Augmentin Tablets

Augmentin Tablets (Amoxicillin And Clavulanate Potassium Tablets)- Product Information

Augmentin tablets belongs to a class of drugs knowns as penicillin antibiotics. Augmentin tablets contains a combination of two active ingredients - amoxicillin and clavulanate potassium.
Augmentin tablets are prescribed as oral therapy in adults and children for the treatment and prevention of various bacterial infections such as lower respiratory tract infections (acute exacerbations of chronic bronchitis, lobar and broncho-pneumonia), genito-urinary tract infections (cystitis, urethritis, pyelonephritis, female genital infections, yeast infections), skin and soft tissue infections, bone and joint infections (osteomyelitis), other infections (ear infections, dental infections, septic abortion, puerperal sepsis, intra-abdominal sepsis, septicaemia, peritonitis, post-surgical infections). In our online pharmacy, Augmentin tablets are available in the strength of 375 mg, 625 mg, and 1000 mg of amoxicillin and clavulanate potassium.

Drug Name

Augmentin tablets.
Other generic brand names for Augmentin include Amoxiclav, Augmentin Duo Forte, Clamoxyl Duo Forte, Clavam, Clavycillin, Curam Duo, GA-Amclav, Moxiclav Duo Forte, Pharmacor Amoxiclav.

Manufacturer of Augmentin Tablets

Augmentin tablets, available in our online pharmacy are manufactured by GlaxoSmithKline (GSK India).
(Website: www.gsk.com)

Active Pharmaceutical Ingredient

Augmentin tablets contain a combination of two active ingredients, amoxicillin and clavulanate potassium.
Our online pharmacy has stocks of three strengths of Augmentin tablets- 375 mg, 625 mg, and 1000 mg. Augmentin 375 mg contains a combination of 250 mg Amoxicillin & 125 mg Potassium Clavulanate. Augmentin 625 mg contains a combination of 500 mg Amoxicillin & 125 mg Potassium Clavulanate. Augmentin 1000 mg contains a combination of 875 mg Amoxicillin & 125 mg Potassium Clavulanate. The inactive ingredients present in Augmentin pills are colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, sodium starch glycolate, and titanium dioxide.

What are Augmentin Tablets Used For?

Augmentin tablets, manufactured by GlaxoSmithKline, contains a combination of two active ingredients, amoxicillin and clavulanate potassium. Augmentin tablets are penicillin antibiotics which are used to treat and prevent bacterial infections.
Augmentin tablets are typically administered as oral therapy for the treatment and prevention of various bacterial infections such as lower respiratory tract infections (bronchitis, pneumonia, strep throat) which are caused by Haemophilus influenzae and Moraxella catarrhalis, acute bacterial otitis media (ear infection) which are caused by H. influenzae and M. catarrhalis, sinusitis which are caused by H. influenza and M. catarrhalis, skin and skin structure infections (cellulitis, animal bites, tooth infection such as severe dental abscess with spreading cellulitis) which are caused by Staphylococcus aureus, Escherichia coli, and Klebsiella species, urinary tract infections (cystitis, urinary infection, pyelonephritis gonnorhea) which are caused by E. coli, Klebsiella species, and Enterobacter species, and bone and joint infections (osteomyelitis). Treatment with Augmentin tablets is also recommended in female patients who have developed infections due to difficulties during pregnancy, childbirth, or abortion (puerperal sepsis and septic abortion). Augmentin tablets should not be unnecessarily administered because it can drastically decrease the efficacy of the antibiotic in the patient. Augmentin tablets should be administered in only those patients who display clear symptoms of these specific bacterial infections. Augmentin tablets cannot be used for the treatment of viral infections such as common cold and flu.

Augmentin Dosage - How to Take Augmentin Tablets?

You should use Augmentin tablets exactly as recommended by your doctor. Your doctor may suggest a dosage of Augmentin tablets depending on the type of bacteria, the severity and site of your bacterial infection, age, body weight, renal function, other medical conditions, and current medications.
Augmentin tablets should be taken with a glass of water, at the start of a meal to avoid indigestion problems. Try to maintain a regular schedule for the medication such that you take Augmentin tablets at the same time every day, to get the maximum benefit of the medication. Antibiotics are most effective when its concentration is maintained at a constant level in the body. Make sure Augmentin tablets are administered at definite intervals for effective results. If you’re administered a high dosage of Augmentin tablets, make sure you keep your body hydrated by consuming a sufficient amount of oral fluids.
The recommended daily dosage of Augmentin tablets for most bacterial infections is 375 mg every 8 hours, or 625 mg every 12 hours. Your doctor may alter the dosage of Augmentin tablets and dosage period depending on the type and severity of your infection and your response to treatment. However, the treatment period with Augmentin tablets should not exceed 14 days. The suggested dose for severe and respiratory tract infections is 1000 mg Augmentin tablet every 12 hours or 625 mg Augmentin tablet every 8 hours administered orally. In adults, the maximum recommended daily dosage is 1500 mg amoxicillin/375 mg clavulanic acid.

For most bacterial infections, children weighing more than 40 kg are recommended a maximum recommended daily dosage of 2400 mg amoxicillin/600 mg clavulanic acid. Children weighing less than 25 kg should not be administered Augmentin tablets.
It is imperative that you complete the recommended course of treatment with Augmentin tablets even if you feel better or if it seems the infection has cleared up. Discontinuing the treatment course prematurely or skipping doses will escalate the risk of the infection relapse and the bacteria will grow resistant to the Augmentin antibiotic treatment.

Augmentin Mechanism of Action – How Does Amoxicillin and Clavulanic Acid Work?

Augmentin belongs to the class of penicillin antibiotics, which contains a combination of two active ingredients, amoxicillin and clavulanate potassium. Amoxicillin is a semi-synthetic penicillin (also known as a beta-lactam antibiotic) that prevents the activity of enzymes called penicillin-binding proteins (PBPs). These enzymes are essential for the synthesis of bacterial peptidoglycan, which is a fundamental structural element present in the bacterial cell wall. Effective suppression of bacterial peptidoglycan synthesis results in the formation of a fragile cell wall which is susceptible to cell lysis and eventually cell death. However, Amoxicillin is prone to destruction by the activity of beta-lactamases family of enzymes. The beta-lactamase enzymes are synthesized by resistant bacteria, which renders amoxicillin ineffective against the bacteria which produce them. Clavulanic acid is a beta-lactam and has a structure which is similar to penicillin. Clavulanic acid is capable of hindering the activity of certain beta-lactamase enzymes which further prevents these enzymes from inhibiting amoxicillin. Clavulanic acid on its own is not capable of producing a therapeutic antibacterial effect.

Augmentin Tablets - Missed Dose

If you miss your regular dose of Augmentin tablets, take it as soon as you remember. You can continue your regular schedule the next day. If you remember the missed Augmentin tablets the next day, take your regular dose and skip the missed dose.
Do not take a double dose to compensate the missed dose of Augmentin tablets.

Storage Instructions for Augmentin Tablets

Store the pack of Augmentin tablets at room temperature (20 – 25°C), protected from heat, moisture, and sunlight. Retain the original packing of the medication and do not consume Augmentin tablets beyond its expiration date printed on the blister pack.
Keep the pack of Augmentin tablets away from the reach of children and pets. Do not discard Augmentin tablets along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.

Warnings and Precautions to be taken when using Augmentin Tablets

Medical History
Before beginning the treatment with Augmentin tablets, discuss your personal and family medical history with your doctor. Inform your doctor if you have kidney disease, liver disease, phenylketonuria, mononucleosis, glandular fever, hemodialysis, problems in passing urine, or any atopic allergies.
Allergy
Please inform your doctor if you have an allergy or have had an allergic reaction in the past to amoxicillin, clavulanate potassium, penicillin, cephalosporin antibiotics, or any inactive ingredient in Augmentin tablets.
Live Vaccination, Surgery and Regular Medical Tests
If you plan to have live vaccinations, surgery or any dental procedure, inform your doctor or dentists about your course of Augmentin tablets. In case of an emergency medical treatment, please inform the practitioner about your course of Augmentin tablets and the details of your last dose.
Augmentin Tablets and Alcohol
There are no known interactions of Augmentin tablets with alcohol.
Augmentin Tablets – Driving and Other Activities
Augmentin tablets may make you light-headed or impair your vision. Avoid activities such as driving, using machinery, or performing any activity that requires complete vigilance or perfect vision until you are sure about your safety.
Augmentin and Birth-control,
Hormonal birth control methods such as birth control pills may not be efficacious during the course of Augmentin tablets. To prevent pregnancy, use barrier methods of birth control such as condoms, diaphragms or spermicide.

Augmentin Interactions

Before beginning the oral therapy of Augmentin tablets, please inform your doctor of all your current medications including prescription drugs, over the counter medications, mineral supplements, herbal products, and vitamins.
Augmentin is known to have drug interactions with warfarin (anticoagulant), Probenecid, Allopurinol, Mycophenolate Mofetil, and Methotrexate, which may increase the risk of side effects caused by Augmentin.

Augmentin Contraindications

The treatment with Augmentin tablets is contraindicated in patients who are allergic to amoxicillin, clavulanate potassium or any inactive ingredients present in Augmentin tablets. Augmentin Tablets (Amoxicillin and Clavulanate potassium) are also contraindicated in patients with a medical history of allergic responses to any cephalosporin antibiotics or penicillin antibiotics such as amoxicillin, ampicillin, dicloxacillin. Augmentin tablets are also contraindicated in patients with a medical history of cholestatic jaundice/hepatic dysfunction related to Augmentin administration. 

Side Effects of Augmentin Tablets

The following side effects have been reported during the course of treatment with Augmentin tablets:

• Central Nervous System- agitation, confusion, unusual thoughts or behaviour, seizure, headache.
• Gastrointestinal System- oral thrush-white, furry, sore tongue and mouth, diarrhoea, nausea, vomiting or indigestion, upper stomach pain.
• Genitourinary System- vaginal thrush-sore and itchy vagina and/or discharge, dark coloured urine.
• Hypersensitivity- fever, itching, burning skin, severe chills, sore throat, rash, mouth ulcers, difficulty breathing, swelling of your face/ lips/tongue/throat.
• General- loss of appetite, general feeling of uneasiness, yellowing of the skin and eyes (jaundice), easy bruising, bleeding, numbness.

Inform your doctor immediately if you experience any of these side effects. This is not a comprehensive list of all the possible side effects of Augmentin. If you develop any other medical conditions during the course of treatment with Augmentin tablets, please consult your doctor immediately.

Augmentin Tablets during Pregnancy and Breastfeeding

Augmentin tablets are Pregnancy Category B medication. The administration of Augmentin tablets is not known to cause any defects in the growing fetus. However, the risk of administering Augmentin tablets to pregnant women should be discussed with the doctor.
Amoxicillin and clavulanate potassium are known to be secreted through breast milk. Women planning a pregnancy or nursing an infant during the course of Augmentin tablets should consult their doctor before they do so.

Buy Augmentin 375 mg, 625 mg and 1000 mg Pills Online From Only $1 per Pill

You can buy Amoxicillin and Clavulanate Potassium tablets online from Everest Online Pharmacy at a cheap price. Augmentin 375 mg, 625 mg and 1000 mg pills, manufactured by GlaxoSmithkline, India are supplied in a blister strip of 10 tablets. The 375 mg tablets cost only $1 per unit when you place an order for 300 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith. It is without a warrant of any kind, expressed or implied.

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