Cyproheptadine Hydrochloride Tablets

Ciplactin Tablets (Generic Cyproheptadine Hydrochloride Tablets) - Product Information

Ciplactin (Cyproheptadine Hydrochloride Tablets) prevents and treats allergy symptoms, such as red, itchy eyes, sneezing, a runny or stuffy nose, or hives. It works by blocking histamine, a substance released by the body during an allergic reaction.
Ciplactin can promote weight gain by increasing appetite and food intake. It's been used to help individuals with poor appetite or those who have difficulty gaining weight, including children and adults.
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Name of the Drug

Ciplactin Tablets.

Manufacturer of Ciplactin Tablets

Cipla Limited, India  
Website: www.cipla.com

Active Pharmaceutical Ingredient

The active ingredient present in Ciplactin Tablets is Cyproheptadine Hydrochloride. Each Ciplactin tablet contains 4 mg of Cyproheptadine Hydrochloride (anhydrous) IP.

Uses of Ciplactin Tablets (Generic Cyproheptadine Hydrochloride Tablets)

Ciplactin tablets are used for the treatment of Perennial and seasonal allergic rhinitis, Vasomotor rhinitis, Allergic conjunctivitis due to inhalant allergens and foods, Mild, uncomplicated allergic skin manifestations of urticaria and angio-oedema, Amelioration of allergic reactions to blood or plasma, Cold urticaria and Dermatographism.
Generic Cyproheptadine Hydrochloride Tablets are also used as therapy for anaphylactic reactions adjunctive to epinephrine and other standard measures after the acute manifestations have been controlled.
Cyproheptadine, an antihistamine with serotonin-blocking properties, can promote weight gain by increasing appetite and food intake. It's been used to help individuals with poor appetite or those who have difficulty gaining weight, including children and adults. While effective, it's important to consult with a healthcare professional before using cyproheptadine for weight gain, as it can have side effects and is not suitable for everyone. Clinical trials have showed patients gaining 3 kg as compared to 1.3 kg for the placebo group at the conclusion of the 12 week trial.

Ciplactin Tablets - Dosage

Generic Cyproheptadine Hydrochloride tablets should be administered exactly as suggested by your doctor. Dosage should be individualized according to the needs and the response of the patient. Your doctor will recommend a dosage of Ciplactin tablets depending on your age, medical requirement, body weight, other medical conditions, and current medications.
Adult Dosage:
The total daily dose for adults should not exceed 0.5 mg/kg/day. The therapeutic range is 4 to 20 mg a day, with the majority of patients requiring 12 to 16 mg a day. An occasional patient may require as much as 32 mg a day for adequate relief. It is suggested that dosage be initiated with 4 mg (one tablet) three times a day and adjusted according to the size and response of the patient.
Ciplactin tablets work effectively if the amount of Cyproheptadine Hydrochloride is maintained at a constant level in the body. You should be systematic about the daily schedule for the medication such that you take Ciplactin tablets at about the same time every day, to get the maximum benefit of the medication. Continue taking tablets without missing any doses for the recommended treatment period and do not stop the treatment suddenly even if you feel better.

Please consult your doctor for exact dosing instructions. Ciplactin tablets (Generic Cyproheptadine Hydrochloride tablets) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Missed Dose

If you forget to take your regular Ciplactin tablet dose on time, take it whenever you remember.
If you remember the next day, skip the missed dose and take your scheduled dose. Do not take a double dose to compensate the missed dose.

Cyproheptadine Hydrochloride Mechanism of Action

Cyproheptadine is an antihistamine. It works by blocking the effect of a substance in your body called histamine.
Cyproheptadine appears to exert its antihistamine and antiserotonin effects by competing with free histamine and serotonin for binding at their respective receptors. Antagonism of serotonin on the appetite center of the hypothalamus may account for Cyproheptadine's ability to stimulate the appetite.

Storage Instructions for Ciplactin Tablets (Cyproheptadine Hydrochloride Tablets)

Store Ciplactin tablets at controlled room temperature (20°C to 25°C),protected from heat, moisture, and sunlight. Excursions are permitted from 15°C to 30°C.
Retain the original packing of the medication and do not consume past its expiration date printed on the blister pack. Keep the pack of Cyproheptadine Hydrochloride tablets away from the reach of children and pets. Do not dispose Ciplactin tablets along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.

Contraindications

Ciplactin tablets are contraindicated in patients with a hypersensitivity to Cyproheptadine Hydrochloride or any inactive ingredient present in tablets. Ciplactin tablets are contraindicated in the following cases:

• patients undergoing therapy for an acute asthmatic attack;
• newborn or premature infants; use in infants has been associated with apnoea, cyanosis and respiratory difficulty
• breast-feeding mothers;
• concurrent use with monoamine oxidase inhibitors;
• glaucoma;
• patients with pyloroduodenal obstruction, stenosing peptic ulcer, symptomatic prostatic hypertrophy, predisposition to urinary retention or bladder neck obstruction;
• elderly, debilitated patients

Overdose

Antihistamine overdosage reactions may vary from CNS depression to stimulation especially in pediatric patients. Also, atropine-like signs and symptoms (dry-mouth; fixed, dilated pupils; flushing etc.) as well as gastrointestinal symptoms may occur.
If vomiting has not occurred spontaneously, the patient should be induced to vomit with syrup of ipecac.
If the patient is unable to vomit, perform gastric lavage followed by activated charcoal. Isotonic or half isotonic saline is the lavage of choice. Precautions against aspiration must be taken especially in infants and children.
When life-threatening CNS signs and symptoms are present, intravenous physostigmine salicylate may be considered.
Saline cathartics, as milk of magnesia, draw water into the bowel by osmosis and, therefore, are valuable for their action in rapid dilution of bowel contents.
Stimulants should not be used.Vasopressors may be used to treat hypotension.

Warnings and Precautions

Lower Respiratory Tract Symptoms:
Antihistamines should not be used to treat lower respiratory tract symptoms, including those of acute asthma.
Children under 2 years old
The safety and efficacy of 'Cyproheptadine Hydrochloride 4 mg Tablets' is not established in children under 2 years old.
Overdosage
Overdosage of antihistamines, particularly in infants and children, may produce hallucinations, central nervous system depression, convulsions, respiratory and cardiac arrest, and death.
mental alertness
Antihistamines may diminish mental alertness; conversely, particularly in the young child, they may occasionally produce excitation.
Driving A Car Or Operating Machinery:
Patients should be warned against engaging in activities requiring motor co-ordination and mental alertness, such as driving a car or operating machinery.
Blood Dyscrasias
Rarely, prolonged therapy with antihistamines may cause blood dyscrasias. Because 'Cyproheptadine Hydrochloride 4 mg Tablets' has an atropine-like action, it should be used cautiously in patients with a history of bronchial asthma, increased intra-ocular pressure, hyperthyroidism, cardiovascular disease, or hypertension.
Excipients
Patients with rare hereditary problems of galactose intolerance, the Lapp lastase deficiency or glucose-galactose malabsorption should not take this medicine.

Side Effects of Ciplactin Tablets (Cyproheptadine Hydrochloride Tablets)

The Cyproheptadine Hydrochloride (Ciplactin tablets) side effects that appear frequently are drowsiness and somnolence. Many patients who initially complain of drowsiness may no longer do so after the first three to four days of continuous administration.Side effects reported with antihistamines are:

• Central Nervous System: Sedation and sleepiness (often transient), dizziness, disturbed coordination, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, paraesthesias, neuritis, convulsions, euphoria, hallucinations, hysteria, faintness.
• Integumentary: Allergic manifestation of rash and oedema, excessive perspiration, urticaria, photosensitivity.
• Special Senses: Acute labyrinthitis, blurred vision, diplopia, vertigo, tinnitus.
• Cardiovascular: Hypotension, palpitation, tachycardia, extrasystoles, anaphylactic shock.
• Hematologic: Haemolytic anaemia, leucopenia, agranulocytosis, thrombocytopenia.
• Digestive System: Cholestasis, hepatic failure, hepatitis, hepatic function abnormality, dryness of mouth, epigastric distress, anorexia, nausea, vomiting, diarrhoea, constipation, jaundice.
• Genitourinary: Urinary frequency, difficult urination, urinary retention, early menses.
• Respiratory: Dryness of nose and throat, thickening of bronchial secretions, tightness of chest and wheezing, nasal stuffiness.
• Miscellaneous: Fatigue, chills, headache, increased appetite/weight gain.

Cyproheptadine Hydrochloride (Ciplactin Tablets) During Pregnancy

Cyproheptadine Hydrochloride has been classified by the US FDA as Pregnancy Category B.
Reproduction studies have been performed in rabbits, mice and rats at oral or subcutaneous doses up to 32 times the maximum recommended human oral dose and have revealed no evidence of impaired fertility or harm to the foetus due to Cyproheptadine Hydrochloride. Cyproheptadine Hydrochloride has been shown to be foetotoxic in rats when given by intraperitoneal injection in doses four times the maximum recommended human oral dose.
Two studies in pregnant women, however, have not shown that Cyproheptadine Hydrochloride increases the risk of abnormalities when administered during the first, second and third trimesters of pregnancy.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.

Ciplactin Tablets Nursing Considerations

It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, and because of the potential for serious adverse reactions in lactating infants from Cyproheptadine Hydrochloride, a decision should be made whether to discontinue lactation or to discontinue the drug, taking into account the importance of the drug to the mother
Do not use this medication without telling your doctor if you are breast-feeding a baby.

Buy Generic Cyproheptadine Hydrochloride 4 mg Pills Online From Only $0.16 per Pill

You can buy Generic Cyproheptadine Hydrochloride online from Everest Online Pharmacy at a cheap price. Ciplactin 4 mg pills, manufactured by Cipla Limited, India are supplied in a blister strip of 10 tablets. The 4 mg tablets cost only $0.16 per unit when you place an order for 750 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith. It is without a warrant of any kind, expressed or implied.

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