Doxycycline Hyclate And Lactic Acid Bacillus

Generic Doxycycline Hyclate and Lactic Acid Capsules (Doxt-SL Capsules) - Product Information

Doxt-SL Capsules contain Doxycycline Hyclate and Lactic Acid Bacillus as the active ingredients. Doxt-SL Capsules belong to a class of medications known as tetracycline antibiotics which are prescribed as oral therapy for the effective treatment and prevention of various bacterial infections in adults and children. Doxt-SL Capsules are used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, gum infections, and sexually transmitted infections (like gonorrhoea and syphilis).
Doxycycline Hyclate is a popular antibiotic because it is effective against a broad-spectrum of gram-positive and gram-negative bacteria.
Generic Doxycycline Hyclate Capsules are often used for the treatment of bacterial infection of the respiratory tract, ears, lung, stomach, urinary tract, gums (periodontitis) and skin (blemishes, bumps, acne). Doxycycline Hyclate Capsules are also effective in the treatment of sexually transmitted diseases (syphilis, gonorrhea, and chlamydia) and rickettsial infections (Q fever or tick fever).
Doxycycline Hyclate Capsules are used as therapy for the treatment of other infections such as malaria, cholera, brucellosis, psittacosis and fevers caused by lice or ticks. Doxt-SL Capsules are also preferred as a preventive measure for traveler's diarrhea, scrub typhus and leptospirosis.
In our online pharmacy, Doxt-SL Capsules, manufactured by Dr. Reddy's Laboratories Limited, India , are available in the strength of 100 mg of Doxycycline.
We also have in stock Ciplox Capsules (Generic Ciprofloxacin) which are prescribed as oral therapy for the effective treatment of various types of bacterial infections of the eye, ears, teeth, chest, prostate, digestive system, bone and joint. Ciprofloxacin HCl Capsules are also effective for the treatment of urine tract infections (UTI) and sexually transmitted infections/disease (STD).

Name of the Drug

Doxt-SL Capsules.
Doxt-SL capsules are also available under different brand names such as Vibramycin Capsules.

Manufacturer of Doxt-SL Capsules

Doxt-SL Capsules, available in our online pharmacy are manufactured by Dr. Reddy's Laboratories Limited, India  
Website: www.drreddys.com

Active Pharmaceutical Ingredient

The active ingredient present in Doxt-SL Capsules are Doxycycline Hyclate and Lactic Acid Bacillus. Each Doxt-SL capsule contains Doxycycline Hydrochloride equivalent to 100 mg of Doxycycline. It also contains 5 billion spores of Lactic Acid Bacillus (as Enteric coated pellets).

What are Doxycycline Hyclate Capsules Used For?

Doxycycline Hyclate and Lactic Acid Bacillus Capsules (Doxt-SL Capsules) are used for the treatment of bacterial infections in many different parts of the body. Doxycycline is used to treat bacterial infections of the respiratory tract, ears, lung, stomach, urinary tract, gums and skin. They are also effective in the treatment of sexually transmitted diseases. It is also used to treat pimples and abscesses (usually on the face) that are caused by rosacea, also known as acne rosacea or adult acne.Doxycycline capsules, are also used to prevent malaria and treat anthrax infection after possible exposure and other conditions as determined by your doctor. Doxycycline belongs to the class of medicines known as tetracycline antibiotics. It works by killing bacteria or preventing their growth.
Doxycycline Hyclate Capsules are also used to treat the incidence of ophthalmic (eye) infections caused by gonococci, staphylococci and Haemophilus influenzae; rickettsial infections such as rocky Mountain spotted fever, typhus group, Q fever, Coxiella endocarditis and tick fevers, other infections such as Psittacosis, cholera, meliodosis, leptospirosis, lyme disease; infections caused due to Yersinia species, Brucella species (in combination with Streptomycin), Clostridium species, Francisella tularensis and chloroquine-resistant falciparum malaria. Doxycycline Hyclate 100 mg Capsules are also used in the prophylaxis of Scrub typhus, traveler's diarrhea (enterotoxigenic Escherichia coli), and leptospirosis.
Doxt-SL 100 mg Capsules cannot be used in the treatment of viral infections such as common cold and flu.

Doxt-SL Dosage - How to Take Doxycycline Hyclate Capsules?

Generic Doxycycline Hyclate and Lactic Acid Capsules should be administered exactly as suggested by your doctor. Your doctor may recommend a dosage of Doxt-SL Capsules depending on your medical requirement, body weight, other medical conditions, and current medications. Dox Capsules should be taken once a day with a glass of water or milk or even food to avoid gastrointestinal problems.
Doxycycline Hyclate Capsules should be consumed when the patient is sitting or standing. You should not lie down and continue to maintain an upright position for almost 30 minutes after the administration of Doxycycline Hyclate Capsules.
You should be systematic about the daily schedule for the medication such that you take Doxt-SL Capsules at the same time every day, to get the maximum benefit of the medication. The general treatment period of Doxycycline Hyclate Capsules is a minimum of 10 days. Your doctor may modify the dosage of Generic Capsules and treatment period depending on your response to treatment. Continue taking Dox Capsules for the recommended treatment period without missing any doses. Do not stop the treatment temporarily even if you feel that your symptoms have cleared because the infection can reoccur with symptoms which be more difficult to treat due to antibiotic resistance of the bacteria.
Patients on a treatment with Doxycycline 100 mg Capsules should consume adequate amount of fluids to reduce the risk of esophageal irritation and ulceration.
General Dosing Information
Adults:
The usual dose of oral Doxycycline is 200 mg on the first day of treatment (administered 100 mg every 12 hours) followed by a maintenance dose of 100 mg daily. In the management of more severe infections (particularly chronic infections of the urinary tract), 100 mg every 12 hours is recommended.
For children above 8 years of age:
The recommended dosage schedule for children weighing 45 kg or less is 4.4 mg/kg of body weight divided into two doses on the first day of treatment, followed by 2.2 mg/kg of body weight given as a single daily dose or divided into two doses on subsequent days. For more severe infections up to 4.4 mg/kg of body weight may be used. For children over 45 kg, the usual adult dose should be used.
Administration of adequate amounts of fluid along with the capsules is recommended to wash down the capsule to reduce the risk of esophageal irritation and ulceration.
Doxycycline Hyclate Capsules Dosage for Infection
The standard recommended starting dose for infections is 200 mg of Doxycycline Hyclate Capsules on the first day of treatment, followed by a dosage of 100 mg of Dox Capsules, once daily in both children above the age of 12 years and adults. Depending on the severity of the infection, the dosage can be increased to 200 mg. The administration of doses higher than the recommended dosage can result in the development of side effects. When Dox 100 mg Capsules are used in the treatment of streptococcal infections (strep throat), the treatment period should be 10 days, to prevent the probability of rheumatic fever or glomerulonephritis.
Doxycycline Hyclate Capsules Dosage for Acne
The recommended dosage for the treatment of skin problems such as acne vulgaris is 50 mg, once a day for about 6-12 weeks.
Doxycycline Hyclate Capsules Dosage for STD
The optimal dose for the treatment of sexually transmitted disease (STD) is 100 mg twice a day, for about 7-10 days.
Doxycycline Hyclate Capsules Dosage for Primary and Secondary Syphilis
The ideal dosage for the treatment of syphilis is 300 mg a day, which can be divided into multiple doses for a period of 10 days.
Doxycycline Hyclate Capsules Dosage for Fevers due to Lice or Ticks
The recommended dosage for the treatment of fevers caused by the presence of lice or ticks is a single dose of 100 mg or 200 mg of Dox Capsules, depending on the severity of the fever.
Doxycycline Hyclate Capsules Dosage for Malaria
Dox Capsules are usually administered along with quinine drugs for the treatment of malaria. The optimal dose for the treatment of Dox Capsules for malaria is 200 mg per day for a period of 7 days.
Doxycycline Hyclate Capsules Dosage for Scrub Typhus
The ideal dosage for the prevention of scrub typhus is a single dose of 200 mg of Dox Capsules.
Doxycycline Hyclate Capsules Dosage for Traveler's Diarrhea
The recommended dosage for the prevention of traveler's diarrhea is 200 mg on the first day of travel followed by a dosage of 100 mg per day for the remaining days. You should be careful to not administer Dox Capsules for more than three weeks of treatment, unless your doctor has instructed you otherwise.
Doxycycline Hyclate Capsules Dosage for Leptospirosis Infections
The optimal dose for the prevention of leptospirosis infections is 200 mg of Dox Capsules administered once a week during the stay in an infected area, followed by a dosage of 200 mg at the end of the trip. You should be careful to not administer Dox Capsules for more than three weeks of treatment, unless your doctor has instructed you otherwise.
Please consult your doctor for exact dosing instructions. Capsules (Generic Capsules) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Missed Dose

If you miss your regular dose of Generic Doxycycline and Lactic Acid Capsules, take it as soon as you remember. You can continue your regular schedule the next day. If you remember the missed Doxycycline Hyclate Capsules the next day, take your regular dose and skip the missed dose.
Do not take a double dose to compensate the missed dose.

Doxt-SL  Mechanism of Action - How Does Doxycycline Hyclate Work?

Doxycycline Hyclate is a tetracycline antibiotic which is used to treat a broad spectrum of bacterial infections caused by gram positive and gram negative bacteria.
Doxt-SL Capsules are bacteriostatic medications i.e. they do not kill the bacteria but rather stop or prevent the growth of bacteria by inhibiting its protein synthesis.

Storage Instructions for Doxt-SL Capsules

Store the pack of Doxycycline Hyclate Capsules at controlled room temperature (20°C to 25°C), protected from heat, moisture, and sunlight. Excursions permitted to 15°C to 30°C.
Retain the original packing of the medication and do not consume Doxycycline Hyclate Capsules (Doxt-SL ) beyond its expiration date printed on the blister pack. Keep the pack of Generic Doxycycline Hyclate Capsules away from the reach of children and pets. Do not discard Generic Doxycycline Hyclate and Lactic Acid Capsules (Doxt-SL Capsules) along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.

Contraindications

Doxt-SL Capsules are contraindicated in patients with a known hypersensitivity to Doxycycline Hyclate, minocycline, tetracycline, sulfites, or any inactive ingredient present in Doxt-SL capsules. Doxt-SL Capsules should not be administered in children below the age of 12 years because it results in the permanent discoloration of tooth enamel and also disturbs bone development.
Doxycycline Hyclate Capsules are contraindicated in patients who have a hereditary condition of sucrose intolerance, glucose galactose malabsorption or sucrose-isomaltase insufficiency.
Pregnant women should not use Doxycycline Hyclate Capsules for treatment of infections because it causes permanent tooth discoloration in the fetus towards the last trimester of pregnancy (teeth development phase). Nursing mother should avoid the use of Doxt-SL capsules because Doxycycline Hyclate is known to be secreted through milk resulting in tooth and bone problems in infants.

Doxycycline Hyclate Capsules - Overdose

Acute over dosage with tetracycline antibiotics is generally uncommon. If you administer an overdose of Doxycycline Hyclate Capsules, please seek emergency medical help immediately and discontinue the course of medication.

Warnings and Precautions to be taken when using Doxycycline Hyclate Capsules

Tooth Development
The use of Doxycycline Hyclate during tooth development (last half of pregnancy, infancy and childhood to the age of 8 years) may cause permanent discoloration of the teeth (yellow-gray-brown). This adverse reaction is more common during long-term use of the drugs of the tetracycline class, but it has been observed following repeated short-term courses. Enamel hypoplasia has also been reported with drugs of the tetracycline class. Advise the patient of the potential risk to the fetus if Doxycycline Hyclate is used during pregnancy.
Use Doxycycline Hyclate in pediatric patients 8 years of age or less only when the potential benefits are expected to outweigh the risks in severe or life-threatening conditions (e.g., anthrax, Rocky Mountain spotted fever), particularly when there are no alternative therapies.
Inhibition of Bone Growth
The use of Doxycycline Hyclate during the second and third trimester of pregnancy, infancy and childhood up to the age of 8 years may cause reversible inhibition of bone growth. All tetracyclines form a stable calcium complex in any bone-forming tissue. A decrease in fibula growth rate has been observed in premature infants given oral tetracycline in doses of 25 mg/kg every 6 hours. This reaction was shown to be reversible when the drug was discontinued. Advise the patient of the potential risk to the fetus if Doxycycline Hyclate tablets and capsules are used during pregnancy
Clostridioides difficile Associated Diarrhea
Clostridioides difficileassociated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including Doxycycline Hyclate , and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile.
C. difficile produces toxins A and B which contribute to the development of CDAD. Hypertoxin producing strains of C. difficilecause increased morbidity and mortality, as these infections can be refractory to antibacterial therapy and may require colectomy. CDAD must be considered in all patients who present with diarrhea following antibacterial use. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents.
If CDAD is suspected or confirmed, ongoing antibacterial use not directed against C. difficilemay need to be discontinued. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C. difficile,and surgical evaluation should be instituted as clinically indicated.
Photosensitivity
Photosensitivity manifested by an exaggerated sunburn reaction has been observed in some individuals taking tetracyclines. Patients apt to be exposed to direct sunlight or ultraviolet light should be advised that this reaction can occur with tetracycline drugs, and treatment should be discontinued at the first evidence of skin erythema.
Severe Skin Reactions
Severe skin reactions, such as exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms (DRESS) have been reported in patients receiving doxycycline. Fixed drug eruptions have occurred with doxycycline and have been associated with worsening severity upon subsequent administrations, including generalized bullous fixed drug eruption. If severe skin reactions occur, discontinue Doxycycline Hyclate tablets and Doxycycline Hyclate capsules immediately and institute appropriate therapy.
Intracranial Hypertension
Intracranial hypertension (IH, pseudotumor cerebri) has been associated with the use of tetracyclines including Doxycycline Hyclate. Clinical manifestations of IH include headache, blurred vision, diplopia, and vision loss; papilledema can be found on fundoscopy. Women of childbearing age who are overweight or have a history of IH are at greater risk for developing tetracycline associated IH. Concomitant use of isotretinoin and Doxycycline Hyclate should be avoided because isotretinoin is also known to cause pseudotumor cerebri.
Although IH typically resolves after discontinuation of treatment, the possibility for permanent visual loss exists. If visual disturbance occurs during treatment, prompt ophthalmologic evaluation is warranted. Since intracranial pressure can remain elevated for weeks after drug cessation patients should be monitored until they stabilize.
Antianabolic Action
The antianabolic action of the tetracyclines may cause an increase in BUN. Studies to date indicate that this does not occur with the use of doxycycline in patients with impaired renal function.
Incomplete Suppression of Malaria
Doxycycline offers substantial but not complete suppression of the asexual blood stages of Plasmodiumstrains.
Doxycycline does not suppress P. falciparum'ssexual blood stage gametocytes. Subjects completing this prophylactic regimen may still transmit the infection to mosquitoes outside endemic areas.
Development of Drug-Resistant Bacteria
Prescribing Doxycycline Hyclate in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.
Potential for Microbial Overgrowth
Doxycycline Hyclate may result in overgrowth of non-susceptible organisms, including fungi. If such infections occur, discontinue use and institute appropriate therapy.
Laboratory Monitoring for Long-Term Therapy
In long-term therapy, periodic laboratory evaluation of organ systems, including hematopoietic, renal and hepatic studies should be performed.
In case of an emergency medical treatment, please inform the practitioner about your course of Doxycycline Hyclate Capsules and the details of your last dose.

Side Effects of Doxt-SL Capsules (Doxycycline Hyclate and Lactic Acid Bacillus)

: The following side effects were observed in controlled clinical trials of Doxycycline in adult subjects with mild to moderate rosacea at a rate of 1% or more:
Nasopharyngitis, Pharyngolaryngeal Pain, Sinusitis, Nasal Congestion, Fungal Infection, Influenza, Diarrhea, Abdominal Pain Upper, Abdominal Distention , Abdominal Pain, Stomach Discomfort , Dry Mouth, Hypertension, Blood Pressure Increase, Aspartate Aminotransferase Increase, Blood Lactate Dehydrogenase Increase, Blood Glucose Increase, Anxiety, Pain , Back Pain and Sinus Headache .
Adverse Reactions for Tetracyclines: The following adverse reactions have been observed in patients receiving Tetracyclines at higher, antimicrobial doses:
Gastrointestinal:
anorexia, nausea, vomiting, diarrhea, glossitis, dysphagia, enterocolitis, and inflammatory lesions (with vaginal candidiasis) in the anogenital region. Hepatotoxicity. Esophagitis and esophageal ulcerations have been reported in patients receiving the capsule forms of the drugs in the tetracycline-class. Most of the patients experiencing esophagitis and/or esophageal ulceration took their medication immediately before lying down.
Renal toxicity:
Rise in BUN has been reported and is apparently dose-related
Skin:
maculopapular and erythematous rashes. Exfoliative dermatitis. Photosensitivity.
Hypersensitivity reactions:
urticaria, angioneurotic edema, anaphylaxis, anaphylactoid purpura, serum sickness, pericarditis, and exacerbation of systemic lupus erythematosus.
Blood:
Hemolytic anemia, thrombocytopenia, neutropenia, and eosinophilia
Inform your doctor immediately if you experience any of these side effects. This is not a complete list of all the possible side effects of . If you develop any other medical conditions during the course of treatment with Doxycycline Hyclate Capsules, please consult your doctor immediately.

Doxycycline Hyclate Capsules during Pregnancy and Breastfeeding

Doxycycline Hyclate is a Pregnancy Category D drug and the consequence of its administration is harmful to the unborn fetus because it results in the abnormal tooth and bone development.
Doxycycline hyclate, like other tetracycline-class antibacterial drugs, may cause discoloration deciduous teeth, and reversible inhibition of bone growth when administered during the second and third trimester of pregnancy. Available data from published studies over decades have not shown a difference in major birth defect risk compared to unexposed pregnancies with Doxycycline exposure in the first trimester of pregnancy. There are no available data on the risk of miscarriage following exposure to doxycycline in pregnancy. Advise the patient of the potential risk to the fetus if doxycycline hyclate is used during pregnancy.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.

Nursing Considerations

Tetracyclines are excreted in human milk, however, the extent of absorption of tetracyclines, including Doxycycline Hyclate (Doxt-SL Capsules), by the breastfed infant is not known. Short-term use by lactating women is not necessarily contraindicated; however, the effects of prolonged exposure to doxycycline in breast milk are unknown. Because of the potential for adverse reactions in nursing infants from doxycycline, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother
Do not use this medication without telling your doctor if you are breast-feeding a baby.

Buy Doxycycline Hyclate Capsules (Doxt-SL 100 mg Capsules) Online at Only $0.49 per Pill

You can buy Doxycycline Hyclate Capsules online from Everest Online Pharmacy at a cheap price. Doxt-SL 100 mg pills (Doxycycline Hyclate and Lactic Acid Bacillus), manufactured by Dr. Reddy's Laboratories, India, are supplied in a blister strip of 10 capsules. The 100 mg capsules cost only $0.49 per unit when you place an order for 240 capsules.

Disclaimer

The above information is provided to the best of our knowledge and in good faith, it is without a warrant of any kind, expressed or implied.

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