Depo Provera Contraceptive Injection

Depo Provera Contraceptive Injection - Product Information

Depo Provera Shot (Depo Provera CI 150mg) is a contraceptive injection which contains Medroxyprogesterone Acetate as the active ingredient. Medroxyprogesterone Acetate is the synthetic form of the female hormone, progesterone, which prevents the occurrence of ovulation. Depo Provera Shot is prescribed as intravenous therapy for the effective prevention of pregnancy in women.
Depo Provera Contraceptive Injections are an effective and safe method of birth control. Depo Provera Contraceptive Injection also alters the cervical mucus, making it difficult for the sperm to reach the uterus. Depo Provera Contraceptive Injection also modifies the uterine lining, resulting in the inability of the fertilized egg to attach to the uterus. The contraceptive impact of a single shot of Depo Provera Contraceptive Injection lasts for 12 weeks.
Depo Provera Contraceptive Injection is also used to alleviate the pain experienced by women during endometriosis. Depo Provera Contraceptive Injection is also indicated in the treatment of pain and certain symptoms prevalent in certain types of cancer such as breast cancer, kidney cancer, and cancer of the endometrium. In our online pharmacy, Depo-Provera Injection is available as a 1 ml vial, each containing 1 ml of Medroxyprogesterone Acetate sterile aqueous suspension 150 mg/ml.

Drug Name

Depo Provera Contraceptive Injection. Depo Provera Contraceptive Shot are also known as Medroxyprogesterone Acetate Injectable Suspension USP.

Manufacturer of Depo Provera Contraceptive Injection

Depo Provera Contraceptive Injection, available in our online pharmacy  is manufactured by Pfizer (in Belgium)
(Website: www. pfizer.com)

Active Pharmaceutical Ingredient

The active pharmaceutical ingredient in Depo Provera Shot is Medroxyprogesterone Acetate. Each 1 ml vial of Depo Provera Shot contains Medroxyprogesterone Acetate sterile aqueous suspension 150 mg/ml.
The inactive ingredients present in Depo Provera Shot are Polyethylene glycol, Polysorbate 80, Sodium chloride, Methylparaben, Propylparaben, and water for injection.

Depo Provera Shot Indications - What is Depo Provera Contraceptive Injection Used For?

Depo Provera Contraceptive Injection, manufactured by Pfizer, contains the synthetic version of the female hormone called progesterone. Depo Provera Contraceptive Injection is commonly administered for the effective prevention of pregnancy in women. Depo Provera Contraceptive Injection is given once in 3 months and its contraceptive effect lasts for 12 weeks.
The impact of Depo Provera Contraceptive Injection begins instantaneously on administration of the first dose which is usually within the first five days of the monthly period. Depo Provera Contraceptive Injection is known to be 99% safe and the chances of pregnancy in women using Depo Provera Contraceptive Injections are 1 in 100. Depo Provera Contraceptive Injection effectively averts the chances of pregnancy by inhibiting the activity of hormones called gonadotropins which are responsible for the release of the egg from the ovary during the cycle of ovulation.
Without the gonadotropins, the egg is not released and thus pregnancy cannot occur. Even if the egg is released from the ovary, Depo Provera Contraceptive Injections also alter the lining of the uterus which makes it difficult for the fertilized egg to attach to the uterus.
Depo Provera Shot is also used as intravenous therapy for the treatment of endometriosis, a medical condition in which the cells of the uterus develop outside the uterus. Medroxyprogesterone Acetate injections are also recommended for the effective treatment of pain and certain symptoms associated with various types of cancer such as metastatic uterine cancer, breast cancer, kidney cancer, and cancer of the endometrium.
Depo Provera shots can only be used for the treatment of the symptoms of these cancers but cannot be administered as a cure for the cancer. Depo Provera Contraceptive Injection cannot be used to prevent the transmission of sexually transmitted diseases. For these purpose, you should use a barrier-method of contraception such as latex male condoms.

Depo Provera Shot Dosage - How to Take Depo Provera Contraceptive Injection?

Depo Provera Contraceptive Injection should be administered only by a doctor.
Depo Provera Contraceptive Injection is taken on any of the first five days after the monthly period, when the chances of being pregnant are very low.
Depo Provera Shot can be given after these five days, once the doctor is certain that you are not pregnant. However, you will need additional contraception such as condoms for the first 7 days after the injection.
In case of breastfeeding mothers, Depo Provera Contraceptive Injection can be administered only after 6 weeks of childbirth to eliminate the risk of transmitting the drug to the nursing child through the breastmilk. If a woman decides to avoid breastfeeding after childbirth, she can take Depo Provera Contraceptive Injection 5 days after delivery.
Women who have had an abortion or miscarriage before the completion of 24 weeks of pregnancy can be administered Depo Provera Contraceptive Injection immediately and they will benefit from the contraceptive effect of the injection right away.  If Depo Provera Contraceptive Injection is administered 7 days after the miscarriage or abortion, you should use an additional method of contraception such as condoms for the first 7 days after the injection.
Depo Provera Shot are given once every 3 months (13 weeks) or once a week depending on your medical condition. Always stick to your regular schedule and do miss out any planned shots because it increases the risk of pregnancy. Depo Provera Contraceptive Injection are administered into the muscle or under the skin such as buttock, or into the thigh or tummy (abdomen).

Medroxyprogesterone Acetate Mechanism of Action – How Does Depo Provera Shot Work?

Depo Provera Contraceptive Injection is meant for the effective birth control in women. Depo Provera Shot contains Medroxyprogesterone Acetate as the active ingredient which is a synthetic version of the female hormone called progesterone.
Depo Provera Contraceptive Injection is used as long-term contraception i.e. a single shot of Depo Provera Contraceptive Injection is effective for about 12 weeks. Medroxyprogesterone Acetate is administered into muscles or skin of the buttocks or upper arm. After injecting Depo Provera Contraceptive Injection, a reserve of Medroxyprogesterone Acetate is created in the muscle, from where the drug is continuously discharged into the bloodstream for the next 12 weeks. 
Medroxyprogesterone Acetate averts the chances of pregnancy in women through three main mechanisms. Primarily, it inhibits the discharge of the eggs from the ovaries during the process of ovulation. It also alters the cervical mucus by increasing its thickness at the entrance of the womb, thus rendering it more challenging for the sperm to transverse from the vagina towards the womb. By preventing sperm access to the womb, Medroxyprogesterone Acetate inhibits the fertilization of any eggs which may be released from the ovary.
The hormone also modifies the properties of the womb lining (endometrium), making it less accessible for attachment by any fertilized eggs.

The contraceptive impact of Depo Provera Shot (Depo Provera CI 150mg) persists for three months. Patients are advised to discuss the advantages and associated risks related this method of contraception with your doctor before starting the course of Depo Provera Contraceptive Injection.
Women should pay special attention to the possibility of having children after discontinuing the injections. Women are known to become fertile once again, after the injections are discontinued. However, the time period for fertility to occur differs between patients. Usually, most women should begin ovulating 5 to 6 months after their last Depo Provera Contraceptive Injection, but you may be unable to become pregnant until 10 to 15 months after your last injection (or sometimes even longer).

Depo Provera Shot - Missed Dose

If you miss your regular dose of Depo Provera Contraceptive Injection, please consult your doctor. 

Storage Instructions for Depo Provera Shot (Depo Provera CI 150mg)

Store the pack of Depo Provera Contraceptive Injection at room temperature (20 – 25°C), protected from heat, moisture, and sunlight.
Retain the original packing of the medication and do not use Depo Provera Contraceptive Injection beyond its expiration date printed on the vial. Keep the pack of Depo Provera Contraceptive Injection away from the reach of children and pets. Do not discard Depo Provera Contraceptive Injection along with domestic waste or sewage.
Depo Provera Contraceptive Injection should be given using disposable needles for every use. Discard the needles in a puncture-proof container, which is kept away from the reach of children and pets. During the course of Depo Provera Contraceptive Injections, consult your doctor regularly for any queries. Consult your doctor or pharmacist about the correct method of disposal.

Warnings and Precautions to be taken when using Depo Provera Contraceptive Injection

Medical History
Before beginning the treatment with Depo Provera Shot, discuss your personal and family medical history with your doctor. Inform your doctor if you have unusual vaginal bleeding, breast cancer, liver disease, thrombophlebitis (inflammation of a vein with development of a blood clot), any blood-clotting disorders such as a heart attack or stroke, disease of the blood vessels in the brain, kidney disease, high blood pressure, congestive heart failure, migraine, headaches, diabetes, asthma, bone disease or a family history of osteoporosis, seizures, depression, an eating disorder, if you have ever had a breast lump, an abnormal mammogram, or bleeding from your nipples, or if you drink large amounts of alcohol or if you smoke.

Allergy
Please inform your doctor if you have an allergy or have had an allergic reaction in the past to Medroxyprogesterone Acetate or any inactive ingredient in Depo Provera Shot. Please tell your doctor if you have any other allergies.  
Surgery and Regular Medical Tests
If you plan to have surgery or any dental procedure, inform your doctor, anesthetist, or dentist about your course of Depo Provera Contraceptive Injection. In case of an emergency medical treatment, please inform the practitioner about your course of Depo Provera Contraceptive Injection and the details of your last dose.
Depo Provera Contraceptive Injection and the Risk of Osteoporosis
The administration of Depo Provera Contraceptive Injection over long periods of time is known to decrease the estrogen blood levels and is related to substantial irreversible loss of bone mineral density. Women should avoid using Depo Provera Shot for more than 2 years. Consult your doctor about your detailed risk of bone loss and osteoporosis.
Depo Provera Contraceptive Injection and Alcohol
Avoid or limit the consumption of alcohol during the treatment with Depo Provera Contraceptive Injection and consult your doctor for more information.
Depo Provera Contraceptive Injection – Driving and Other Activities
Depo Provera Contraceptive Injection may make you light-headed or impair your vision. Avoid activities such as driving, using machinery, or performing any activity that requires complete vigilance or perfect vision until you are sure about your safety.

Depo Provera Shot Interactions

Before beginning the oral therapy of Depo Provera Shot, please tell your doctor about all your present medications including prescription drugs, over the counter medications, mineral supplements, herbal products, and vitamins. Depo Provera Contraceptive Injection is known to have drug interactions with certain other medications. Please inform your doctor if you are taking any seizure medication or an oral, nasal, inhaled, or injectable steroid medicine.
Progestogens such as Medroxyprogesterone Acetate may increase the levels of selegiline and tizanidine in the blood and this could possibly increase the risk of their side effects.
Ulipristal (the active ingredient of the emergency contraceptive Ellaone and the medicine for fibroids Esmya) is known to decrease the efficacy of Depo Provera Shot. You should avoid taking Ellaone during the course of treatment with Depo-Provera injections and you should begin the course of treatment with Depo-Provera injections at least 12 days after you have discontinued the administration of Esmya.

Depo Provera Contraceptive Injection Contraindications

Depo Provera Contraceptive Injection are contraindicated in patients with a known hypersensitivity to Medroxyprogesterone Acetate or any inactive ingredient present in Depo Provera Shot.

Side Effects of Depo Provera Shot

The following side effects have been reported during the course of treatment with Depo Provera Shot:

• Cardiovascular System- chest pain, rapid breathing,
• Central Nervous System- dizziness, headache, nervousness, depression, confusion
• Eye and ENT- problems with vision, speech, or balance, sudden cough, wheezing, rapid breathing, coughing up blood
• Gastrointestinal System- abdominal pain or discomfort, upper stomach pain, dark urine, clay-colored stools, jaundice
• Genitourinary System- unpredictable menstrual bleeding, spotting, increase or decrease in amount of bleeding, decreased libido, breast tenderness,
• Musculoskeletal System- decrease in bone mineral density, increased risk of osteoporosis, swelling in your hands/ankles/feet
• Hypersensitivity- hives, difficulty breathing, swelling of your face/lips/tongue/throat, pain/swelling/warmth/redness in one or both legs
• General- amenorrhea, weakness or fatigue, weight gain, weight loss, acne, change in appetite, excessive growth of facial and body hair, hair loss, itching, hot flash,

Inform your doctor immediately if you experience any of these side effects. This is not an exhaustive list of all the potential side effects of Depo Provera Shot. If you develop any other medical conditions during the course of treatment with Medroxyprogesterone Acetate injection. 

Depo Provera Contraceptive Injection during Pregnancy and Breastfeeding

Depo Provera Contraceptive Injection should not be administered in pregnant women because it is intended for contraceptive purposes. Depo Provera Shot should be administered only once it is confirmed that the patient is not pregnant.
Medroxyprogesterone Acetate is secreted into breastmilk. However, it is still not known if Medroxyprogesterone Acetate is harmful to the nursing baby. Nursing mothers should be careful if they are breastfeeding an infant during the course of Depo Provera Contraceptive Injection.
Depo Provera Contraceptive Injection can be administered only after 6 weeks of childbirth to eliminate the risk of transmitting the drug to the nursing child through the breastmilk.

Buy Depo-Provera Injection Online From Only $19 per Vial

You can buy Depo-Provera Injection online from Everest Online Pharmacy at a cheap price. Depo-Provera 150 mg Contraceptive Injection, manufactured by Pfizer, Belgium is supplied in a box containing a 1 ml vial of 150 mg strength . The 150 mg injections cost only $19 per unit when you place an order for 15 vials.

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