Methylprednisolone Tablets

Methylprednisolone Tablets (Predmet) - Product Information

Predmet tablets contain the corticosteroid called methylprednisolone which prevents the release of inflammatory substances in the body.
It is used to treat a variety of medical conditions such as allergies, endocrine dysfunctions, skin problems, ophthalmic disorders, ulcerative colitis, arthritis, lupus, psoriasis, breathing problems, etc.
We also have in stock Levorid-D (Levocetirizine and Phenylephrine Tablets) which is also used treatment and prevention of cold, allergic rhinitis and hay fever.

Name of the Drug

Predmet Tablets. Methylprednisolone Tablets are also available under brand names such as Medrone Tablets, Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack.

Manufacturer of Predmet Tablets

Predmet Tablets are manufactured by Sun Pharmaceutical Industries Ltd.  
Website: www.sunpharma.com

Active Pharmaceutical Ingredient

The active ingredient present in Predmet tablets is Methylprednisolone.
Each Predmet tablet contains 2 mg, 4 mg, 8 mg or 16 mg of methylprednisolone. The inactive ingredients present in Predmet tablets are calcium stearate, corn starch, erythrosine sodium, lactose, mineral oil, sorbic acid, and sucrose.

What are Predmet Tablets Used For?

Methylprednisolone, the active ingredient in Predmet tablets is a corticosteroid hormone that is used for the treatment of many inflammatory conditions such as arthritis, systemic lupus erythematosus, multiple sclerosis, psoriasis, severe allergic disorders (allergic rhinitis , drug allergies, serum sickness, contact dermatitis, autoimmune haemolytic anaemia), gland disorders, certain cancers (lymphoma).
Predmet tablets are also used in conditions that affect the brain (meningitis), skin (eczema, pemphigus vulgaris, exfoliative dermatitis), eyes (optic neuritis, uveitis or iritis), heart (carditis), kidney, intestine, lungs (bronchial inflammation, asthma, tuberculosis, Sarcoidosis, gastric aspiration), stomach, bowel and gut (Crohn’s disease and ulcerative colitis), nervous system, muscle (dermatomyositis, polymyositis, and polymyalgia rheumatica), joints (rheumatoid arthritis, rheumatic fever, juvenile chronic arthritis, ankylosing spondylitis), blood and blood vessels (leukemia, giant cell arteritis).
Methylprednisolone also reduces the immune system reactions to various diseases such as swelling, pain, and allergic-type reactions. Methylprednisolone is used along with other medications to treat hormone disorders.
For example, Predmet tablets can be administered if the adrenal glands in the body are dysfunctional (adrenal insufficiency, congenital adrenal hyperplasia) and does not produce sufficient corticosteroid hormone.
The hormone corticosteroid is also useful in post-surgery recuperation (organ transplants) and in the treatment of injuries.

Methylprednisolone - Dosage

You should strictly follow the medication course for Methylprednisolone tablets (Predmet) as prescribed by your doctor because steroid hormones are used to treat different medical conditions. You doctor may sometimes alter your dosage to achieve the best possible results using the drug depending on your medical condition and your response to treatment.
Predmet tablets should be consumed during the morning time to imitate the adrenal gland’s natural secretion of corticosteroids. Methylprednisolone tablets should be taken after food to reduce stomach problems.
Make sure you stick to the doctor’s recommendations without increasing or decreasing the dosage levels and the dosage period. The lowest possible dosage of corticosteroid should be used to cure the medical condition under treatment. There are various problems that arise from the consumption of glucocorticoids medications. But these medical complications are dependent on the strength of the dose and the treatment period. These factors should be considered before making a decision about the patient’s therapy i.e. if the patient should consume the Predmet tablets every day or alternatingly.
When the dosage of Predmet tablets has to be lowered, the decrease in dosage should not be abrupt but it should be gradual and systematic. Consult your doctor about gradually decreasing the dosage levels of Predmet tablets towards the end of the medication course because abrupt discontinuation of Methylprednisolone tablets could lead to undesirable withdrawal symptoms.
Let your doctor know about any conditions such as serious illness, fever, infection, surgery, or any medical emergency that may develop during the medication course, so that the dosage can be modified accordingly.
Please consult your doctor for exact dosing instructions. Predmet tablets (Generic Methylprednisolone tablets) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Missed Dose

In case you miss a dose of methylprednisolone tablets, please consult your doctor immediately for further instructions.

Predmet Mechanism of Action – How Does Methylprednisolone Work?

Methylprednisolone is the active ingredient in Predmet tablets. It is a steroid, known as corticosteroids. Corticosteroids are essential hormones which are naturally made by the adrenal glands in the human body. Corticosteroid medications are artificial versions of the natural hormones. Methylprednisolone is a synthetic corticosteroid which inhibits the discharge of inflammatory substances in the body that occurs in different disorders. It acts as an anti-inflammatory substance by inhibiting certain immune system substances which are required for immune and allergic reactions such as inflammation.
When Methylprednisolone decreases the release of these chemicals in the body, it results in the reduction of inflammation. Methylprednisolone works efficaciously to reduce the characteristic inflammation in several disease states and allergic reactions.
Methylprednisolone also reduces the circulation of white blood cells present in blood and prevents its reaction against the presence of a foreign tissue in the body. This useful feature of Methylprednisolone is beneficial to avoid organ rejection during transplant procedures.
Methylprednisolone is also used for the treatment of leukemia which is characterized by the manifestation of unusually large number of white blood cells. It is also suitable for the treatment of autoimmune diseases in which body’s immune system attacks its own tissues.
Corticosteroids are vital to a wide variety of organ functions. Sometimes, dysfunctional adrenal glands may result in decreased level of steroid hormones in the body. Methylprednisolone can be used as replacement therapy to normalize the levels of the corticosteroid hormone in the body and to restore the organ functions dependent on them.

Storage

Store Methylprednisolone tablets (Predmet) at controlled room temperature (20°C to 25°C). Excursions are permitted from 15°C to 30°C.
Keep the pack of Predmet tablets protected from sunlight and moisture. Do not let children or pets anywhere near Predmet tablets. Do not consume Predmet tablets after its expiration date printed on the blister pack. Do not dispose Predmet tablets along with waste water or other domestic waste. Consult your pharmacist about the accurate steps to be taken for the appropriate disposal of Methylprednisolone tablets. Such measures will prove beneficial for the protection of the environment.

Contraindications

Patients consuming Predmet tablets may have contraindications during the course of medication if they are suffering from any systemic fungal infections or if they have a known hypersensitivity to Methylprednisolone or to any other inactive ingredient of Predmet tablets.

Warnings and Precautions to be taken when using Predmet Tablets

Before starting your medication of Predmet tablets (Methylprednisolone tablets), let your doctor know about your current prescription medicines, medical history, your allergies, and any other important information regarding your health. These factors will be important for the doctor to prescribe the correct dosage for your medical condition. Medical history
Consult your doctor before you start the course of Predmet tablets if you have a medical history of eye problems (cataracts, glaucoma, herpes infection of the eye), heart disease(recent heart attack, congestive heart failure), high blood pressure, kidney or liver disease (cirrhosis), peptic ulcer, blood clots, stomach problems (ulcerative colitis, diverticulitis), infections (tuberculosis, threadworm, herpes, fungus), parasite infection (pinworms), glaucoma or cataracts, a recent head injury, stomach / intestinal problems (ulcers, ulcerative colitis or diverticulitis), thyroid disorder, low bone mineral density (steroid medication can increase your risk of osteoporosis), depression or mental illness, muscle disorder (myasthenia gravis), seizures or epilepsy, bleeding issues, electrolyte imbalance (low levels of calcium or potassium in blood), high levels of calcium in the blood related to cancer (hypercalcemia of malignancy). You should inform your doctor if you consume insulin or oral diabetes medication, or aspirin on an everyday basis or at high doses.
Allergic reactions
If you have suffered an allergic reaction such as skin rash, reddening, swelling of face or lips, breathing problem from the use of Predmet tablets in the past, let your doctor know. You may be allergic to the active ingredient methylprednisolone or other inactive ingredients. Do not use Predmet tablets (Methylprednisolone tablets) if you are suffering from a fungal infection, especially untreated fungal infection in the lungs or esophagus.
Drug Interactions
While taking Predmet tablets, you should be aware of the drug interactions of steroids such as methylprednisolone with other drugs such as Acetazolamide, Anticholinesterases (distigmine and neostigmine), Antibiotics (erythromycin, clarithromycin and troleandomycin), aspirin(ibuprofen), diuretics (water tablets), anticoagulants or blood thinners (acenocoumarol, phenindione and warfarin), Aminoglutethimide or Cyclophosphamide (anti-cancer drugs), Barbiturates, carbamezipine, phenytoin and primidone, cyclosporines (Gengraf, Neoral, Sandimmune), Carbenoxolone and cimetidine, insulin or oral diabetes medication, Digoxin, Diltiazem or mibefradil , Ethinylestridiol and norethisterone, Indinavir or ritonavir, ketoconazole or itraconazole (Nizoral), Pancuronium or vercuronium, rifampin and rifabutin (Rifadin, Rifater, Rifamate, Rimactane), seizure medications (phenytoin (Dilantin) or phenobarbital (Solfoton)), Tacrolimus, or recent vaccination. Interaction of ingredients in grapefruit and grapefruit juice with the ingredients in methylprednisolone can lead to unwanted side effects. Do not use of grapefruit products during the medication period of methylprednisolone tablets (Predmet).
Growth in Children/Effects in Children
Steroids can upset the growth and development in children when used for long periods. Inform your doctor if you feel that your child is not growing at a normal rate during the course of Methylprednisolone tablets. Meet the doctor regularly to measure your child's body parameters such as height and weight.
Medication Course
Do not stop the course of Predmet tablets abruptly because it could lead to unpleasant consequences. Discuss with your doctor about how to avoid such conditions towards the end of the medication course.
Viral infection
If you are accidently exposed to patients suffering from viral infections such as chicken pox and measles during the course of treatment or even three months later, inform your doctor immediately and he will give you a shot of antibodies because you stand a risk of severe chicken pox symptoms if infected during treatment with methylprednisolone tablets. During the course of methylprednisolone medication, do not undergo vaccinations with live vaccines such as measles, mumps, rubella (MMR), rotavirus, typhoid, Bacillus Calmette-Guérin (BCG), oral polio, yellow fever, varicella (chickenpox), zoster (shingles), H1N1 influenza and nasal flu (influenza) because these vaccines may be ineffective during this time period and will not be protect you from the disease.
Alcohol consumption during medication period
Consumption of alcohol during the period of Methylprednisolone tablets medication can lead to the risks of dizziness and stomach bleeding. Talk to your doctor for more information.
Predmet tablets and Tuberculosis
The consumption of Methylprednisolone tablets in active tuberculosis patients should be limited to only fulminating or disseminated tuberculosis because the corticosteroid used for the treatment of an infection can be used in combination with a suitable antituberculous schedule. If corticosteroids are specified in patients with latent tuberculosis or tuberculin reactivity, strict surveillance is required as recurrence of the disease may follow. During extended corticosteroid treatment, such patients should obtain chemoprophylaxis.

Side Effects of Predmet Tablets

Steroid medications are known to weaken the immune system. This makes the patient susceptible to infections.
Let your doctor know immediately if you develop any symptoms of infection such as fever, chills, body ache, persistent sore throat, cough, and white patches inside the mouth during the course of Methylprednisolone tablets (Predmet).
During the course of methylprednisolone tablets, you may develop certain less serious side effects such as insomnia, mood swings, depression, agitation, suicidal thoughts, psychotic reactions (including mania, delusions and hallucinations), memory loss, lack of sleep, skin problems (acne, dryness, change in pigmentation, stretch marks, thinning of skin, bruising or discoloration), increased sweating, headache, light-headedness, dizziness, nausea, vomiting, heartburn, stomach discomfort, abdominal bloating, change in appetite, difference in shape or location of body fat in arms, legs, face, neck, breasts, and waist.
Some of the serious side effects of Predmet tablets include pancreatitis (severe inflammation and pain in upper stomach going all the way to your back, nausea and vomiting, increased heart rate); sodium and water retention; adrenal suppression; low potassium levels in the body (lack of clarity, irregular heart rate, extreme thirst, increased urination, uneasiness in legs, muscle weakness or flaccid sensation); or dangerously high blood pressure (severe headache, blurred vision, tunnel vision, eye pain, or imagining halos around lights buzzing sound in ears, anxiety, confusion, chest pain, shortness of breath, irregular heartbeat, seizure); High blood sugar (diabetes), problems with vision; puffy face, swelling of ankles, feet and hands, unusual hair and skin growth, abnormal weight gain, characteristic moon-shaped face (Cushing's syndrome), pain in bone and joints, menstrual irregularities, shortness of breath; severe depression, strange thoughts or behavioral changes, seizure (convulsions); bloody stools, coughing up blood or vomit that resembles coffee grounds; Blood clots in the blood vessels (thromboembolism). Call your doctor immediately if you notice such symptoms during the course of your medication.
This may not be a comprehensive list of all the possible side effects of Methylprednisolone tablets. For additional information about the side effects of Predmet tablets, consult your doctor or pharmacist.

Methylprednisolone Tablets (Predmet) During Pregnancy and Breastfeeding

Methylprednisolone Tablets (Predmet) has been classified by the US FDA as Pregnancy Category C .
Some animal studies have shown that corticosteroids, when administered to the mother at high doses, may cause foetal malformation.
Consult your doctor if you plan to start a family or have become pregnant during the course of the medication of Methylprednisolone tablets (Predmet) because it is important to avoid abrupt discontinuation of medication.
Long periods of Methylprednisolone tablets consumption during pregnancy can slow the growth and development of the fetus. The new born baby may also have lower levels of steroid hormone in its body although this may not pose to be a grave problem in future.
Breast feeding mothers on Methylprednisolone tablets should consult their doctor because small amount of corticosteroids can pass through the breast milk to the infant.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.

Buy Methylprednisolone 4 mg, 8 mg and 16 mg Pills (Predmet) Online From Only $0.30 per Pill

You can buy Methylprednisolone tablets online from Everest Online Pharmacy at a cheap price. Predmet 4 mg, 8 mg and 16 mg pills, manufactured by Sun Pharmaceutical Industries Ltd. , India, are supplied in a blister strip of 10 tablets. The 4 mg tablets cost only $0.30 a pill when you place an order for 360 pills.

Disclaimer

The above information is provided to the best of our knowledge and in good faith. It is without a warrant of any kind, expressed or implied.

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