Mesalamine Prolonged Release Tablets

Mesacol OD Tablets (Mesalamine Prolonged Release Tablets) - Product Information

Mesacol OD (orally disintegrating) Tablets contains Mesalamine as the active ingredient in the form of a prolonged release tablet. Mesalamine is an anti-inflammatory substance which belongs to a class of medications known as aminosalicylate. Mesacol OD Tablets are used to control inflammation in the bowel which is characteristic in certain medical conditions. Mesacol OD Tablets have a mechanism of action which is similar to aspirin.
Mesalamine OD Tablets (Mesacol OD) are prescribed as oral therapy for the treatment and prevention of the bowel disease called ulcerative colitis which has a characteristic intestinal inflammation accompanied by other symptoms such as ulceration and bleeding.
Mesalamine effectively acts on epithelial cells of the colon to control the production and consequent discharge of substances which cause inflammation, pain, swelling, tissue damage, and diarrhea. Mesacol OD Tablets are also recommended for the treatment of Crohn's disease, which is characterized by the inflammation of a part of the gastro-intestinal system.
Mesalamine are usually available in the market in various forms such as tablets, granules, rectal suppositories, rectal foam, and rectal enemas. In our online pharmacy, Mesacol OD Tablets are available in the strength of 1200 mg of Mesalamine.
We also have in stock Lansoprazole Capsules (Lan 15 mg & 30 mg Capsules) which is also used for the treatment and prevention of stomach and intestinal ulcers, erosive esophagitis, and other medical conditions that develop due to the presence of excessive acid in the stomach.

Name of the Drug

Mesacol OD Tablets.
Other brand names for Mesalamine OD Tablets include Mezavant. Mesacol OD Tablets are also commonly known as Generic Mesalamine OD Tablets.

Manufacturer of Mesacol OD Tablets

Mesacol OD Tablets, available in our online pharmacy are manufactured by Sun Pharmaceutical Industries Limited, India .
Mesacol OD Tablets are also known as Generic Mesalamine Prolonged Release Tablets.  
Website: www.sunpharma.com

Active Pharmaceutical Ingredient

The active ingredient present in Mesacol OD Tablets is Mesalamine. Each Mesacol OD tablet contains 1200 mg of Mesalamine.
The inactive ingredients present in Mesacol pills are carmellose sodium, carnauba wax, stearic acid, silicon dioxide, sodium starch glycollate, talc-purified, magnesium stearate, methacrylic acid copolymer, triethyl citrate, titanium dioxide (e171), iron oxide red (ci77491), macrogol 6000.

What are Mesacol OD Tablets Used For?

Mesacol OD Tablets, manufactured by Sun Pharma, contain Mesalamine which is an anti-inflammatory substance. Mesalamine belongs to the aminosalicylates class of medications lessens the swelling in the colon. Mesacol OD Tablets are typically administered as oral therapy for the treatment and prevention of ulcerative colitis which is characterized by the inflammation, swelling and presence of sores along the lining of the colon and rectum.
The symptoms of ulcerative colitis include bleeding, abdominal pain, and diarrhea.
Mesacol OD Tablets do not actually cure ulcerative colitis, but, instead control the intensity of the inflammatory symptoms caused by irritation and swelling in the colon and rectal area. Mesacol OD Tablets are used to decrease inflammation, pain, swelling, tissue damage, and diarrhea by acting on epithelial cells of the colon to control the production and subsequent release of substances which cause these symptoms. Mesacol OD Tablets are also useful to prevent the recurrence of ulcerative colitis symptoms. Mesacol OD Tablets are beneficial for the treatment of swelling and inflammations of the rectum and colon.
Treatment with Mesalamine 1.2 g Tablets (Mesacol) is also recommended for the treatment of another inflammatory condition of the gastro-intestinal system called Crohn's disease.

Mesacol OD Dosage - How to Take Mesalamine OD Tablets?

You should use Mesacol OD Tablets exactly as recommended by your doctor. Your doctor may suggest a dosage of Mesacol OD Tablets depending on the severity of your medical condition, body weight, other medical conditions, and current medications.
Mesacol OD Tablets should be taken along with a glass of water, after a meal to avoid indigestion. Avoid chewing or crushing the Mesacol OD tablet in your mouth because it can interfere with the effectiveness of the drug. Try to maintain a regular schedule for the medication such that you take Mesacol OD Tablets at the same time every day, to get the maximum benefit of the medication.
The recommended daily dosage of Mesacol OD Tablets for the treatment of active ulcerative colitis is 4 g which can be taken once a day or divided into several doses. Your doctor may alter the dosage of Mesacol OD Tablets and dosage period depending on the type and severity of your condition and your response to treatment. The suggested daily dose of Mesacol OD Tablets for the long term treatment of ulcerative colitis is 2 g which can be taken once a day or divided into multiple doses.
The optimal daily dosage of Mesacol OD Tablets for the treatment of Crohn’s disease is 4 g divided into several doses during the day. The recommended dosage of Mesacol OD Tablets for the long term treatment of Crohn’s disease is 4 g divided into several doses during the day.
It is imperative that you complete the recommended course of treatment with Mesacol OD Tablets as advised by the doctor. Mesacol OD tablets does not cure the medical conditions but merely controls the symptoms. Discontinuing the treatment course early will increase the risk of the recurrence of inflammatory symptoms.
Please consult your doctor for exact dosing instructions. Mesacol OD tablets (Generic Mesalamine prolonged release tablets) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Missed Dose

If you miss your regular dose of Mesacol OD Tablets (Generic Mesalamine Prolonged Release Tablets), take it as soon as you remember. You can continue your regular schedule the next day. If you remember the missed Mesacol OD Tablets the next day, take your regular dose and skip the missed dose.
Do not take a double dose to compensate the missed dose.

Mesacol Mechanism of Action – How Does Mesalamine OD Work?

Mesalamine is an anti-inflammatory agent which belongs to the aminosalicylates class of medications. Mesalamine is the active element of the compound called sulfasalazine. Upon bacterial action in the colon, Sulfasalazine gets separated into Sulfapyridine and Mesalamine.
Mesacol OD Tablets (Generic Mesalamine OD Tablets) are used to treat the inflammatory conditions of the digestive tract, ulcerative colitis, and Crohn's disease. During ulcerative colitis, there is an uncontrolled production of inflammation-inducing chemicals such as prostaglandins the colon. Prostaglandins are released due to enzymatic actions of cyclooxygenase and lipoxygenase enzymes. Patients with ulcerative colitis are found to have a high level of these enzymes in their blood.
Mesalamine acts on the intestinal epithelial cells lining the organ which are responsible for the production of cyclooxygenase and lipoxygenase enzymes, preventing them from producing and secreting natural chemical substances such as prostaglandins which cause inflammation and related symptoms.
This suppressive mechanism of prostaglandin production decreases inflammation and allows the intestine to recover from the inflammatory damage, thereby preventing the recurrence of the inflammatory symptoms.

Storage Instructions for Mesacol OD Tablets

Store Mesacol OD Tablets at controlled room temperature (20°C to 25°C), protected from heat, moisture, and sunlight. Excursions are permitted from 15°C to 30°C.
Retain the original packing of the medication and do not consume Mesalamine 1.2 g Tablets beyond its expiration date printed on the blister pack. Keep Mesacol OD Tablets away from the reach of children and pets.
Do not discard Mesacol OD Tablets along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.

Contraindications

The treatment with Mesacol OD Tablets is contraindicated in patients who are allergic to Mesalamine, salicylates and sulfasalazine or any inactive ingredients present in Mesacol OD Tablets. Mesacol OD Tablets are also contraindicated in patients with severe impaired renal or hepatic function.
Children below the age of 18 years should not be administered Mesacol OD Tablets because there are no studies to confirm its safety and efficacy in the patients in this age group.

Overdose

Mesalamine is an aminosalicylate, and symptoms of salicylate toxicity include nausea, vomiting and abdominal pain, tachypnea, hyperpnea, tinnitus, and neurologic symptoms (headache, dizziness, confusion, seizures).
There is no specific antidote for mesalamine overdose; however, conventional therapy for salicylate toxicity may be beneficial in the event of acute overdosage and may include gastrointestinal tract decontamination to prevent of further absorption. Correct fluid and electrolyte imbalance by the administration of appropriate intravenous therapy and maintain adequate renal function.

Warnings and Precautions to be taken when using Mesacol OD Tablets

Medical History
Before beginning the treatment with Mesacol OD Tablets (Generic Mesalamine OD Tablets), discuss your personal and family medical history with your doctor. Inform your doctor if you have any allergies, asthma, gastrointestinal conditions (stomach, heart, kidney, liver, and pancreas), pericarditis, myocariditis, and congestive heart failure.
Allergy
Please inform your doctor if you have an allergy or have had an allergic reaction in the past to Mesalamine; balsalazide (Colazal, Giazo); olsalazine (Dipentum); salicylate pain relievers such as aspirin, choline magnesium trisalicylate, diflunisal, magnesium salicylate (Doan's, others); sulfasalazine (Azulfidine)any inactive ingredient in Mesacol OD Tablets (Generic Mesalamine OD Tablets).
Mesalamine OD Interactions
Before beginning the oral therapy of Mesacol OD Tablets, please inform your doctor of all your current medications including prescription drugs, over the counter medications, mineral supplements, herbal products, and vitamins. Mesacol OD is known to have drug interactions with anti-coagulants (warfarin); glucocorticoids (prednisolone); sulphonylureas (glibenclamide, glipizide); methotrexate; probenicid or sulfinpyrazone; spirinolactone ; rifampicin; azathioprine; mercaptopurine and thioguanine.
Mesacol OD Tablets and Alcohol
Avoid alcohol consumption during the course of treatment with Mesacol OD Tablets.
Surgery and Regular Medical Tests
If you plan to have surgery or any dental procedure, inform your doctor, anesthetist, or dentist about your course of Mesacol OD Tablets (Generic Mesalamine OD Tablets). In case of an emergency medical treatment, please inform the practitioner about your course of Mesacol OD Tablets and the details of your last dose.

Side Effects of Mesacol OD Tablets

The following side effects have been reported during the course of treatment with Mesacol 1200 mg tablets (Generic Mesalamine Prolonged Release Tablets):

• Cardiovascular System- chest pain, myocarditis, pre-existing pericarditis
• Central Nervous System- headache, dizziness.
• Eye and ENT- sore throat, dry mouth, ear pain, nosebleeds.
• Gastrointestinal System- nausea, vomiting, bloating, abnormal gas, diarrhea, constipation, indigestion, stomach cramps, bloody diarrhea, abdominal pain, severe upper stomach pain, pancreatitis, nephritis, hepatitis, increased liver enzyme values, heartburn, burping.
• Genitourinary System- hemorrhoids, rectal pain, uterine tract infection, black or tarry stools.
• Musculoskelatal System- joint pain, back pain, myalgia, arthralgia.
• Hypersensitivity- rash, itching, shortness of breath.
• General- weight gain, fatigue, acne, hair loss, fever, yellowing of skin or eyes, intolerance syndrome, peripheral oedema, loss of appetite, blood disorders.

Inform your doctor immediately if you experience any of these side effects. This is not a comprehensive list of all the possible side effects of Mesacol OD Tablets (Generic Mesalamine OD Tablets). If you develop any other medical conditions during the course of treatment with Mesacol OD Tablets, please consult your doctor immediately.

Mesalamine Prolonged Release Tablets During Pregnancy and Breastfeeding

Mesalamine Prolonged Release Tablets (Mesacol OD Tablets) has been classified by the US FDA as Pregnancy Category C.
There may be a decrease in the fertility rate of women during the course of treatment with Mesacol OD. The risk of administering Mesacol OD Tablets to pregnant women should be discussed with the doctor. Low concentrations of Mesalamine is found to be transmitted through breast milk. Women should make it a point to consult their doctor and practice caution in decisions of pregnancy and breastfeeding during the course of Mesacol OD Tablets.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.

Buy Mesalamine Prolonged Release Tablets (Mesacol OD Tablets) Online at Only $1.56 per Pill

You can buy Mesalamine Prolonged Release Tablets online from Everest Online Pharmacy at a cheap price.
Mesacol OD Tablets 1.2 grams pills, manufactured by Sun Pharmaceutical Industries Limited, India are supplied in a blister strip of 10 tablets. The 1200 mg tablets cost only $1.56 per unit when you place an order for 600 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith. It is without a warrant of any kind, expressed or implied.

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