Tiotropium Bromide Inhalation Powder

Tiova Rotacaps (Tiotropium 18 mcg Inhalation Powder) - Product Information

Tiova Rotacaps, also known as Tiotropium Bromide Inhalation Powder, are used by patients suffering from different bronchospasm difficulties such as bronchitis, emphysema, or COPD (chronic obstructive pulmonary disease).
Tiova Rotacaps belongs to the class of drugs called anticholinergics. Tiotropium Bromide Inhalation Powder is prescribed as oral inhalation therapy for the effective prevention of airways narrowing in the lungs which results in typical symptoms such as shortness of breath, chronic cough with sputum production, tightness of the chest and wheezing. Tiova Rotacaps are used for the long-term therapy and also prevention of breathing ailments such as bronchitis and emphysema.
The contents of Tiova Rotacaps should only be administered for inhalation and not for oral purposes. When the content of Tiova Rotacaps are sprayed from the inhaler, it moves directly into the airways.
In our online pharmacy, Tiotropium Bromide Inhalation Powder is available in the strength of 18 mcg of Beclomethasone Dipropionate.
We also have in stock Foracort Rotacaps (Budesonide And Formoterol Dry Powder Inhaler) which is used to treat patients diagnosed with different bronchospasm ailments such as bronchitis, emphysema, or COPD (chronic obstructive pulmonary disease).

Name of the Drug

Tiova Rotacaps. Tiova Rotacaps are also known as Tiotropium Bromide Inhalation Powder.

Manufacturer of Tiotropium Bromide Inhalation Powder

Tiotropium Bromide Inhalation Powder, available in our online pharmacy are manufactured by Cipla Limited, India.  
Website: www.cipla.com

Active Pharmaceutical Ingredient

The active ingredient present in Tiova Rotacaps is Tiotropium Bromide. Each Tiova Rotacap contains 18 mcg of Tiotropium. The inactive ingredients in Tiova Rotacaps are lactose monohydrate and hard gelatine.

Tiotropium Bromide Inhalation Powder Indications-What is Tiova Rotacaps Used For?

Tiova Rotacaps, manufactured by Cipla Pvt. Ltd. in the strength of 18 mcg, are used for the treatment and prevention of COPD (chronic obstructive pulmonary disease) and related breathing ailments such as bronchitis and emphysema.
Tiova Rotacaps (Tiotropium bromide inhalation powder) contains a dry powder formulation of Tiotropium Bromide in the dosage form of a capsule. Tiova Rotacaps can only be administered for oral inhalation through the Tiova HandiHaler inhalation device. Tiova Rotacaps is used by patients suffering from typical symptoms of chronic obstructive pulmonary disease (COPD), bronchitis and emphysema such as shortness of breath, chronic cough with sputum production, tightness of the chest and wheezing. Tiova Rotacaps is an anticholinergic agent, which exerts its therapeutic effect by expanding the airways to permit relaxed breathing.

Tiotropium Bromide Inhalation Powder Dosage - How to Use Tiova Rotacaps?

You should use Tiova Rotacaps exactly as suggested by your doctor. The recommended dosage of Tiova Rotacaps is one Rotacap, administered once daily. The contents of Tiova Rotacaps should not be swallowed and should strictly only be inhaled using the special Cipla Rotahaler.
While taking out one Tiova Rotacap from the pack, tear out the foil and tap the pack to let the capsule out without touching it with your hands. Avoid cutting the foil or using any sharp object to take out the capsule. Do not take out a Tiova Rotacap from its intact pack until you are ready to use it. If other capsules in the pack come in contact with the environment when you are removing a capsule for use, it must be thrown away. Do not preserve the capsule for future usage.
After removing Tiova Rotacap from the pack, it must instantly be placed in a special inhaler device. The device will crush the capsule so that the content inside the capsule can be easily inhaled into the lungs through the mouthpiece. While using the inhalation device, make sure that you exhale gently and deeply. Avoid breathing into the mouthpiece of the inhaler while administering the Tiova Rotacap. Place the mouthpiece of the inhaler between your lips and try to maintain your tongue in a flat and steady position, while keeping your head straight. When you take a slow and deep breath, you should hear or feel the capsule pulsate inside the inhaler. You can hold your breath until you start to feel breathless and then slowly breathe out while keeping lips pressed together. To ensure the usage of the whole medication from the capsule, inhale from the mouthpiece again for a second time following the same steps as before. Consult your doctor or pharmacist if you are uncertain about how to use the special inhaler device or inhale the Tiova Rotacap.
You should clean the inhaler device at least once every month by referring to the instructions in the patient leaflet. Each inhaler device may last for a period of one year, after which it should be replaced. Use Tiova Rotacaps at the same time every day, so that you will remember to use it regularly. Tiova HandiHaler should be used on a regular basis without missing any doses to get the maximum therapeutic benefit from it.
Please consult your doctor for exact dosing instructions. Tiova Rotacaps (Generic Tiotropium Bromide Inhalation Powder) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Missed Dose

If you miss your regular dose of Tiova Rotacaps, take it as soon as you remember. You can continue your regular schedule the next day. If you remember the missed Tiova Rotacaps the next day, take your regular dose and skip the missed dose.
Do not take a double dose to compensate the missed dose of Tiotropium Bromide Inhalation Powder.

Tiotropium Bromide Inhalation Powder Mechanism of Action – How Does Tiova Rotacaps Work?

Tiova Rotacaps contain Tiotropium Bromide as the active ingredient which acts as a bronchodilator. Tiotropium is a long-acting anticholinergic that regulates particular muscarinic receptors present in the bronchioles of the lung to obstruct the neurotransmitter called acetylcholine from attaching to the muscarinic receptors, thus inhibiting the spasm of the airway wall. When acetylcholine action in the airways is stopped, the smooth muscles located in the airway walls relax which expands the airways and intensifies air flow into the lungs to ease bronchospasm (narrowing of the airways). When Tiotropium is administrated through an inhalator, it directly reaches the lungs and does not pass into the blood circulation. Regular long-term use of Tiotropium Bromide Inhalation Powder alleviate characteristic symptoms of COPD such as shortness of breath, chronic cough with sputum production, tightness of the chest and wheezing.

Storage Instructions for Tiova Rotacaps

Store Tiova Rotacaps at controlled room temperature (20°C to 25°C),protected from heat, moisture, and sunlight. Excursions are permitted from 15°C to 30°C.
Retain the original packing of the medication and do not consume Tiova Rotacaps (Tiotropium Bromide Inhalation Powder) beyond its expiration date printed on the canister. Keep the pack of Tiotropium Bromide Inhalation Powder away from the reach of children and pets. Do not discard Tiotropium Bromide Inhalation Powder along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.

Contraindications

Tiova Rotacaps are contraindicated in patients with a known hypersensitivity to Tiotropium Bromide or any inactive ingredient present in Tiova Rotacaps.

Overdose

High doses of Tiotropium may lead to anticholinergic signs and symptoms. However, there were no systemic anticholinergic adverse effects following a single inhaled dose of up to 282 mcg Tiotropium dry powder in 6 healthy volunteers. Dry mouth/throat and dry nasal mucosa occurred in a dose-dependent [10-40 mcg daily] manner, following 14-day dosing of up to 40 mcg tiotropium bromide inhalation solution in healthy subjects.
Treatment of overdosage consists of discontinuation of Tiova Rotacaps (Generic Tiotropium Bromide Rotacaps) together with institution of appropriate symptomatic and/or supportive therapy.

Warnings and Precautions to be taken when using Tiova Rotacaps

Medical History
Before beginning the treatment with Tiotropium Bromide Inhalation Powder, discuss your personal and family medical history with your doctor. Inform your doctor if you have difficulty urinating due to an enlarged prostate, blockage of the bladder neck, glaucoma, kidney problems, asthma attack, increased difficulty breathing, and stroke.
Allergy
Please inform your doctor if you have an allergy or have had an allergic reaction in the past to Tiotropium Bromide or any inactive ingredient in Tiova Rotacaps. Please tell your doctor if you have any other allergies.
Tiotropium Bromide Interactions
Before beginning the oral therapy of Tiotropium Bromide Inhalation Powder, please tell your doctor about all your present medications including prescription drugs, over the counter medications, mineral supplements, herbal products, and vitamins. Tiotropium Bromide Inhalation Powder are known to have drug interactions with certain other medications. Please inform your doctor if you are taking anticholinergics (ipratropium) because they may escalate the risk of side effects due to the administration of Tiova Rotacaps. Also, let me know if you are using medications such as atropine (Atreza, Sal-Tropine); belladonna (Donnatal, and others); benztropine (Cogentin); dimenhydrinate (Dramamine); methscopolamine (Pamine); scopolamine (Transderm-Scop); theophylline (Elixophyllin, Theo-24, Theochron, Uniphyl), and others; tiotropium (Spiriva); bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare); cough, cold, or allergy medicine; irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine); steroid medication such as prednisone (Deltasone, Sterapred), methylprednisolone (Medrol), fluticasone (Advair , Flonase, Flovent, Veramyst), beclomethasone (Qvar), budesonide (Pulmicort, Rhinocort, Symbicort), dexamethasone (Cortastat, Dexasone, Solurex, DexPak), mometasone (Asmanex, Nasonex), triamcinolone (Nasacort), and others; or ulcer medications such as glycopyrrolate (Robinul) or mepenzolate (Cantil).
Live Vaccinations, Surgery and Regular Medical Tests
If you plan to have live vaccinations, surgery or any dental procedure, inform your doctor, anesthetist, or dentist about your course of Tiova Rotacaps. In case of an emergency medical treatment, please inform the practitioner about your course of Tiotropium Bromide Inhalation Powder and the details of your last dose.

Side Effects of Tiova Rotacaps

The following side effects have been reported during the course of treatment with Tiotropium Bromide Inhalation Powder:

• Central Nervous System- confusion, sudden vision problems, or slurred speech
• Respiratory System- wheezing, chest pain or tightness, trouble breathing, mild to severe nose bleed, sinus inflammation, sore throat, unusual hoarseness, trouble swallowing, runny nose
• Gastrointestinal System- constipation, dry mouth, stomach pain, vomiting
• Urinary System- pain or burning sensation during urination
• Musculoskeletal System- muscle pain
• Hypersensitivity- rash, hives, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, tightness in the chest, skin redness
• General- one-sided weakness, fast or irregular heartbeat, irritation, mouth sores

Inform your doctor immediately if you experience any of these side effects. This is not an exhaustive list of all the potential side effects of Tiotropium Bromide Inhalation Powder. If you develop any other medical conditions during the course of treatment with Tiova Rotacaps please contact your doctor immediately.

Tiotropium Bromide Inhalation Powder (Tiova Rotacaps) During Pregnancy and Breastfeeding

Tiotropium Bromide Inhalation Powder has been classified by the US FDA as Pregnancy Category C.
The limited human data with tiotropium use during pregnancy are insufficient to inform a drug-associated risk of adverse pregnancy-related outcomes. Based on animal reproduction studies, no structural abnormalities were observed when Tiotropium was administered by inhalation to pregnant rats and rabbits during the period of organogenesis at doses 790 and 8 times, respectively, the maximum recommended human daily inhalation dose.
Tiotropium Bromide is not known to be transmitted to a baby through breastmilk. Pregnant women and breast feeding mothers who are undertaking treatment with Tiotropium Bromide Inhalation Powder (Tiova Rotacaps) should consult their doctor and comprehend its therapeutic benefits and associated risks before starting the course of treatment with Tiotropium Bromide Inhaler.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.Do not use this medication without telling your doctor if you are breast-feeding a baby.

Buy Tiotropium Bromide Inhalation Powder (Tiova 18 mcg Rotacaps) Online From Only $0.58 per Capsule

You can buy Tiotropium Bromide Inhalation Powder online from Everest Online Pharmacy at a cheap price. Tiova Rotacaps 18 mcg capsules, manufactured by Cipla, India are supplied in a bottle of 30 capsules. The 18 mcg capsules cost only $0.58 per unit when you place an order for 600 capsules.

Disclaimer

The above information is provided to the best of our knowledge and in good faith. It is without a warrant of any kind, expressed or implied.

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