentin (Gabantin Capsules) up to 49 grams have been reported. In these cases, double vision, slurred speech, drowsiness, lethargy, and diarrhea were observed. All patients recovered with supportive care. Coma, resolving with dialysis, has been reported in patients with chronic renal failure who were treated with Gabapentin.

Warnings and Precautions

Drug Reaction with Eosinophilia and Systemic Symptoms (Multiorgan hypersensitivity):
Discontinue if alternative etiology is not established.
Anaphylaxis and Angioedema:
Discontinue and evaluate patient immediately
Driving Impairment; Somnolence/Sedation and Dizziness:
Warn patients not to drive until they have gained sufficient experience to assess whether their ability to drive or operate heavy machinery will be impaired
Increased Seizure Frequency:
Increased seizure frequency may occur in patients with seizure disorders if Gabantin capsules or tablets are abruptly discontinued
Suicidal Behavior and Ideation:
Monitor for suicidal thoughts/behavior
Neuropsychiatric Adverse Reactions in Children 3 to 12 Years of Age:
Monitor for such events.

Side Effects of Gabapentin (Gabantin Capsules and Tablets)

Most common side effects with an incidence rate of 8% or more and at least twice that for placebo) were:

• Postherpetic neuralgia: Dizziness, somnolence, and peripheral edema
• Epilepsy in patients more than 12 years of age: Somnolence, dizziness, ataxia, fatigue, and nystagmus
• Epilepsy in patients 3 to 12 years of age: Viral infection, fever, nausea and/or vomiting, somnolence, and hostility

Side Effects of Gabantin capsules

Most common Gabantin capsules side effects with an incidence rate of 8% or more and at least twice that for placebo) were:
Postherpetic neuralgia: Dizziness, somnolence, and peripheral edema
Epilepsy in patients >12 years of age: Somnolence, dizziness, ataxia, fatigue, and nystagmus
Epilepsy in patients 3 to 12 years of age: Viral infection, fever, nausea and/or vomiting, somnolence, and hostility

Gabapentin Capsules During Pregnancy

Gabapentin Capsules have been classified by the US FDA as Pregnancy Category C.
There are no adequate data on the developmental risks associated with the use of Gabapentin (Gabantin Capsules and Tablets) in pregnant women. In nonclinical studies in mice, rats, and rabbits, Gabapentin was developmentally toxic (increased fetal skeletal and visceral abnormalities, and increased embryofetal mortality) when administered to pregnant animals at doses similar to or lower than those used clinically.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.
Gabapentin is secreted in human milk following oral administration. The effects on the breastfed infant and on milk production are unknown.
The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for Gabantin and any potential adverse effects on the breastfed infant from Gabantin or from the underlying maternal condition. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Buy Gabapentin 100 mg, 300 mg and 400 mg Pills Online From Only $0.33 per Pill

You can buy Generic Gabapentin online from Everest Online Pharmacy at a cheap price. Gabantin 100 mg, 300 mg and 400 mg pills, manufactured by Sun Pharmaceutical Industries Limited, India are supplied in a blister strip of 10 capsules. The cost of Gabapentin generic (Gabantin 100 mg capsules) is only $0.33 per unit when you place an order for 360 capsules.

Disclaimer

The above information is provided to the best of our knowledge and in good faith. It is without a warrant of any kind, expressed or implied.

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