Atorvastatin Calcium Tablets

Atorvastatin Calcium Tablets (Lipvas 10 mg 20 mg and 40 mg) - Product Information

Atorvastatin Calcium (Lipvas 10 mg 20 mg and 40 mg Tablets) is used together with a proper diet to lower cholesterol and triglyceride (fats) levels in the blood. This medicine may help prevent medical problems (eg, chest pain, heart attack, or stroke) that are caused by fats clogging the blood vessels. It may also be used to prevent certain types of heart and blood vessel problems in patients with risk factors for heart problems.
We also have in stock Amlopres Tablets (Generic Amlodipine Besylate) which is used for the treatment of high blood pressure and chest pain in adults and children who are at least 6 years old.

Name of the Drug

Lipvas Tablets.

Manufacturer of Lipvas Tablets

Cipla Limited, India  
Website: www.cipla.com

Active Pharmaceutical Ingredient

The active ingredient present in Lipvas tablets is Atorvastatin Calcium. Each film-coated Lipvas tablet contains Atorvastatin Calcium equivalent to 10 mg 20 mg or 40 mg of Atorvastatin.

Uses of Lipvas Tablets

Atorvastatin calcium tablets are a prescription medicine that lowers cholesterol in your blood. It lowers the LDL-C ("bad" cholesterol) and triglycerides in your blood. It can raise your HDL-C ("good" cholesterol) as well. Atorvastatin calcium tablets are for adults and children over 10 whose cholesterol does not come down enough with exercise and a low-fat diet alone.
Atorvastatin calcium tablets can lower the risk for heart attack, stroke, certain types of heart surgery, and chest pain in patients who have heart disease or risk factors for heart disease such as:

• age, smoking, high blood pressure, low HDL-C, heart disease in the family.
• Atorvastatin calcium tablets can lower the risk for heart attack or stroke in patients with diabetes and risk factors such as: eye problems, kidney problems, smoking, or high blood pressure.
• Atorvastatin calcium tablets start to work in about 2 weeks.

Atorvastatin Calcium Tablets (Lipvas 10 mg 20 mg and 40 mg) - Dosage

Generic Atorvastatin Calcium tablets should be administered exactly as suggested by your doctor. Your doctor may recommend a dosage of Lipvas tablets depending on your age, medical requirement, body weight, other medical conditions, and current medications.
Dose range: 10 to 80 mg once daily
Recommended start dose: 10 or 20 mg once daily
Patients requiring large LDL-C reduction (greater than 45%) may start at 40 mg once daily.
Pediatric starting dose: 10 mg once daily; maximum recommended dose: 20 mg once daily.
Lipvas tablets work effectively if the amount of Atorvastatin is maintained at a constant level in the body. You should be systematic about the daily schedule for the medication such that you take tablets at about the same time every day, to get the maximum benefit of the medication. Continue taking Atorvastatin Calcium tablets without missing any doses for the recommended treatment period and do not stop the treatment suddenly even if you feel better.
Please consult your doctor for exact dosing instructions. tablets (Generic Atorvastatin Calcium tablets) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Missed Dose

If you forget to take your regular Lipvas tablet dose on time, take it whenever you remember.
If you remember the next day, skip the missed dose and take your scheduled dose. Do not take a double dose to compensate the missed dose.

Atorvastatin Calcium Mechanism of Action

Atorvastatin is a selective, competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMGCoA) reductase, the rate-limiting enzyme that converts HMG-CoA to mevalonate, a precursor of sterols, including cholesterol. Atorvastatin reduces low density lipoprotein (LDL) production and the number of LDL particles. Triglycerides (TG) and cholesterol in the liver are incorporated into very low density lipoprotein (VLDL) and released into the plasma for delivery to peripheral tissues. LDL is formed from VLDL and is catabolized primarily through the high-affinity LDL receptor.
In animal models, atorvastatin lowers plasma cholesterol and lipoprotein levels by inhibiting HMGCoA reductase and cholesterol synthesis in the liver and by increasing the number of hepatic LDL receptors on the cell surface to enhance uptake and catabolism of LDL; atorvastatin also reduces LDL production and the number of LDL particles. Atorvastatin reduces LDL-C in some patients with homozygous familial hypercholesterolemia (HoFH), a population that rarely responds to other lipid lowering medication(s).

Storage Instructions for Lipvas 10 mg 20 mg and 40 mg Tablets

Store Lipvas 10 mg 20 mg and 40 mg tablets at controlled room temperature (20°C to 25°C),protected from heat, moisture, and sunlight. Excursions are permitted from 15°C to 30°C.
Retain the original packing of the medication and do not consume past its expiration date printed on the blister pack. Keep the pack of away from the reach of children and pets. Do not dispose Atorvastatin Calcium tablets along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.

Contraindications

Lipvas tablets are contraindicated in patients with a hypersensitivity to Atorvastatin Calcium or any inactive ingredient present in tablets. Lipvas tablets are contraindicated in the following cases:
Active liver disease, which may include unexplained persistent elevations in hepatic transaminase levels
Women who are pregnant or may become pregnant and in women of child-bearing potential not using appropriate contraceptive measures.
Nursing mothers

Overdose

There is no specific treatment available for Lipvas overdosage. In the event of an overdose, the patient should be treated symptomatically, and supportive measures instituted as required. Due to extensive drug binding to plasma proteins, hemodialysis is not expected to significantly enhance Atorvastatin clearance.

Warnings and Precautions

Skeletal muscle effects (e.g., myopathy and rhabdomyolysis):
Risks increase when higher doses are used concomitantly with cyclosporine and strong CYP3A4 inhibitors (e.g., clarithromycin, itraconazole, human immunodeficiency virus (HIV) or hepatitis C virus (HCV) protease inhibitors). Predisposing factors include advanced age (greater than 65), uncontrolled hypothyroidism, and renal impairment. Rare cases of rhabdomyolysis with acute renal failure secondary to myoglobinuria have been reported. Advise patients to promptly report to their physician unexplained and/or persistent muscle pain, tenderness, or weakness. Lipvas therapy should be discontinued if myopathy is diagnosed or suspected.
Liver enzyme abnormalities:
Persistent elevations in hepatic transaminases can occur. Check liver enzyme tests before initiating therapy and as clinically indicated thereafter
Hemorrhagic Stroke:
A higher incidence of hemorrhagic stroke was seen in patients without CHD but with stroke or TIA within the previous 6 months in the Atorvastatin 80 mg group vs. placebo

Side Effects of Atorvastatin Calcium Tablets (Lipvas 10 mg 20 mg and 40 mg)

The most commonly reported side effects with an incidence rate of 2% or more in patients treated with Atorvastatin Calcium Tablets (Lipvas 10 mg 20 mg and 40 mg) in placebo-controlled trials regardless of causality were: nasopharyngitis, arthralgia, diarrhea, pain in extremity, urinary tract infection, Dyspepsia, Nausea, Musculoskeletal pain, Muscle Spasms, Myalgia, Insomnia and Pharyngolaryngeal pain.

Atorvastatin Calcium During Pregnancy and Breastfeeding

Atorvastatin Calcium has been classified by the US FDA as Pregnancy Category X.
Lipvas is contraindicated in women who are or may become pregnant since safety in pregnant women has not been established and there is no apparent benefit of lipid lowering drugs during pregnancy. Because HMG-CoA reductase inhibitors decrease cholesterol synthesis and possibly the synthesis of other biologically active substances derived from cholesterol, atorvastatin may cause fetal harm when administered to a pregnant woman.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.
Lipvas tablets use is contraindicated during breastfeeding. There is no available information on the effects of the drug on the breastfed infant or the effects of the drug on milk production. It is not known whether Atorvastatin is present in human milk, but it has been shown that another drug in this class passes into human milk and Atorvastatin is present in rat milk.
Do not use this medication without telling your doctor if you are breast-feeding a baby.

Buy Atorvastatin Calcium tablets Online From Only $0.19 per Pill

You can buy Atorvastatin Calcium tablets online from Everest Online Pharmacy at a cheap price. Lipvas 10 mg 20 mg and 40 mg pills, manufactured by Cipla Limited, India, are supplied in a blister strip of 10 tablets. Lipvas 10 mg tablets cost only $0.19 per unit when you place an order for 360 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith. It is without a warrant of any kind, expressed or implied.

Shipping Restriction