Aldactone Tablets

Spironolactone Tablets (Aldactone Tablets) - Product Information

Spironolactone is a potassium-sparing diuretic (water pill) which are orally administered for the treatment of high blood pressure and also fluid retention in patients with medical conditions such as congestive heart failure, cirrhosis of the liver, Polycystic Ovary Syndrome (PCOS), hypokalemia (low potassium levels in blood), and nephrotic syndrome (kidney disorder).
Aldactone tablets prevent fluid retention by inhibiting the absorption of excessive salt and retain the potassium levels in blood. Spironolactone tablets of strengths 25 mg, 50 mg, and 100 mg are available at our online pharmacy.
We also have in stock Amlodipine Besylate tablets (Amlopres) which are prescribed as oral therapy for the treatment of high blood pressure and chest pain in adults and children who are at least 6 years old.

Name of the Drug

Spironolactone is available under the name of Aldactone tablets at our online pharmacy.

Manufacturer of Spironolactone Tablets

Aldactone tablets are manufactured by RPG Life Science Ltd.  
Website: www.rpglifesciences.com

Active Pharmaceutical Ingredient

The active ingredient present in Aldactone tablets is Spironolactone.
Each oral Aldactone tablet contains either 25, 50, or 100 mg of Spironolactone. The inactive ingredients in Spironolactone tablets are calcium sulfate, corn starch, flavor, hypromellose, iron oxide, magnesium stearate, polyethylene glycol, povidone, and titanium dioxide.

What are Aldactone Tablets Used For?

Spironolactone tablets are used for the treatment of high blood pressure which helps in prevention of adverse medical conditions such as strokes, heart attacks and kidney disorders. Keep in mind that Spironolactone tablets can only help regulate high blood pressure and not cure it.
Spironolactone tablets also prevent fluid retention, improve breathing difficulties and weight conditions which develop during congestive heart failure, liver cirrhosis and kidney disorders (nephrotic syndrome).
Spironolactone tablets are also known as potassium-sparing diuretic (water pill) because they are also used for the treatment of low potassium levels in the body (hypokalemia) due to the presence of increased aldosterone hormone (hyperaldosteronism).
Spironolactone for PCOS:
Aldactone tablets are also prescribed for Polycystic Ovary Syndrome (PCOS) patients who have excessive hair growth (hirsutism). In women with PCOS, Spironolactone tablets also reduce male-pattern hair growth (hirsutism), hair loss, and acne.
Aldactone for Acne:
Spironolactone (Aldactone tablets) are also used to treat localized skin inflammation (acne) due to the occurrence of oil glands at the base of hair follicles.

Drug Dosage

Generic Spironolactone tablets (Aldactone) are to be orally administered along with food or a glass of milk to avoid digestion problems. Consume the Aldactone tablets regularly and at the same time everyday to get the maximum therapeutic benefit of the medication.
It is preferably recommended to take Aldactone tablets early in the day (i.e. before 6 p.m.) to avoid the trouble of waking up during the night to pass urine.
Take the dosage of Spironolactone tablets exactly as prescribed by your doctor. The usual daily dosage of Spironolactone for acne treatment is 50 - 100 mg. Your doctor will prescribe the dosage of Spironolactone tablets depending on your medical condition and your response to treatment. Do not alter the dosage or the dosage period without consulting your doctor.
Also, do not discontinue the course of Spironolactone tablets without informing your doctor because abrupt termination of Aldactone tablets may result in adverse conditions.

Spironolactone Tablets - Missed Dose

If you forget to take a dose of Spironolactone tablets on the same day, take it as soon as you remember. However, if you remember the next day, skip the missed dose and take your scheduled dose. Do not take a double dose to compensate the missed dose.

Aldactone Mechanism of Action - How Does Spironolactone Work?

Aldosterone is a hormone produced by the human adrenal glands to regulate the salt and water stability in the body.
In medical conditions such as heart failure and liver cirrhosis, there is an increase in the aldosterone levels in blood. Excess aldosterone hormone in the body induces the kidneys to retain large amounts of salt and fluid while reducing the potassium levels in the body.
Spironolactone tablets control the aldosterone hormone, resulting in the normal function of kidneys i.e. excreting salt and fluid through the urine while retaining potassium. Spironolactone tablets are, hence, known as potassium-sparing diuretic which means that it is a drug which promotes the release of urine (diuretic) while inducing the kidneys to retain potassium.

Storage Instructions for Spironolactone Tablets (Generic Spironolactone)

Store the pack of Generic Spironolactone tablets at room temperature (20°C to 25°C). Keep it protected from heat, moisture, and sunlight. Keep the pack of Spironolactone tablets away from the reach of children and pets.
Do not dispose Spironolactone tablets along with domestic waste or sewage. Consult your doctor or pharmacist about the correct method of disposal.

Contraindications

Aldactone tablets are contraindicated in patients with medical conditions such as anuria, acute renal insufficiency, significant impairment of renal excretory function, and hyperkalemia.

Overdose

An overdose of Generic Spironolactone tablets (Aldactone) may result in symptoms such as irregular heartbeat, nervousness, numbness or tingling in the hands, feet, or lips, rash with flat lesions or small raised lesions on the skin, reddened skin, or weakness or heaviness of the legs.
Inform your doctor immediately if you develop these medical conditions.

Warnings and Precautions to be taken when using Aldactone Tablets (Generic Spironolactone)

Medical History
Before starting your course of Aldactone medication, discuss your personal and family medical history with your doctor. Patients who have the following medical conditions should not use Spironolactone tablets: kidney disease, inability to urinate (anuria); Addison's disease (an adrenal gland disorder); high levels of potassium in your blood (hyperkalemia); untreated mineral imbalance (e.g., low sodium); or if you are also taking eplerenone.
Make sure that your doctor is informed of the following medical conditions before you begin the course of Spironolactone tablets: liver disease; heart disease; an electrolyte imbalance (such as low levels of magnesium in your blood).
Allergies
Before starting Spironolactone tablets, inform your doctor or pharmacist if you are allergic or have had any allergic reactions in the past to Spironolactone or to any of its inactive ingredients.
Drug Interactions
Some medications may interact with Aldactone tablets. Inform your doctor or pharmacist of all your current medications such as prescription medicines, over-the-counter drugs, herbal products, vitamins, mineral supplements, etc. Spironolactone tablets are not commonly used in combination with drugs that can raise blood potassium levels, such as potassium supplements, ACE (angiotensin converting enzyme) inhibitors (Vasotec), NSAIDs (non-steroidal anti-inflammatory drugs like ibuprofen or indomethacin), or other potassium-sparing diuretics.
Spironolactone tablets can cause elevation of blood digoxin (Lanoxin) to toxic levels, requiring alteration of the digoxin dosage.
What to Avoid During Treatment with Spironolactone Tablets
Avoid alcohol consumption during the course of Spironolactone tablets because alcohol can increase certain side effects of Aldactone.
Avoid the consumption of salt substitutes or low-sodium milk products that contain potassium during the course of Spironolactone tablets because such products could increase your potassium levels.
Make sure that you avoid a high-salt diet during your course of Spironolactone tablets. Excess salt will result in water retention, which may lessen the efficacy of Aldactone tablets. Aldactone tablets may weaken your judgment to make good decisions or reflex actions. Be cautious if you drive or perform any activity that requires you to be attentive. Always keep your body hydrated during exercise and in warm weather conditions.
Consult your doctor about the type and amount of liquids you should consume. In some cases, consuming excessive oral fluids can be as harmful as not drinking an adequate amount.
Altering Potassium Levels
Spironolactone tablets can increase the potassium levels in your blood. The chances of this occurrence is higher in patients with kidney problems, diabetes, senior citizens, or if the patient is severely ill. To avoid this condition, the potassium levels of such patients must be closely examined. If not treated on time, high potassium levels can be lethal.
Before the consumption of potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist. Closely monitor your consumption of foods high in potassium such as bananas, tomatoes, potatoes, and low-salt milk. Inform your doctor immediately if you experience muscle weakness, slow or irregular heartbeat.
Gynecomastia
Patients taking Spironolactone tablets may develop gynecomastia during treatment. Such medical complications are thought to develop due to the medication dosage level and treatment period.
Such medical conditions are usually reversible after the treatment period has elapsed. In rare occurrences, breast swelling may endure even after the discontinuation of Spironolactone tablets.
Medical Tests and Surgery During Treatment with Spironolactone Tablets
During the course of Aldactone tablets, you may require regular blood tests to monitor the potassium levels in blood. Spironolactone is known interfere with some medical test results.
Inform any doctor who treats you about your Spironolactone treatment. If you require surgery during your treatment with Spironolactone tablets, inform the surgeon well in advance of your Aldactone medication because you may need to discontinue the treatment temporarily.

Overdosage of Spironolactone Tablets

An overdose of Spironolactone tablets may result in symptoms such as irregular heartbeat, nervousness, numbness or tingling in the hands, feet, or lips, rash with flat lesions or small raised lesions on the skin, reddened skin, or weakness or heaviness of the legs. Inform your doctor immediately if you develop these medical conditions.

Side Effects of Spironolactone Tablets

The following side effects have been reported during the course of Spironolactone tablets (Aldactone):

• Allergic reactions: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
• Digestive: Gastric bleeding, ulceration, gastritis, diarrhea, abdominal cramping, nausea, dry mouth, excessive thirst, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.
• Endocrine: Gynecomastia (enlarged breasts in men or breast tenderness in women), inability to achieve or maintain erection, change in sexual ability, deepening of voice, irregular menses or amenorrhea, postmenopausal bleeding. The possibility of developing breast cancer due to the treatment with Spironolactone tablets has not yet been established.
• Hematologic: Agranulocytosis.
• Hypersensitivity:
• Fever, urticaria, maculopapular or erythematous cutaneous eruptions, anaphylactic reactions, vasculitis, fast/slow heart rate, bleeding gums, unusual tiredness, unusual muscle weakness, skin rash, weak pulse, fainting, shallow breathing (breathing may stop); or feeling like you might pass out.
• Metabolism: Hyperkalemia, rapid weight loss
• Nervous system /psychiatric: Mental confusion, ataxia, headache, drowsiness, lethargy, slurred speech, hallucinations, loss of coordination, feeling unsteady, seizure (convulsions).
• Liver: Mixed cholestatic/hepatocellular toxicity
• Renal: Renal dysfunction (including renal failure), increased urination, little or no urination.
• Skin: Stevens-Johnson Syndrome, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms (DRESS).

The symptoms of gynecomastia, impotence or diminished libido in male patients and cases of hirsutism, oligomenorrhea, amenorrhea, menorrhagia, and breast tenderness in female patients are regarded as long-term effects of Spironolactone treatment.
Inform your doctor immediately if you experience any of these side effects. This is not a comprehensive list of all the possible side effects. If you develop any other medical conditions during the course of Spironolactone tablets, please consult your doctor immediately.

Aldactone Tablets (Generic Spironolactone) during Pregnancy and Breast Feeding

Spironolactone has been classified by the US FDA as Pregnancy Category C.
It is still unknown if Aldactone tablets have a harmful effect on an unborn baby. Inform your doctor if you are pregnant or plan to start a family during the course of Spironolactone tablets. Aldactone tablets should be used only when it is absolutely required during pregnancy. Consult your doctor about the possible risks and benefits of Spironolactone tablets to you and your baby before its consumption.
An active metabolite of Spironolactone called Canrenone, is known to pass through breast milk and may harm a nursing baby. Mothers on a course of Spironolactone tablets should not breast-feed during treatment and should consult their doctor before breast-feeding.

Buy Aldactone 25 mg, 50 mg and 100 mg Tablets Online From Only $0.16 per Pill

You can buy generic Spironolactone tablets online from Everest Online Pharmacy at a cheap price. Aldactone 25 mg, 50 mg and 100 mg pills, manufactured by RPG Life Sciences, India are supplied in a blister strip of 15 tablets. The 25 mg tablets cost only $0.16 per unit when you place an order for 450 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith, it is without a warrant of any kind, expressed or implied.

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