Arpizol Tablets

Arpizol (Generic Aripiprazole Tablets) - Product Information

Aripiprazole Tablets (Arpizol) is used alone or together with other medicines to treat mental conditions such as bipolar I disorder (manic-depressive illness), major depressive disorder, and schizophrenia.
It is also used in children to treat irritability associated with autistic disorder and Tourette syndrome.
In our online pharmacy, Arpizol tablets are available in the strength of 10 mg, 15 mg, 20 mg, and 30 mg of Aripiprazole.
We also have in stock Imipramine Hydrochloride Tablets (Antidep) which are used to treat various symptoms of depression.

Name of the Drug

Arpizol tablets. Arpizol tablets are also available under different brand names such as Apicord, Arena, Aria, Aridus, Arilan, Arip MT, Aripat-MD, Aripicon, Aripra, Aripra, MT, Arive, Arize, Arol, Arole, Arpicin, Asprito, Arza, Arzu, Biliff, Elrip, Pipra A, Real One, Rizotal, and Schizopra. Aripiprazole tablets are also known as Generic Aripiprazole tablets.

Sun Pharmaceutical Industries Limited, India

Manufacturer of Arpizol Tablets

Sun Pharmaceutical Industries Limited, India  
Website: sunpharma.com

Active Pharmaceutical Ingredient

The active ingredient present in Arpizol tablets is Aripiprazole. Each Arpizol tablet contains either 10 mg, 15 mg, 20 mg, or 30 mg of Aripiprazole.

Uses of Arpizol Tablets

Aripiprazole (Arpizol tablets by Sun Pharma) is also used to treat:
Tourette's disorder or symptoms of autistic disorder (irritability, aggression, mood swings, temper tantrums, and self-injury) in children 6 years or older
bipolar I disorder (manic depression) in adults and children at least 10 years old, either in combination with a mood stabilizer medicine or alone
major depressive disorder in adults in combination with an antidepressant.

Arpizol Dosage - How to Take Aripiprazole Tablets?

Generic Aripiprazole tablets should be administered exactly as suggested by your doctor. Your doctor may recommend a dosage of Arpizol tablets depending on your age, medical requirement, body weight, other medical conditions, and current medications.
Aripiprazole tablets should be swallowed with a glass of water. Aripiprazole tablets can be taken with or without food. You should be systematic about the daily schedule for the medication such that you take Arpizol tablets at the same time every day, to get the maximum benefit of the medication.
Aripiprazole tablets is usually administered as short-term treatment for period of six weeks unless your doctor has advised you differently. Your doctor may recommend a low starting dose and gradually increase your dosage depending upon the efficacy of the drug for your condition and to reduce the risk of side effects.
Schizophrenia (Adults)
Dose Selection: The recommended starting and target dose for Arpizol tablets is 10 mg/day or 15 mg/day administered on a once-a-day schedule without regard to meals.
Schizophrenia (Adolescents)
Dose Selection: The recommended target dose of Arpizol tablets is 10 mg/day.The starting daily dose of the tablet formulation in these patients was 2 mg, which was titrated to 5 mg after 2 days and to the target dose of 10 mg after 2 additional days.
Bipolar I Disorder (Adults)
Dose Selection: The recommended starting and target dose is 15 mg given once daily as monotherapy or as adjunctive therapy with lithium or valproate. Aripiprazole tablets may be given without regard to meals.
Bipolar I Disorder (Pediatric Patients)
Dose Selection: The efficacy of Aripiprazole tablets has been established in the treatment of pediatric patients 10 to 17 years of age with bipolar I disorder at doses of 10 mg/day or 30 mg/day. The recommended target dose of Aripiprazole tablets is 10 mg/day, as monotherapy or as adjunctive therapy with lithium or valproate.
The starting daily dose of the tablet formulation in these patients was 2 mg/day, which was titrated to 5 mg/day after 2 days and to the target dose of 10 mg/day after 2 additional days.
Continue taking Aripiprazole tablets for the recommended treatment period without missing any doses. Do not stop the treatment temporarily even if you feel that your symptoms have cleared because Arpizol tablets can only help to control your symptoms but it does not cure the medical condition.
Treatment with Aripiprazole tablets may show noticeable results in about six weeks after the start of treatment.

Missed Dose

If you miss your regular dose of Aripiprazole tablets, take it as soon as you remember. You can continue your regular schedule the next day.
If you remember the missed Aripiprazole tablets the next day, take your regular dose and skip the missed dose. Do not take a double dose to compensate the missed dose of Aripiprazole tablets.

Aripiprazole Mechanism of Action – How Does Arpizol Work?

Aripiprazole is an antipsychotic medication which is used by adult and adolescent patients suffering from psychotic conditions such as schizophrenia, bipolar disorder, and clinical depression. Aripiprazole tablets belongs to a class of drugs known as atypical antipsychotics.
Aripiprazole works primarily by modulating both dopamine and serotonin signaling pathways, making it an antipsychotic with a unique mechanism of action. It is a partial agonist at the dopamine D2 and D3 receptors and also a partial agonist at the serotonin 5-HT1A receptors, while acting as an antagonist at the 5-HT2A receptors.

Storage Instructions for Arpizol Tablets

Store the pack of Aripiprazole tablets at controlled room temperature (20°C to 25°C), protected from heat, moisture, and sunlight. Excursions permitted to 15°C to 30°C. Retain the original packing of the medication and do not consume Aripiprazole tablets (Arpizol) beyond its expiration date printed on the blister pack.
Keep the pack of Generic Aripiprazole tablets away from the reach of children and pets. Do not discard Aripiprazole tablets along with domestic waste or sewage.
Consult your doctor or pharmacist about the correct method of disposal.

Contraindications

Generic Aripiprazole tablets are contraindicated in patients with a known hypersensitivity to Aripiprazole or any inactive ingredient present in Arpizol tablets.

Overdose

Clinical Symptoms commonly associated with Aripiprazole (Arpizol tablets) overdose include gastrointestinal disturbance, somnolence, orthostatic hypotension, and extrapyramidal symptoms, as well as cardiac disturbances, most commonly tachycardia and QT interval (QTc) prolongation.

Warnings and Precautions

Use in Elderly Patients with Dementia-Related Psychosis
Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Aripiprazole is not approved for the treatment of patients with dementia-related psychosis
Clinical Worsening of Depression and Suicide Risk:
Patients with major depressive disorder (MDD), both adult and pediatric, may experience worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or unusual changes in behavior, whether or not they are taking antidepressant medications, and this risk may persist until significant remission occurs.
Neuroleptic Malignant Syndrome (NMS)
A potentially fatal symptom complex sometimes referred to as Neuroleptic Malignant Syndrome (NMS) may occur with administration of antipsychotic drugs, including aripiprazole. Rare cases of NMS occurred during aripiprazole treatment in the worldwide clinical database. Clinical manifestations of NMS are hyperpyrexia, muscle rigidity, altered mental status, and evidence of autonomic instability (irregular pulse or blood pressure, tachycardia, diaphoresis, and cardiac dysrhythmia).
Tardive Dyskinesia
A syndrome of potentially irreversible, involuntary, dyskinetic movements may develop in patients treated with antipsychotic drugs. Although the prevalence of the syndrome appears to be highest among the elderly, especially elderly women, it is impossible to rely upon prevalence estimates to predict, at the inception of antipsychotic treatment, which patients are likely to develop the syndrome.
Hyperglycemia and Diabetes Mellitus
Hyperglycemia, in some cases extreme and associated with ketoacidosis or hyperosmolar coma or death, has been reported in patients treated with atypical antipsychotics. There have been few reports of hyperglycemia in patients treated with Aripiprazole
Orthostatic Hypotension
Aripiprazole may cause orthostatic hypotension, perhaps due to its a1-adrenergic receptor antagonism. The incidence of orthostatic hypotension-associated events from short-term, placebo-controlled trials of adult patients on oral Aripiprazole
Leukopenia, Neutropenia, and Agranulocytosis
Class Effect: In clinical trial and/or postmarketing experience, events of leukopenia/neutropenia have been reported temporally related to antipsychotic agents, including Aripiprazole. Agranulocytosis has also been reported.
Seizures/Convulsions
In short-term, placebo-controlled trials, seizures/convulsions occurred in 0.1% (3/2467) of adult patients treated with oral aripiprazole, in 0.2% (1/611) of pediatric patients (6 to 17 years) treated with oral Aripiprazole.
Potential for Cognitive and Motor Impairment
Aripiprazole tablets, like other antipsychotics, may have the potential to impair judgment, thinking, or motor skills.
Body Temperature Regulation
Disruption of the body's ability to reduce core body temperature has been attributed to antipsychotic agents. Appropriate care is advised when prescribing Aripiprazole for patients who will be experiencing conditions which may contribute to an elevation in core body temperature
Dysphagia
Esophageal dysmotility and aspiration have been associated with antipsychotic drug use, including Aripiprazole tablets.
Aripiprazole Tablets and Alcohol
Avoid or limit the consumption of alcohol during the treatment with Generic Aripiprazole tablets (Arpizol tablets) because the combination of alcohol along with Aripiprazole tablets may make you dizzy, drowsy or light-headed.
Aripiprazole Tablets - Driving and Other Activities
Aripiprazole tablets may make you light-headed or impair your vision.
Avoid activities such as driving, using machinery, or performing any activity that requires complete vigilance or perfect vision until you are sure about your safety.
Surgery and Regular Medical Tests
If you plan to have surgery or any dental procedure, inform your doctor, anesthetist, or dentist about your course of Aripiprazole tablets. In case of an emergency medical treatment, please inform the practitioner about your course of Aripiprazole tablets and the details of your last dose.

Side Effects of Arpizol Tablets

The following side effects have been reported during the course of treatment with Arpizol tablets (Generic Aripiprazole tablets):

• Cardiovascular System- chest pain, fast/slow/irregular heartbeat
• Central Nervous System- abnormal dreams/thinking, dizziness, drowsiness, headache, light-headedness, insomnia, confusion, fainting, involuntary movements of the tongue/ face/mouth/jaw/arms/legs/back, loss of coordination, mental or mood changes, anxiety, depression, hostility, seizures, severe restlessness, suicidal thoughts or attempts
• Eye and ENT-blurred vision, vision or speech changes, stuffy nose
• Gastrointestinal System- constipation, increased saliva production, nausea, indigestion, vomiting, heartburn, jaundice
• Genitourinary System- increased urination, loss of control over urination
• Musculoskeletal System- muscle tremor, jerking, muscle stiffness, one-sided weakness, tightening of the neck muscles
• Hypersensitivity- rash, hives, high fever, swelling of face/hands/legs/lips/tongue/throat, tightness in chest, shortness of breath, difficulty in swallowing
• General- weight gain, increased sweating; increased thirst and appetite, inability to walk

Inform your doctor immediately if you experience any of these side effects. This is not an exhaustive list of all the potential side effects of Arpizol tablets (Generic Aripiprazole tablets). If you develop any other medical conditions during the course of treatment with Aripiprazole.

Aripiprazole Tablets during Pregnancy and Breastfeeding

Aripiprazole has been classified by the US FDA as Pregnancy Category C medication.
Neonates exposed to antipsychotic drugs, including Aripiprazole, during the third trimester of pregnancy are at risk for extrapyramidal and/or withdrawal symptoms following delivery. Overall available data from published epidemiologic studies of pregnant women exposed to Aripiprazole have not established a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes.
In animal studies, aripiprazole demonstrated developmental toxicity, including possible teratogenic effects in rats and rabbits.
Aripiprazole was excreted in milk of rats during lactation. It is still not known if whether Aripiprazole or its metabolites are excreted in human milk. It is recommended that women receiving Aripiprazole should not breast-feed.
For these reasons, pregnant women and breast feeding mothers should check with their doctor and understand its therapeutic benefits and associated risks before beginning the treatment with Aripiprazole tablets.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.

Buy Aripiprazole 5 mg, 10 mg, 15 mg, 20 mg and 30 mg Tablets Online From Only $0.53 per Pill

You can buy Aripiprazole tablets online from Everest Online Pharmacy at a cheap price.
Arpizol tablets manufactured by Sun Pharmaceutical Industries Limited, India are available in pills of 5 mg, 10 mg, 15 mg, 20 mg and 30 mg and supplied in a blister strip of 10 tablets.
The 5 mg tablets cost only $0.53 per unit when you place an order for 200 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith, it is without a warrant of any kind, expressed or implied.

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